Zobrazeno 1 - 10
of 166
pro vyhledávání: '"Eric E. Simanek"'
Autor:
Alexander J. Menke, Nicholas C. Henderson, Lola C. Kouretas, Anne N. Estenson, Benjamin G. Janesko, Eric E. Simanek
Publikováno v:
Molecules, Vol 28, Iss 3, p 1144 (2023)
In the absence of preorganization, macrocyclization reactions are often plagued by oligomeric and polymeric side products. Here, a network of hydrogen bonds was identified as the basis for quantitative yields of macrocycles derived from the dimerizat
Externí odkaz:
https://doaj.org/article/44c2be0cd5704c318b2ffa2c6c97dacc
Publikováno v:
Molecules, Vol 28, Iss 1, p 131 (2022)
Dendrimers are attractive macromolecules for a broad range of applications owing to their well-defined shapes and dimensions, highly branched and globular architectures, and opportunities for exploiting multivalency. Triazine dendrimers in particular
Externí odkaz:
https://doaj.org/article/2cf89b1be676476a91fc907266f51ee4
Autor:
Eric E. Simanek
Publikováno v:
Molecules, Vol 26, Iss 16, p 4774 (2021)
For two decades, methods for the synthesis and characterization of dendrimers based on [1,3,5]-triazine have been advanced by the group. Motivated by the desire to generate structural complexity on the periphery, initial efforts focused on convergent
Externí odkaz:
https://doaj.org/article/fbf9143ef4bb4c3ea0796b5b72278155
Publikováno v:
Biomolecules, Vol 9, Iss 9, p 421 (2019)
Various glutamate urea ligands have displayed high affinities to prostate specific membrane antigen (PSMA), which is highly overexpressed in prostate and other cancer sites. The multivalent versions of small PSMA-targeted molecules are known to be ev
Externí odkaz:
https://doaj.org/article/f76f131d5a8f48b29249c4826fd6f202
Autor:
Fermín Ramírez-Crescencio, Alan E. Enciso, Mirza Hasan, Viviana C. P. da Costa, Onofrio Annunziata, Rocío Redón, Jeffery L. Coffer, Eric E. Simanek
Publikováno v:
Molecules, Vol 21, Iss 5, p 599 (2016)
The synthesis and solubility behaviors of four generation five (G5) triazine dendrimers are studied. While the underivatized cationic dendrimer is soluble in water, the acetylated and propanoylated derivatives undergo coacervation in water upon incre
Externí odkaz:
https://doaj.org/article/d29a3eeae7f54b6abefe9207f930c2e4
Publikováno v:
Molecules, Vol 21, Iss 3, p 335 (2016)
A readily and rapidly accessible triazine dendrimer was manipulated in four steps with 23% overall yield to give a construct displaying four maleimide groups and DOTA. The maleimide groups of the dendrimer are sensitive to hydrolysis under basic cond
Externí odkaz:
https://doaj.org/article/cdd10258273741bda8484eab12bc5209
Nanoparticle Effects on Human Platelets in Vitro: A Comparison between PAMAM and Triazine Dendrimers
Autor:
Alan E. Enciso, Barry Neun, Jamie Rodriguez, Amalendu P. Ranjan, Marina A. Dobrovolskaia, Eric E. Simanek
Publikováno v:
Molecules, Vol 21, Iss 4, p 428 (2016)
Triazine and PAMAM dendrimers of similar size and number of cationic surface groups were compared for their ability to promote platelet aggregation. Triazine dendrimers (G3, G5 and G7) varied in molecular weight from 8 kDa–130 kDa and in surface gr
Externí odkaz:
https://doaj.org/article/d11bb42fa7ae47cfb5e8e846ec693cee
Autor:
Riccardo Capelli, Alexander J. Menke, Hongjun Pan, Benjamin G. Janesko, Eric E. Simanek, Giovanni M. Pavan
Publikováno v:
ACS Omega
Inspired by therapeutic potential, the molecular engineering of macrocycles is garnering increased interest. Exercising control with design, however, is challenging due to the dynamic behavior that these molecules must demonstrate in order to be bioa
Autor:
Alexander J Menke, Joseph M Mellberg, Hongjun Pan, Joseph H Reibenspies, Benjamin G Janesko, Eric E Simanek
Publikováno v:
Chemistry – A European Journal.
Autor:
Alexander J. Menke, Camryn J. Gloor, Liam E. Claton, Magy A. Mekhail, Hongjun Pan, Mikaela D. Stewart, Kayla N. Green, Joseph H. Reibenspies, Giovanni M. Pavan, Riccardo Capelli, Eric E. Simanek
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa283af4215616ad0e6e4a09420461eb
https://hdl.handle.net/11583/2977420
https://hdl.handle.net/11583/2977420