Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eric Erbs"'
Autor:
Adrien Pasquier, Kevin Vivot, Eric Erbs, Coralie Spiegelhalter, Zhirong Zhang, Victor Aubert, Zengzhen Liu, Meryem Senkara, Elisa Maillard, Michel Pinget, Julie Kerr-Conte, François Pattou, Gilbert Marciniak, Axel Ganzhorn, Paolo Ronchi, Nicole L. Schieber, Yannick Schwab, Paul Saftig, Alexander Goginashvili, Romeo Ricci
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Impaired beta-cell insulin secretion is a key pathological feature of type 2 diabetes. Here, the authors describe metabolic stress induced lysosomal degradation of newly formed insulin granules, independent of macroautophagy, as a potential mechanism
Externí odkaz:
https://doaj.org/article/8e0d2438f64c4863b27b51b83a65cf65
Autor:
Meryem Senkara, Michel Pinget, Yannick Schwab, Paul Saftig, Paolo Ronchi, Axel Ganzhorn, Julie Kerr-Conte, Elisa Maillard, Nicole L. Schieber, François Pattou, Zengzhen Liu, Victor Aubert, Alexander Goginashvili, Romeo Ricci, Kevin Vivot, Adrien Pasquier, Coralie Spiegelhalter, Gilbert Marciniak, Eric Erbs, Zhirong Zhang
Publikováno v:
Nature Communications
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-11170-4⟩
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications, 2019, 10 (1), ⟨10.1038/s41467-019-11170-4⟩
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Compromised function of insulin-secreting pancreatic β cells is central to the development and progression of Type 2 Diabetes (T2D). However, the mechanisms underlying β cell failure remain incompletely understood. Here, we report that metabolic st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e6d7dd4c2ebd89d2394b0088c7a9973
https://doi.org/10.1038/s41467-019-11170-4
https://doi.org/10.1038/s41467-019-11170-4
Autor:
Helena de Fatima Magliarelli, Ruedi Aebersold, Mariette Matondo, Izabela Sumara, Michael Mihlan, Romeo Ricci, Zhirong Zhang, Alexander Goginashvili, Gergő Mészáros, Christian Wolfrum, Eric Erbs
Publikováno v:
Cell Death and Disease
Cell Death and Disease, Nature Publishing Group, 2016, 7 (10), pp.e2411-e2411. ⟨10.1038/cddis.2016.312⟩
Cell Death & Disease
Cell Death and Disease, Nature Publishing Group, 2016, 7 (10), pp.e2411-e2411. ⟨10.1038/cddis.2016.312⟩
Cell Death & Disease
Adaptation to changes in nutrient availability is crucial for cells and organisms. Posttranslational modifications of signaling proteins are very dynamic and are therefore key to promptly respond to nutrient deprivation or overload. Herein we screene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48926f1a0cd14bcf60d4a70bcc27ca8c
https://hal.archives-ouvertes.fr/hal-02371041
https://hal.archives-ouvertes.fr/hal-02371041
Autor:
Brigitte L. Kieffer, Dominique Massotte, Audrey Matifas, Eric Erbs, Rhian Alice Ceredig, Lauren Faget, Jean-Luc Vonesch
Publikováno v:
Neuroscience
Neuroscience, 2016, 313, pp.46-56. ⟨10.1016/j.neuroscience.2015.10.022⟩
Neuroscience, 2016, 313, pp.46-56. ⟨10.1016/j.neuroscience.2015.10.022⟩
Delta opioid receptors participate to the control of chronic pain and emotional responses. Recent data also identified their implication in spatial memory and drug-context associations pointing to a critical role of hippocampal delta receptors. To be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d1aa1528870e17f618010bb23aff222
https://doi.org/10.1016/j.neuroscience.2015.10.022
https://doi.org/10.1016/j.neuroscience.2015.10.022
Autor:
Eric Erbs, Brigitte L. Kieffer, Wendy Walwyn, Audrey Matifas, Christopher J. Evans, Amynah A. Pradhan, Chihiro Nozaki, Dominique Filliol
Publikováno v:
The Journal of Neuroscience. 30:16459-16468
δ-Opioid receptors are G-protein-coupled receptors that regulate nociceptive and emotional responses. It has been well established that distinct agonists acting at the same G-protein-coupled receptor can engage different signaling or regulatory resp
Autor:
Pascal Kessler, Carmine Settembre, Izabela Sumara, Michael Mihlan, Eric Erbs, Laura Cinque, Alexander Goginashvili, Yannick Schwab, Joëlle Morvan, Romeo Ricci, Coralie Spiegelhalter, Adrien Pasquier, Zhirong Zhang, Nicole L. Schieber, Ksenia Krupina
Publikováno v:
Science
Science, American Association for the Advancement of Science, 2015, 347 (6224), pp.878-882. ⟨10.1126/science.aaa2628⟩
Science, American Association for the Advancement of Science, 2015, 347 (6224), pp.878-882. ⟨10.1126/science.aaa2628⟩
Pancreatic β cells lower insulin release in response to nutrient depletion. The question of whether starved β cells induce macroautophagy, a predominant mechanism maintaining energy homeostasis, remains poorly explored. We found that, in contrast t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36c6ebff630836e78785c98e0c372280
https://hal.archives-ouvertes.fr/hal-03080550
https://hal.archives-ouvertes.fr/hal-03080550
Autor:
Alessandro Usiello, Emiliana Borrelli, Paolo Calabresi, Eric Erbs, Cinzia Costa, Barbara Picconi, Diego Centonze, Giorgio Bernardi
Publikováno v:
The Journal of Neuroscience. 24:8214-8222
Reduced glutamate-mediated synaptic transmission has been implicated in the pathophysiology of schizophrenia. Because antipsychotic agents might exert their beneficial effects against schizophrenic symptoms by strengthening excitatory transmission in
Autor:
Paolo Gubellini, Eric Erbs, Anne Tscherter, Giorgio Bernardi, Paolo Calabresi, Silvia Rossi, Enrico Bracci, Diego Centonze, Antonio Pisani, Alessandro Usiello, N. Tognazzi, Emiliana Borrelli
Publikováno v:
Neuroscience
Neuroscience, 2004, 129 (1), pp.157-166. ⟨10.1016/j.neuroscience.2004.07.043⟩
Neuroscience, 2004, 129 (1), pp.157-166. ⟨10.1016/j.neuroscience.2004.07.043⟩
Compelling evidence indicates that the long (D2L) and the short (D2S) isoform of dopamine (DA) D2 receptors serve distinct physiological functions in vivo. To address the involvement of these isoforms in the control of synaptic transmission in the st
Publikováno v:
Proceedings of the National Academy of Sciences. 101:325-330
The role played by oligodendrocytes (OLs), the myelinating cells of the CNS, during brain development has not been fully explored. We have addressed this question by inducing a temporal and reversible ablation of OLs on postnatal CNS development. OL
Autor:
Ana B. Martín, Alessandro Usiello, Rosario Moratalla, Emiliana Borrelli, Nadia Tognazzi, Cristina Grande, P. Calabresi, Giorgio Bernardi, Antonio Pisani, Paolo Gubellini, Eric Erbs, Diego Centonze
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
Scopus-Elsevier
instname
Scopus-Elsevier
By stimulating distinct receptor subtypes, dopamine (DA) exerts presynaptic and postsynaptic actions on both large aspiny (LA) cholinergic and fast-spiking (FS) parvalbumin-positive interneurons of the striatum. Lack of receptor- and isoform-specific