Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Eric Francotte"'
Publikováno v:
Molecules, Vol 21, Iss 12, p 1740 (2016)
A process to immobilize para-methylbenzoyl cellulose (PMBC) on silica gel has been developed and applied to prepare chiral stationary phases (CSPs) for enantioselective chromatography. The immobilization was achieved by simple irradiation of the poly
Externí odkaz:
https://doaj.org/article/6999cf1fb9c84f17869002b0931f0812
Autor:
Eric Francotte
Publikováno v:
CHIMIA, Vol 63, Iss 12 (2009)
The author describes the emergence and development of enantioselective chromatography as a powerful tool for the separation of stereoisomers, on analytical, preparative, and production scale. He summarizes his early contribution to the advance and pr
Externí odkaz:
https://doaj.org/article/9648cce876c840eaa385e36534dfaa2a
Autor:
Jérôme Lacour, Eric Francotte
Publikováno v:
CHIMIA, Vol 62, Iss 6 (2008)
Externí odkaz:
https://doaj.org/article/b29b7341334e42069fad0a4c2292ae72
Autor:
Eric Francotte, Dan Huynh
Publikováno v:
Chirality. 34:711-731
The immobilization of cellulose 3,5-dimethylphenyl carbamate and amylose 3,5-dimethylphenyl carbamate on silica gel carrier was achieved by using photochemical and thermal processes. Both approaches provide an easy access to materials which were appl
Autor:
Tong Zhang, Eric Francotte
Publikováno v:
Journal of Chromatography A. 1467:214-220
A photochemical method for immobilizing polysaccharide derivatives on silica gel has been developed and applied to 4-methylbenzoyl cellulose (PMBC). The photochemically immobilized materials have been used as chiral stationary phases (CSPs) for the c
Autor:
Jérôme Lacour, Eric Francotte, Yeeun Lim, Rocchina Sabia, Geraldine M. Labrador, Zachary S. Breitbach, Johann Bosson, Claudio Villani, Daniel W. Armstrong
Publikováno v:
Chirality. 28:282-289
Cationic hetero[6]helicenes 1+, 2+ and 3+ have been recently disclosed. Herein we report on their enantiomeric separation using high-performance liquid chromatography. Separation of the antipodes can be achieved in preparative scale on neutral adduct
Autor:
Claus Ehrhardt, Jürgen Maibaum, Edwige Lorthiois, Takatoshi Kosaka, Nils Ostermann, Frederic Cumin, Holger Sellner, Eric Francotte, Trixie Wagner
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 25:1782-1786
Recently, we reported on the discovery of (3S,4S)-disubstituted pyrrolidines (e.g., 2) as inhibitors of the human aspartyl protease renin. In our effort to further expand the scope of this novel class of direct renin inhibitors, a new sub-series was
Autor:
Eric Francotte
Publikováno v:
CHIMIA, Vol 71, Iss 7-8 (2017)
From the beginning of the 1980s, the life science industry increasingly recognized the importance of chirality in biological interaction processes, but the methods for preparing optically pure drugs were still limited. Most of the syntheses of chiral
Autor:
Eric Francotte
Publikováno v:
CHIMIA, Vol 63, Iss 12 (2009)
The author describes the emergence and development of enantioselective chromatography as a powerful tool for the separation of stereoisomers, on analytical, preparative, and production scale. He summarizes his early contribution to the advance and pr
Autor:
Eric Francotte, Jan W. Priess, Claudio Valente, Dominik Rufle, Christophe Bury, Luigi La Vecchia, Heiner Schütz, J. Constanze D. Hartwieg
Publikováno v:
Organic Process Research & Development. 18:1120-1127
3,5-Disubstituted piperidines are versatile building blocks that find broad application in medicinal chemistry programs. Here we describe how all four diastereoisomers of a 5-aryl-substituted nipec...