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HA antibody mediated FcγRIIIa activity is both dependent on FcR engagement and interactions between HA and sialic acids

Autor: Vincent Klaren, Esther J. M. Stoop, Freek Cox, Eirikur Saeland, Eric Geelen, David Adrianus Theo Zuijdgeest, Bastiaan Smal, Hans J. W. M. Korse, Martin Koldijk, Ted Kwaks, Ronald Vogels, Boerries Brandenburg, Lisanne Tettero, Wouter Koudstaal, Robert Heinz Edward Friesen, Jaap Goudsmit

Publikováno v: Frontiers in Immunology, Vol 7 (2016)
Frontiers in immunology, 7. Frontiers Media S.A.
Frontiers in Immunology

Interactions with receptors for the Fc region of IgG (Fc gamma Rs) have been shown to contribute to the in vivo protection against influenza A viruses provided by broadly neutralizing antibodies (bnAbs) that bind to the viral hemagglutinin (HA) stem.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61e5d44342da377c6a4b9fa5c960fc55
http://journal.frontiersin.org/Journal/10.3389/fimmu.2016.00399/full

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Spectrum of genetic changes in gastro-esophageal cancer cell lines determined by an integrated molecular cytogenetic approach

Autor: Carla Rosenberg, Winand N.M. Dinjens, Eric Geelen, Hans J. Tanke, Peter L. Pearson, Marije IJszenga, Herman van Dekken

Publikováno v: Cancer Genetics and Cytogenetics. 135:35-41

Adenocarcinomas arising around the gastro-esophageal junction (GEJ) are highly malignant, and their incidence has risen rapidly in the last decades. Cell lines are the basic in vitro system for functional and therapeutic studies in GEJ tumors, but on

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d47b1898af9d5ab25f6783ab014b35
https://doi.org/10.1016/s0165-4608(01)00639-2

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Overrepresentation of the short arm of chromosome 12 is related to invasive growth of human testicular seminomas and nonseminomas

Autor: Jw Oosterhuis, Leendert H. J. Looijenga, R. J. H. L. M. Van Gurp, Eric Geelen, Carla Rosenberg

Publikováno v: Oncogene. 19:5858-5862

Overrepresentation of 12p-sequences, mostly due to isochromosome formation, is the only consistent chromosomal alteration found in invasive testicular germ cell tumors of adolescents and young adults (TGCTs), both seminomas and the various histologic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab67da52795677f7c563b9462bb043af
https://doi.org/10.1038/sj.onc.1203950

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Comparative genomic hybridization of microdissected samples from different stages in the development of a seminoma and a non-seminoma

Autor: Leendert H. J. Looijenga, J. Wolter Oosterhuis, Eric Geelen, Jannie van Echten-Arends, M.C. Mostert, Ruud J.H.L.M. van Gurp, Bauke de Jong, Carla Rosenberg

Publikováno v: The Journal of Pathology. 191:187-192

Human testicular germ cell tumours (TGCTs) of adolescents and adults, both seminomas and non-seminomas, originate from intratubular germ cell neoplasia (IGCN). Comparative genomic hybridization (CGH) was applied to microdissected samples from differe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc53bde274671467504fbd8633591aa8
https://doi.org/10.1002/(sici)1096-9896(200006)191:2<187::aid-path584>3.0.co

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Highly Conserved Protective Epitopes on Influenza B Viruses

Publikováno v: Science, 337(6100), 1343-1348. American Association for the Advancement of Science

Influenza Antibodies, Part B With its ability to reassort in animal hosts like pigs and birds, and to cause pandemics, influenza A viruses are often in the spotlight. However, a substantial portion of the annual flu burden is also the result of influ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81ed058a9ac64993a2c3ae641214d4f8
https://europepmc.org/articles/PMC3538841/

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Novel replication-incompetent vector derived from adenovirus type 11 (Ad11) for vaccination and gene therapy: Low seroprevalence and non-cross-reactivity with Ad5

Autor: Paul H.A. Quax, Menzo J. E. Havenga, Esmeralda van der Helm, Ben Berkhout, Jos M. Grimbergen, Jorn Kaspers, Ronald Vogels, Jerome Custers, Angelique A. C. Lemckert, Lennart Holterman, Sandra Verhaagh, Jaap Goudsmit, Margreet Bakker, Martijn Sieuwerts, Gert Gillissen, Eric Geelen, David Zuijdgeest, Remko Van Der Vlugt

Publikováno v: Journal of virology, 78(23), 13207-13215. American Society for Microbiology

A novel plasmid-based adenovirus vector system that enables manufacturing of replication-incompetent (ΔE1) adenovirus type 11 (Ad11)-based vectors is described. Ad11 vectors are produced on PER.C6/55K cells yielding high-titer vector batches after p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d85ee8ac4a66698d59f389097eb281b
https://pure.amc.nl/en/publications/novel-replicationincompetent-vector-derived-from-adenovirus-type-11-ad11-for-vaccination-and-gene-therapy-low-seroprevalence-and-noncrossreactivity-with-ad5(2c3a610f-3333-49ce-a941-43ef4052dff9).html

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