Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Eric H, Bernicker"'
Autor:
Jianming Shao, Yitian Xu, Randall J. Olsen, Saro Kasparian, Kai Sun, Sunil Mathur, Jun Zhang, Chuan He, Shu-Hsia Chen, Eric H. Bernicker, Zejuan Li
Publikováno v:
Cells, Vol 13, Iss 8, p 715 (2024)
Immune checkpoint inhibitors (ICIs) drastically improve therapeutic outcomes for lung cancer, but accurately predicting individual patient responses to ICIs remains a challenge. We performed the genome-wide profiling of 5-hydroxymethylcytosine (5hmC)
Externí odkaz:
https://doaj.org/article/420b9c0e33134000b039a23175fb6661
Autor:
Ethan A. Burns, MD, Wan Hsiang Chen, MD, Sunil Mathur, PhD, Ryan B. Kieser, MD, Jun Zhang, MD, Eric H. Bernicker, MD
Publikováno v:
JTO Clinical and Research Reports, Vol 4, Iss 10, Pp 100570- (2023)
Introduction: The aim of this study is to evaluate treatment patterns, survival outcomes, and factors influencing systemic treatment decisions in adults 80 years and older with NSCLC. Methods: This was a retrospective National Cancer Database study e
Externí odkaz:
https://doaj.org/article/c04c1d846308430fa535fb49bf5ec2a7
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
This article presents a case of a 62-year-old Vietnamese woman with a history of Lynch syndrome (LS), who developed lung adenocarcinoma with EGFR L858R mutation. LS is an autosomal dominant cancer predisposition syndrome caused by a pathogenic germli
Externí odkaz:
https://doaj.org/article/55816eef3d0c4a908904fd96dab55902
Publikováno v:
Cells, Vol 13, Iss 4, p 298 (2024)
Accurate prognostic markers are essential for guiding effective lung cancer treatment strategies. The level of 5-hydroxymethylcytosine (5hmC) in tissue is independently associated with overall survival (OS) in lung cancer patients. We explored the pr
Externí odkaz:
https://doaj.org/article/9aa30aca326b4372ae361f85158e4404
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 4, Pp n/a-n/a (2022)
Abstract Background Early cancer detection can dramatically improve clinical outcomes and greatly reduce economic burden of patients. Plasma cell–free DNA (cfDNA) 5‐hydroxymethylcytosine (5hmC) is an emerging epigenetic marker for cancer diagnosi
Externí odkaz:
https://doaj.org/article/a220871cab1e4e918abf127855f13e64
Autor:
Jim Hsu, Joseph F Annunziata, Ethan Burns, Eric H Bernicker, Randall J Olsen, Jessica S Thomas
Publikováno v:
Clinical Pathology, Vol 15 (2022)
Background: KRAS mutations are the most common oncogenic driver mutations of non-small cell lung cancer (NSCLC) in the Western world. Mutations of the KRAS gene are most prevalent in the patient population of current and former cigarette smokers. Wit
Externí odkaz:
https://doaj.org/article/14b0b8543b0346978604e28f51e8914d
Publikováno v:
JACC. CardioOncology, Vol 1, Iss 2, Pp 172-178 (2019)
Objectives: The goal of this study was to compare the risk of cardiotoxicity with osimertinib versus all other drugs and versus epidermal growth factor receptor (EGFR)–tyrosine kinase inhibitors (TKIs) (erlotinib, afatinib, and gefitinib) in the U.
Externí odkaz:
https://doaj.org/article/50220951c1c64cb08a7fcb5a1138cf47
Autor:
Kalyan R. Chitturi, DO, Jiaqiong Xu, PhD, Raquel Araujo-Gutierrez, MD, Arvind Bhimaraj, MD, Ashrith Guha, MD, Imad Hussain, MD, Mahwash Kassi, MD, Eric H. Bernicker, MD, Barry H. Trachtenberg, MD
Publikováno v:
JACC. CardioOncology, Vol 1, Iss 2, Pp 182-192 (2019)
Objectives: The purpose of this study was to evaluate whether immune checkpoint inhibitors (ICIs) are associated with an increased risk of major adverse cardiovascular events (MACE) compared with non-ICI therapies in patients with lung cancer. Backgr
Externí odkaz:
https://doaj.org/article/a50f3abb8ce94285a27aa93ccd768440
Autor:
Neil Chevli, MD, Stephen B. Chiang, MD, Andrew M. Farach, MD, Waqar Haque, MD, Raj Satkunasivam, MD, Eric H. Bernicker, MD, Ramiro Pino, PhD, E. Brian Butler, MD, Bin S. Teh, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 6, Pp 100719- (2021)
Purpose: Stereotactic body radiation therapy (SBRT) treatment planning for renal cell carcinoma requires accurate delineation of tumor from normal tissue due to the radiosensitivity of normal renal cortical tissue. Tc-99m dimercapto succinic acid (DM
Externí odkaz:
https://doaj.org/article/afc74d8b8bef446a928ee042c511b219
Autor:
Neil Chevli, MD, Andrew Hunt, MD, Waqar Haque, MD, Andrew M. Farach, MD, Jay A. Messer, MD, Suporn Sukpraprut-Braaten, PhD, Eric H. Bernicker, MD, Jun Zhang, MD, E. Brian Butler, MD, Bin S. Teh, MD
Publikováno v:
Advances in Radiation Oncology, Vol 6, Iss 6, Pp 100783- (2021)
Purpose: Patients with small cell lung cancer (SCLC) who have brain metastases require whole-brain radiation therapy (WBRT). When there is no emergent indication for WBRT, patients may receive systemic therapy first and WBRT afterward. In scenarios w
Externí odkaz:
https://doaj.org/article/23b77eca786246599871a488f00203c1