Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eric Greve"'
Autor:
Shilah Bonnett, Jo-Ann Jee, Somsundaram Chettiar, Yulia Ovechkina, Aaron Korkegian, Eric Greve, Joshua Odingo, Tanya Parish
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT We identified an amino-benzothiazole scaffold from a whole-cell screen against recombinant Mycobacterium tuberculosis under expressing the essential signal peptidase LepB. The seed molecule had 2-fold higher activity against the LepB hypomor
Externí odkaz:
https://doaj.org/article/94267a8ccf5149a3a45a4863db471f73
Autor:
Shilah Bonnett, Jo-Ann Jee, Somsundaram Chettiar, Yulia Ovechkina, Aaron Korkegian, Eric Greve, Joshua Odingo, Tanya Parish
We identified an amino-benzothiazole scaffold from a whole cell screen against recombinantMycobacterium tuberculosisunder expressing the essential signal peptidase LepB. The seed molecule had two-fold higher activity against the LepB hypomorph. Throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e2a94611b9adb8f441e7171152d5e077
https://doi.org/10.1101/2022.09.23.509298
https://doi.org/10.1101/2022.09.23.509298
Publikováno v:
Macromolecules. 52:5722-5734
We investigate the impact of center segment dispersity on the phase behavior of 17 lithium salt-doped poly(styrene-block-oligo(ethylene oxide) carbonate-block-styrene) (bSOS) triblock polymers, in ...
Publikováno v:
Synthesis. 51:450-462
Bifunctional catalyst systems for the direct addition of ketones to unactivated alkenes/alkynes were designed and modeled by density functional theory (DFT). The designed catalysts possess bidentate ligands suitable for binding of pi-acidic group 1
Autor:
Robert Flaumenhaft, Christina Scartelli, Chris Dockendorff, Sergey V. Lindeman, Eric Greve, Lin Lin
Publikováno v:
Org Biomol Chem
The enzyme protein disulfide isomerase (PDI) is essential for the correct folding of proteins and the activation of certain cell surface receptors, and is a promising target for the treatment of cancer and thrombotic conditions. A previous high-throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7030d085129ea42a7fed86c8b69337b
https://europepmc.org/articles/PMC7899705/
https://europepmc.org/articles/PMC7899705/
The enzyme protein disulfide isomerase (PDI) is essential for the correct folding of proteins and the activation of certain cell surface receptors, and is a promising target for the treatment of cancer and thrombotic conditions. A previous high-throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55dcb4fc15020cba7fbf12a9225e44a1
https://doi.org/10.26434/chemrxiv.12376469
https://doi.org/10.26434/chemrxiv.12376469
Autor:
Saravanan Subramaniam, Chris Dockendorff, Hartmut Weiler, Allison Stephans, Leggy A. Arnold, N'Guessan D.-R. Diby, Elliot DiMilo, Vladyslava A. Snyder, Ricardo Rosas, Disha M. Gandhi, Teresa H.W. Yeung, Eric Greve, Kaitlin Kentala, Khia E. Kurtenbach
Publikováno v:
Bioorganicmedicinal chemistry. 27(17)
Novel analogs of the allosteric, biased PAR1 ligand ML161 (parmodulin 2, PM2) were prepared in order to identify potential anti-thrombotic and anti-inflammatory compounds of the parmodulin class with improved properties. Investigations of structure-a
Autor:
Disha Gandhi, Ricardo Rosas, Jr., Eric Greve, Kaitlin Kentala, N'Guessan Diby, Vladyslava Snyder, Allison Stephans, Teresa Yeung, Saravanan Subramaniam, Khia Kurtenbach, Elliot DiMilo, Leggy Arnold, Hartmut Weiler, Chris Dockendorff
Novel analogs of the allosteric, biased PAR1 ligand ML161 (parmodulin 2, PM2) were prepared in order to identify potential anti-thrombotic and anti-inflammatory compounds of the parmodulin class with improved properties. Investigations of structure-a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4105f5773805e9ed4e20bd6520779595
https://doi.org/10.26434/chemrxiv.7755479.v1
https://doi.org/10.26434/chemrxiv.7755479.v1
Dual amine/pi Lewis acid catalyst systems have been reported for intramolecular direct additions of aldehydes/ketones to unactivated alkynes and occasionally alkenes, but related intermolecular reactions are rare and not presently of significant synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97745ce99919f41f1fdf1517413a654c
https://doi.org/10.26434/chemrxiv.7538114.v1
https://doi.org/10.26434/chemrxiv.7538114.v1
Bifunctional catalyst systems for the direct addition of ketones to unactivated alkenes/alkynes were designed and modeled by density functional theory (DFT). The designed catalysts possess bidentate ligands suitable for binding of pi-acidic group 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9cdadf40a67e1d522239f937c0fa64b
https://doi.org/10.26434/chemrxiv.6394478.v1
https://doi.org/10.26434/chemrxiv.6394478.v1