Výsledky vyhledávání - "Eric G. Midboe"

Susceptibility of Manduca sexta to Cry1Ab toxin of Bacillus thuringiensis correlates directly to developmental expression of the cadherin receptor BT-R1

Autor: Lee A. Bulla, Xuebin Zhang, Mohamed A. Ibrahim, Eric G. Midboe, Natalya B. Griko

Publikováno v: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 151:59-63

The cadherin receptor BT-R(1), localized in the midgut epithelium of the tobacco hornworm, Manduca sexta, is coupled to programmed oncotic-like cell death, which is triggered by the univalent binding of the Cry1Ab toxin of Bacillus thuringiensis (Bt)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67f2cbbcd64eef50cad00244961337b
https://doi.org/10.1016/j.cbpb.2008.05.016

Zobrazit plný text záznamu

Global changes in the expression patterns of RNA isolated from the hippocampus and cortex of VX exposed mice

Autor: James E. Sistrunk, Jason L. Blanton, Eric G. Midboe, Jonathan A. D'Ambrozio

Publikováno v: Journal of Biochemical and Molecular Toxicology. 18:115-123

One of the established activities of the nerve agent VX is inhibition of the enzyme acetylcholinesterase (AChE). This inhibition affects the cholinergic nervous system by decreasing the activity of the neurotransmitter-hydrolyzing enzyme cholinestera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbaf7bd92438d97622337ad2d7ba791f
https://doi.org/10.1002/jbt.20015

Zobrazit plný text záznamu

Expression of a midgut-specific cadherin BT-R1 during the development of Manduca sexta larva

Autor: Eric G. Midboe, Lee A. Bulla, Mehmet Candas

Publikováno v: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 135:125-137

The btr-1 gene of Manduca sexta (GenBank AF319973) encodes a cadherin, BT-R(1) (210-kDa), which contains 12 ectodomain modules in association with a number of motifs potentially involved in interactions with cadherin and integrin. The molecule is a t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40345e947a42cfcba0c86dcd9e1a465b
https://doi.org/10.1016/s1096-4959(03)00054-x

Zobrazit plný text záznamu

Cry1A toxins of Bacillus thuringiensis bind specifically to a region adjacent to the membrane-proximal extracellular domain of BT-R1 in Manduca sexta

Autor: Ratna K. Vadlamudi, W. S A Maaty, Mehmet Candas, J. A. Dorsch, Eric G. Midboe, Natalya B. Griko, Lee A. Bulla

Publikováno v: Insect Biochemistry and Molecular Biology. 32:1025-1036

Many subspecies of the soil bacterium Bacillus thuringiensis produce various parasporal crystal proteins, also known as Cry toxins, that exhibit insecticidal activity upon binding to specific receptors in the midgut of susceptible insects. One such r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d4db735764c1e0c79605516d7ebf396d
https://doi.org/10.1016/s0965-1748(02)00040-1

Zobrazit plný text záznamu

Repeated exposure to sublethal doses of the organophosphorus compound VX activates BDNF expression in mouse brain

Autor: George A. Saviolakis, Jose M. Pizarro, Lucille A. Lumley, Jinesh D. Shah, Eric G. Midboe, Wenling E. Chang, Linnzi K.M. Wright, Arun Alagappan, Christopher L. Robison, James L. Meyerhoff, Mariama J. Bah, Douglas M. Cerasoli

Publikováno v: Toxicological sciences : an official journal of the Society of Toxicology. 126(2)

The highly toxic organophosphorus compound VX [O-ethyl S-[2-(diisopropylamino)ethyl]methylphosphonate] is an irreversible inhibitor of the enzyme acetylcholinesterase (AChE). Prolonged inhibition of AChE increases endogenous levels of acetylcholine a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8416967b23236ecd2e8dfee71f11a4e
https://pubmed.ncbi.nlm.nih.gov/22240983

Zobrazit plný text záznamu

Proteolytic cleavage of the developmentally important cadherin BT-R1 in the midgut epithelium of Manduca sexta

Autor: Lee A. Bulla, Mehmet Candas, Eric G. Midboe, Brian R. Francis, Natalya B. Griko

Publikováno v: Biochemistry. 41(46)

BT-R1 (M(r) = 210 kDa) represents a new type of insect cadherin that is expressed specifically in the midgut epithelium during growth and development of Manduca sexta larvae. It also is a target receptor for the Cry1A toxins of the entomopathogenic b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::353bbf4fef611aaf8e1640ca3278f3d1
https://pubmed.ncbi.nlm.nih.gov/12427034

Zobrazit plný text záznamu