Combining imaging flow cytometry and machine learning for high-throughput schistocyte quantification: A SVM classifier development and external validation cohort

Autor: Julien Demagny, Camille Roussel, Maïlys Le Guyader, Eric Guiheneuf, Véronique Harrivel, Thomas Boyer, Momar Diouf, Michaël Dussiot, Yohann Demont, Loïc Garçon

Publikováno v: EBioMedicine, Vol 83, Iss , Pp 104209- (2022)

Summary: Background: Schistocyte counts are a cornerstone of the diagnosis of thrombotic microangiopathy syndrome (TMA). Their manual quantification is complex and alternative automated methods suffer from pitfalls that limit their use. We report a m

Externí odkaz: https://doaj.org/article/ddc21e42b1544d48b2a77fde1d004541

Supplementary Data from Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma

Autor: Thierry Fest, Vincent Ribrag, Karin Tarte, Fabrice Jardin, Thierry Lamy, Pascal Godmer, Marc-Antoine Belaud-Rotureau, Catherine Henry, Gersende Caron, Valérie Camara-Clayette, Jérôme Le Priol, Eric Guiheneuf, Cédric Pastoret, Francisco Llamas-Gutierrez, Céline Pangault, Mikaël Roussel, Fabienne Desmots

Figure S1 : (A) The 1769-genes signature corresponding to CB/CC transition and CB response to IL-21/CD40L co-stimulation and that are differentially expressed in FL compared to CC and CB were explored using Ingenuity Pathway Analysis (IPA). IPA enric

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a6ac642ed71a057543286c71e80cba0
https://doi.org/10.1158/1078-0432.22474250.v1

Severe airport malaria complicated by macrophage activation syndrome

Autor: Charlotte Tredez, Antoine Gourmel, Justine Crestia, Eric Guiheneuf, Thomas Boyer

Publikováno v: British journal of haematology. 191(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4705a7e2f488eb56817d62c13e90eb1
https://pubmed.ncbi.nlm.nih.gov/33094847

Pan-HDAC Inhibitors Restore PRDM1 Response to IL21 in CREBBP-Mutated Follicular Lymphoma

Autor: Marc-Antoine Belaud-Rotureau, Eric Guiheneuf, Thierry Lamy, Jerome Le Priol, Fabrice Jardin, Céline Pangault, Gersende Caron, Catherine Henry, Mikael Roussel, Valérie Camara-Clayette, Francisco Llamas-Gutierrez, Thierry Fest, Pascal Godmer, Fabienne Desmots, Vincent Ribrag, Karin Tarte, Cedric Pastoret

Publikováno v: Clinical Cancer Research
Clinical Cancer Research, 2019, 25 (2), pp.735-746. ⟨10.1158/1078-0432.CCR-18-1153⟩
Clinical Cancer Research, American Association for Cancer Research, 2019, 25 (2), pp.735-746. ⟨10.1158/1078-0432.CCR-18-1153⟩

Purpose: Follicular lymphoma arises from a germinal center B-cell proliferation supported by a bidirectional crosstalk with tumor microenvironment, in particular with follicular helper T cells (Tfh). We explored the relation that exists between the d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::878815d0888bc42b2920db345ca5901a
https://univ-rennes.hal.science/hal-01952302/document

It is not always malaria: diagnosis of Borrelia recurrent fever on blood smear

Autor: Eric, Guiheneuf, Nicolas, Desjardins, Raphaël, Guiheneuf

Publikováno v: Annales de biologie clinique. 76(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7f43e7ede78ed1f3d83c77f088761879
https://pubmed.ncbi.nlm.nih.gov/29386143