Dynamics of the full length and mutated heat shock factor 1 in human cells.

Autor: Gaëtan Herbomel, Meike Kloster-Landsberg, Eric G Folco, Edwige Col, Yves Usson, Claire Vourc'h, Antoine Delon, Catherine Souchier

Publikováno v: PLoS ONE, Vol 8, Iss 7, p e67566 (2013)

Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress. Upon stress, HSF1 binds to and transcribes hsp genes and repeated satellite III (sat III) s

Externí odkaz: https://doaj.org/article/6c9b7037a4504e6d9f1982d4e67039e9

The abnormal, mis-localizated HR bmh protein associates with members of the protein processing machinery in the cytoplasm

Autor: Agnes Belly, Stefan Nonchev, Eric G. Folco, Maud-Virginie Brancaz-Bouvier

We have recently mapped a 296 bp deletion at the mouse hairless locus that causes the mutation hairless rhino bald Mill Hill, (Hrrhbmh), (ID:MGI:3039558; J:89321), removing the stop codon and generating a larger mutant protein HR bmh with an addition

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::178aac6f369151f2533729a4618aab32
https://doi.org/10.1101/245423

The anti-tumor drug E7107 reveals an essential role for SF3b in remodeling U2 snRNP to expose the branch point-binding region

Autor: Eric G. Folco, Robin Reed, Kaitlyn E. Coil

Publikováno v: Genes & Development. 25:440-444

Duplex formation between the branch point-binding region (BBR) of U2 snRNA and the branch point sequence (BPS) in the intron is essential for splicing. Both the BBR and BPS interact with the U2 small nuclear ribonucleoprotein (snRNP)-associated SF3b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da637062dae2f8e4aa48974771e96660
https://doi.org/10.1101/gad.2009411

In Vitro Systems for Coupling RNAP II Transcription to Splicing and Polyadenylation

Autor: Robin Reed, Eric G. Folco

Publikováno v: Methods in Molecular Biology ISBN: 9781627039796

Studies over the past several years have revealed that steps in gene expression are extensively coupled to one another both physically and functionally. Recently, in vitro systems were developed for understanding the mechanisms involved in coupling t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfea24d41a1153adcab289b2d5e51dde
https://doi.org/10.1007/978-1-62703-980-2_13

Dynamics of the full length and mutated heat shock factor 1 in human cells

Autor: Eric G. Folco, Edwige Col, Gaetan Herbomel, Claire Vourc'h, Antoine Delon, Yves Usson, Meike Kloster-Landsberg, Catherine Souchier

Publikováno v: PLoS ONE
PLoS ONE, Public Library of Science, 2013, 8 (7), pp.e67566. ⟨10.1371/journal.pone.0067566⟩
PLoS ONE, 2013, 8 (7), pp.e67566. ⟨10.1371/journal.pone.0067566⟩
PLoS ONE, Vol 8, Iss 7, p e67566 (2013)

International audience; Heat shock factor 1 is the key transcription factor of the heat shock response. Its function is to protect the cell against the deleterious effects of stress. Upon stress, HSF1 binds to and transcribes hsp genes and repeated s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d222d3510e5aa8afd2af7a4364e612
https://www.hal.inserm.fr/inserm-00847765