Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Eric F. Adams"'
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 115:683-689
There is growing evidence that cholecystokinin (CCK) affects growth and differentiation of anterior pituitary cells, via the CCK-B receptor. The possibility of an autocrine / paracrine role for CCK to modulate hormone secretion in human pituitary tum
Publikováno v:
Biomaterials. 27:1019-1026
Poly(epsilon-caprolactone) (PCL) fibres were produced by wet spinning from solutions in acetone under low shear (gravity flow) conditions. As-spun PCL fibres exhibited a mean strength and stiffness of 7.9 MPa and 0.1 GPa, respectively and a rough, po
Autor:
R. Fahlbusch, W. Schott, P. Nomikos, Eric F. Adams, A. L. De Oliveira Machado, Michael Buchfelder
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 113:344-349
In this study, the central technique of in vitro culture has been used to further investigate whether LH/FSH-expressing, but clinically "functionless" pituitary adenomas are gonadotropinomas or whether their hormone secretion is due to transdifferent
Publikováno v:
Journal of Medical Sciences, Vol 34, Iss 2, Pp 52-55 (2014)
The classical concept of estrogen receptor (ER) activation is that steroid passes the cell membrane, binds to its specific protein receptor in the cell's cytoplasm and the steroid-receptor complex travels to the nucleus where it activates responsive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64d7f0090afacf2078a5e4f856300bb
https://publications.aston.ac.uk/id/eprint/25568/1/Receptor_for_activated_C_Kinase_1_protein_binds_to_and_activates_the_human_estrogen_receptor_alpha.pdf
https://publications.aston.ac.uk/id/eprint/25568/1/Receptor_for_activated_C_Kinase_1_protein_binds_to_and_activates_the_human_estrogen_receptor_alpha.pdf
Autor:
L. De Marco, Eitan Friedman, H. Bei, F.L. Valle, K. Brandão, Evanguedes Kalapothakis, J.C. Sarubi, Débora Marques de Miranda, Marta Sarquis, Eric F. Adams, W. L. Boson
Publikováno v:
Neuroscience Letters. 310:5-8
Craniopharyngioma is the most common childhood tumor and thought to arise from embryonic remnants of Rathke's pouch. The paucity of published data on the molecular basis of these tumors prompted us to examine 22 adamantinomatous craniopharyngiomas lo
Autor:
Kenji Kangawa, Stephen A. Bustin, Suzanne Jordan, Eric F. Adams, Ashley B. Grossman, Masayasu Kojima, David G. Lowe, Márta Korbonits
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 86:881-887
Ghrelin is a recently identified endogenous ligand of the GH secretagogue (GHS) receptor. It was originally isolated from the stomach, but has also been shown to be present in the rat hypothalamus. It is a 28-amino acid peptide with an unusual octano
Publikováno v:
Biochemical and Biophysical Research Communications. 275:33-36
A previous study has suggested that a G to A base change at position 169 of the GHRH-receptor gene in human somatotrophinomas is a mutation and confers hypersensitivity to GHRH. The alternative base converts codon 57 from GCG to AGC, resulting in rep
Publikováno v:
Pituitary. 1:181-185
We herein review published findings on the clinical characteristics of acromegalic patients harboring pituitary somatotrophinomas expressing adenylyl cyclase activating gsp mutations and present an update of our own data on a large series of 176 pati
Autor:
Eric F. Adams, Boleslaw Goldman, Eitan Friedman, Gad Barkai, Michal Daniely, Rodulf Fahlbusch, Ayala Aviram, Michael Buchfelder
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 83:1801-1805
Clinically nonfunctioning pituitary adenomas constitute about one third of pituitary neoplasms and are considered monoclonal tumors. The molecular mechanisms of tumorigenesis in these neoplasms are poorly understood, as evidenced by the paucity of re
Autor:
Christiane Hamacher, Michael Buchfelder, Rudolf Fahlbusch, Eric F. Adams, Ting Lei, Martina Bröcker, Michael Derwahl
Publikováno v:
Pituitary. 1:13-23
The heterotrimeric Gs protein-adenylyl cyclase (AC) cascade plays a pivotal role in controlling hormone secretion by endocrine glands. Consequently, deficiency of the alpha-subunit of Gs leads to endocrine hypofunction and hypoplasia in the affected