Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Eric Feldsott"'
Autor:
Daohai Yu, Victor Rizzo, Xiongwen Chen, Jonathan P. Lambert, Markus Wallner, Abdelkarim Sabri, Jaslyn Johnson, Carlos Manuel Romero, Yijun Yang, Claire Poulet, Julia Gorelik, Andrew A. Gibb, Polina Gross, Jose L. Sanchez-Alonso, Joanne F Garbincius, Remus M. Berretta, John W. Elrod, Deborah M Eaton, Erdem Varol, Hajime Kubo, Carla Lucarelli, Jean Ross, Steven R. Houser, Eric Feldsott
Publikováno v:
Circulation Research. 128:92-114
Rationale: Ca 2+ -induced Ca 2+ release (CICR) in normal hearts requires close approximation of L-type calcium channels (LTCCs) within the transverse tubules (T-tubules) and RyR (ryanodine receptors) within the junctional sarcoplasmic reticulum. CICR
Autor:
Timothy A. McKinsey, Sadia Mohsin, Keith A. Koch, Alexander R. Hobby, Alaina L. Headrick, Yijun Yang, Deborah M Eaton, Hajime Kubo, Yinfei Tan, Justin Kurian, Eric Feldsott, Mohsin Khan, Stefania Gallucci, Steven R. Houser, Remus M. Berretta, Marcello Rubino
Publikováno v:
Am J Physiol Heart Circ Physiol
Acute damage to the heart, as in the case of myocardial infarction (MI), triggers a robust inflammatory response to the sterile injury that is part of a complex and highly organized wound-healing process. Cortical bone stem cell (CBSC) therapy after
Autor:
Giulia Borghetti, Eric Feldsott, Thomas E. Sharp rd, Steven R. Houser, Sadia Mohsin, Remus M. Berretta, Alexander R. Hobby
Publikováno v:
Am J Physiol Heart Circ Physiol
Ischemic heart diseases such as myocardial infarction (MI) are the largest contributors to cardiovascular disease worldwide. The resulting cardiac cell death impairs function of the heart and can lead to heart failure and death. Reperfusion of the is
Autor:
Alaina Headrick, Keith A. Koch, Eric Feldsott, Timothy A. McKinsey, Sadia Mohsin, Steve R. Houser, Giana Schena, Yijun Yang, Hajime Kubo
Publikováno v:
Circulation Research. 127
Rationale: Heart failure is the one of the leading causes of death in the United States. Post-myocardial infarction is followed by cardiac remodeling that involves extensive fibrosis and ultimately progresses into heart failure. We have seen improvem
Autor:
Steven R. Houser, Remus M. Berretta, Eric Feldsott, Yijun Yang, Sadia Mohsin, Alexander R Hoachlandr-Hobby, Hajime Kubo
Publikováno v:
Circulation Research. 127
Acute injuries to the heart, like myocardial infarction (MI), contribute to the development and pathology of heart failure (HF). Reperfusion of the ischemic heart greatly increases survival but results in reperfusion injury that can account for up to
Autor:
Markus Wallner, Chen Zhang, Sadia Mohsin, Danielle M. Trappanese, Steven R. Houser, Giulia Borghetti, Remus M. Berretta, Thomas E. Sharp, Xiongwen Chen, Constantine D Troupes, Xiaoxiao Zhang, Yijun Yang, Polina Gross, Eric Feldsott, Neil Zalavadia, Amir Toib, Shavonn C. Harper, Hajime Kubo
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 313:H620-H630
Hypertrophic cardiomyopathy (HCM) is one of the most common genetic cardiac diseases and among the leading causes of sudden cardiac death (SCD) in the young. The cellular mechanisms leading to SCD in HCM are not well known. Prolongation of the action
Autor:
Sadia Mohsin, Giulia Borghetti, Remus M. Berretta, Eric Feldsott, Steven R. Houser, Alexander R. Hobby, Deborah M Eaton, Hajime Kubo
Publikováno v:
Circulation Research. 125
Ischemic heart diseases like myocardial infarction are the largest contributors to cardiovascular disease world-wide. The resulting cardiac cell death impairs function of the heart and can lead to heart failure and death. Re-perfusion of the ischemic
Autor:
Giulia Borghetti, Deborah M Eaton, Sadia Mohsin, Jaslyn Johnson, Steven R. Houser, Hajime Kubo, Eric Feldsott, Giana Schena, Yijun Yang, Remus M. Berretta
Publikováno v:
Circulation Research. 125
Rationale: Post-myocardial infarction (MI) results in remodeling that leads to the development of heart failure. We have previously seen improvements in post-MI wound healing and scar formation as a result of administration of cortical bone stem cell
Autor:
Yijun Yang, Abdel Karim Sabri, Giulia Borghetti, Maria Myzithras, Priyanka Gupta, Hajime Kubo, Eric Feldsott, Jaslyn Johnson, Huaqing Zhao, Markus Wallner, Steven R. Houser, Xinji Gou, Ashraf Khalil, Michael Franti, Yunichel Joo, Tao Wang, Shavonn C. Harper
Publikováno v:
Circulation research. 123(11)
Rationale: Possible beneficial effects of GDF11 (growth differentiation factor 11) on the normal, diseased, and aging heart have been reported, including reversing aging-induced hypertrophy. These effects have not been well validated. High levels of
Autor:
Eric Feldsott, Sadia Mohsin, Steven R. Houser, Hajime Kubo, Alexander R. Hobby, Thomas E. Sharp, Remus M. Berretta
Publikováno v:
Circulation Research. 123
Rationale: Cortical-bone derived stem cells (CBSCs) improve cardiac pump function and reduce scar size after myocardial infarction (MI) compared to Cardiac-Derived and Mesenchymal Stem Cells. However, the mechanism for these improved outcomes is not