Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Eric Farrell"'
Autor:
Claudia Siverino, Shorouk Fahmy-Garcia, Viktoria Niklaus, Nicole Kops, Laura Dolcini, Massimiliano Maraglino Misciagna, Yanto Ridwan, Eric Farrell, Gerjo J.V.M. van Osch, Joachim Nickel
Publikováno v:
Bioactive Materials, Vol 29, Iss , Pp 241-250 (2023)
Bone Morphogenetic proteins (BMPs) like BMP2 and BMP7 have shown great potential in the treatment of severe bone defects. In recent in vitro studies, BMP9 revealed the highest osteogenic potential compared to other BMPs, possibly due to its unique si
Externí odkaz:
https://doaj.org/article/45dfb93b0ed2401c8fd6e92803bdb4e3
Autor:
Jietao Xu, Jana Vecstaudza, Marinus A. Wesdorp, Margot Labberté, Nicole Kops, Manuela Salerno, Joeri Kok, Marina Simon, Marie-Françoise Harmand, Karin Vancíková, Bert van Rietbergen, Massimiliano Maraglino Misciagna, Laura Dolcini, Giuseppe Filardo, Eric Farrell, Gerjo J.V.M. van Osch, Janis Locs, Pieter A.J. Brama
Publikováno v:
Materials Today Bio, Vol 25, Iss , Pp 100959- (2024)
Osteochondral defect repair with a collagen/collagen-magnesium-hydroxyapatite (Col/Col-Mg-HAp) scaffold has demonstrated good clinical results. However, subchondral bone repair remained suboptimal, potentially leading to damage to the regenerated ove
Externí odkaz:
https://doaj.org/article/1b681f9258a043c7b604fc7b7878aa2b
Autor:
Imke Jansen, Hanneke Crielaard, Tamar Wissing, Carlijn Bouten, Frank Gijsen, Ali C. Akyildiz, Eric Farrell, Kim van der Heiden
Publikováno v:
APL Bioengineering, Vol 7, Iss 3, Pp 036120-036120-9 (2023)
Rupture of the cap of an atherosclerotic plaque can lead to thrombotic cardiovascular events. It has been suggested, through computational models, that the presence of microcalcifications in the atherosclerotic cap can increase the risk of cap ruptur
Externí odkaz:
https://doaj.org/article/7face8a92f5d4dfd915e5821c026d6f9
Autor:
Amaia Garmendia Urdalleta, Mathijs Van Poll, Niamh Fahy, Janneke Witte-Bouma, Willem Van Wamel, Iulian Apachitei, Amir A. Zadpoor, Lidy E. Fratila-Apachitei, Eric Farrell
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Macrophage responses following the implantation of orthopaedic implants are essential for successful implant integration in the body, partly through intimate crosstalk with human marrow stromal cells (hMSCs) in the process of new bone formation. Addi
Externí odkaz:
https://doaj.org/article/9ee81ae85f0f42618dbc1ab93e8d4369
Autor:
Encheng Ji, Lieke Leijsten, Janneke Witte-Bouma, Adelin Rouchon, Nunzia Di Maggio, Andrea Banfi, Gerjo J. V. M. van Osch, Eric Farrell, Andrea Lolli
Publikováno v:
Cells, Vol 12, Iss 8, p 1202 (2023)
Tissue engineering bone via endochondral ossification requires the generation of a cartilage template which undergoes vascularisation and remodelling. While this is a promising route for bone repair, achieving effective cartilage vascularisation rema
Externí odkaz:
https://doaj.org/article/e0266716befe460795fd0fe63ce847ef
Autor:
Jietao Xu, Shorouk Fahmy-Garcia, Marinus A. Wesdorp, Nicole Kops, Lucia Forte, Claudio De Luca, Massimiliano Maraglino Misciagna, Laura Dolcini, Giuseppe Filardo, Margot Labberté, Karin Vancíková, Joeri Kok, Bert van Rietbergen, Joachim Nickel, Eric Farrell, Pieter A. J. Brama, Gerjo J. V. M. van Osch
Publikováno v:
Journal of Functional Biomaterials, Vol 14, Iss 2, p 111 (2023)
Despite promising clinical results in osteochondral defect repair, a recently developed bi-layered collagen/collagen-magnesium-hydroxyapatite scaffold has demonstrated less optimal subchondral bone repair. This study aimed to improve the bone repair
Externí odkaz:
https://doaj.org/article/f851bc6d81cd4f228cab2b3a0e38372f
Publikováno v:
Otolaryngology Case Reports, Vol 20, Iss , Pp 100303- (2021)
Eagles syndrome, which is due to calcified stylohyoid ligaments or an elongated styloid process, may manifest as chronic throat pain. It is not usually implicated in trauma. This case report is unique in that we describe firstly a complete bony ring
Externí odkaz:
https://doaj.org/article/b3c0be5791ae41e19c0547131535ad18
Autor:
Niamh Fahy, Virginia Palomares Cabeza, Andrea Lolli, Janneke Witte-Bouma, Ana Merino, Yanto Ridwan, Eppo B. Wolvius, Martin J. Hoogduijn, Eric Farrell, Pieter A. J. Brama
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Tissue engineering approaches using progenitor cells such as mesenchymal stromal cells (MSCs) represent a promising strategy to regenerate bone. Previous work has demonstrated the potential of chondrogenically primed human MSCs to recapitulate the pr
Externí odkaz:
https://doaj.org/article/2ccee5bd73af415794d040e212bdfe7f
Autor:
Claudia Siverino, Shorouk Fahmy-Garcia, Didem Mumcuoglu, Heike Oberwinkler, Markus Muehlemann, Thomas Mueller, Eric Farrell, Gerjo J. V. M. van Osch, Joachim Nickel
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3928 (2022)
For the treatment of large bone defects, the commonly used technique of autologous bone grafting presents several drawbacks and limitations. With the discovery of the bone-inducing capabilities of bone morphogenetic protein 2 (BMP2), several delivery
Externí odkaz:
https://doaj.org/article/45905e380ec4481ea3bfc32d2fb16479
Autor:
Yannick Nossin, Eric Farrell, Wendy J. L. M. Koevoet, Rodrigo A. Somoza, Arnold I. Caplan, Bent Brachvogel, Gerjo J. V. M. van Osch
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
With rising demand for cartilage tissue repair and replacement, the differentiation of mesenchymal stem cells (BMSCs) into cartilage tissue forming cells provides a promising solution. Often, the BMSC-derived cartilage does not remain stable and cont
Externí odkaz:
https://doaj.org/article/335b3561a931441ab9779d1d2e0416c6