Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Eric E. Beier"'
Autor:
Matthew L. Neal, Eric E. Beier, Muhammad M. Hossain, Alexa Boyle, Jiaying Zheng, Chunki Kim, Isha Mhatre-Winters, Long-Jun Wu, Jason R. Richardson
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 582 (2023)
Although the precise mechanisms for neurodegeneration in Parkinson’s disease (PD) are unknown, evidence suggests that neuroinflammation is a critical factor in the pathogenic process. Here, we sought to determine whether the voltage-gated proton ch
Externí odkaz:
https://doaj.org/article/6fe1e1e16ed141f69c86a1ba7546370c
Publikováno v:
Neurobiology of Disease, Vol 108, Iss , Pp 115-127 (2017)
Inflammation arising from central and/or peripheral sources contributes to the pathogenesis of multiple neurodegenerative diseases including Parkinson's disease (PD). Emerging data suggest that differential activation of glia could lead to the pathog
Externí odkaz:
https://doaj.org/article/8aac6d3a198640fba3a3e8018915d881
Autor:
Elisa Roztocil, Min Yee, J. Edward Puzas, Sydney A. Lim, Collynn F. Woeller, Eric E. Beier, Michael A. O'Reilly
Publikováno v:
Free Radic Biol Med
Preterm birth is a risk factor for growth failure and development of respiratory disease in children and young adults. Their early exposure to oxygen may contribute to lung disease because adult mice exposed to hyperoxia as neonates display reduced l
Autor:
Gelareh Alam, Long Jun Wu, Sheila M. Fleming, Matthew Neal, Kevin M. Budge, Alexa M. Boyle, Eric E. Beier, Chunki Kim, Jason R. Richardson
Publikováno v:
FASEB J
Increased pro-inflammatory cytokine levels and proliferation of activated microglia have been found in Parkinson’s disease (PD) patients and animal models of PD, suggesting that targeting of the microglial inflammatory response may result in neuro-
Publikováno v:
Neurobiology of Disease, Vol 108, Iss, Pp 115-127 (2017)
Inflammation arising from central and/or peripheral sources contributes to the pathogenesis of multiple neurodegenerative diseases including Parkinson's disease (PD). Emerging data suggest that differential activation of glia could lead to the pathog
Publikováno v:
Toxicological Sciences. 149:277-288
The heavy metal lead (Pb) has a deleterious effect on skeletal health. Because bone mass is maintained through a balance of bone formation and resorption, it is important to understand the effect of Pb levels on osteoblastic and osteoclastic activity
Publikováno v:
Environmental Health Perspectives
Background Lead (Pb) exposure and obesity are co-occurring risk factors for decreased bone mass in the young, particularly in low socioeconomic communities. Objectives The goal of this study was to determine whether the comorbidities of Pb exposure a
Autor:
Deborah Dang, Tzong-Jen Sheu, Jonathan D. Holz, Resika Ubayawardena, J. Edward Puzas, Eric E. Beier, Philip Babij
Publikováno v:
Journal of Biological Chemistry. 290:18216-18226
Exposure to lead (Pb) from environmental sources remains an overlooked and serious public health risk. Starting in childhood, Pb in the skeleton can disrupt epiphyseal plate function, constrain the growth of long bones, and prevent attainment of a hi
Autor:
J. Edward Puzas, Regis J. O'Keefe, Kiminori Yukata, Michael J. Zuscik, Tzong-Jen Sheu, Eric E. Beier, Taylor Buckley
Publikováno v:
Journal of Orthopaedic Research. 32:1397-1405
There is strong evidence in the clinical literature to suggest that elevated lead (Pb) exposure impairs fracture healing. Since Pb has been demonstrated to inhibit bone formation, and Wnt signaling is an important anabolic pathway in chondrocyte matu
Autor:
Tzong-Jen Sheu, Michael J. Zuscik, Jason R. Maher, Eric E. Beier, J. Edward Puzas, Andrew J. Berger, Deborah A. Cory-Slechta
Publikováno v:
Environmental Health Perspectives
Background: Exposure to lead (Pb) from environmental and industrial sources remains an overlooked serious public health risk. Elucidating the effect of Pb on bone cell function is therefore critical for understanding its risk associated with diseases