Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Eric E, Bardes"'
Autor:
Kang Jin, Eric E. Bardes, Alexis Mitelpunkt, Jake Y. Wang, Surbhi Bhatnagar, Soma Sengupta, Daniel Pomeranz Krummel, Marc E. Rothenberg, Bruce J. Aronow
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103115- (2021)
Summary: Numerous studies have provided single-cell transcriptome profiles of host responses to SARS-CoV-2 infection. Critically lacking however is a data mine that allows users to compare and explore cell profiles to gain insights and develop new hy
Externí odkaz:
https://doaj.org/article/02a5c99eec9b4449b05e89883b6bdcbf
Autor:
Nathan, Gaddis, Joshua, Fortriede, Minzhe, Guo, Eric E, Bardes, Michal, Kouril, Scott, Tabar, Kevin, Burns, Maryanne E, Ardini-Poleske, Stephanie, Loos, Daniel, Schnell, Kang, Jin, Balaji, Iyer, Yina, Du, Bing-Xing, Huo, Anukana, Bhattacharjee, Jeff, Korte, Ruchi, Munshi, Victoria, Smith, Andrew, Herbst, Joseph A, Kitzmiller, Geremy C, Clair, James P, Carson, Joshua, Adkins, Edward E, Morrisey, Gloria S, Pryhuber, Ravi, Misra, Jeffrey A, Whitsett, Xin, Sun, Trevor, Heathorn, Benedict, Paten, V B Surya, Prasath, Yan, Xu, Tim, Tickle, Bruce J, Aronow, Nathan, Salomonis
Publikováno v:
American journal of respiratory cell and molecular biology.
An improved understanding of the human lung necessitates advanced systems models informed by an ever-increasing repertoire of molecular omics, cellular, imaging, and pathological datasets. To centralize and standardize information across broad lung r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebfd92f60f42256e949d4045e5693141
https://pubmed.ncbi.nlm.nih.gov/36413377
https://pubmed.ncbi.nlm.nih.gov/36413377
Autor:
Xin Sun, Anne-Karina Perl, Rongbo Li, Sheila M. Bell, Eniko Sajti, Vladimir V. Kalinichenko, Tanya V. Kalin, Ravi S. Misra, Hitesh Deshmukh, Geremy Clair, Jennifer Kyle, Laura E. Crotty Alexander, Jorge A. Masso-Silva, Joseph A. Kitzmiller, Kathryn A. Wikenheiser-Brokamp, Gail Deutsch, Minzhe Guo, Yina Du, Michael P. Morley, Michael J. Valdez, Haoze V. Yu, Kang Jin, Eric E. Bardes, Jarod A. Zepp, Terren Neithamer, Maria C. Basil, William J. Zacharias, Jamie Verheyden, Randee Young, Gautam Bandyopadhyay, Sara Lin, Charles Ansong, Joshua Adkins, Nathan Salomonis, Bruce J. Aronow, Yan Xu, Gloria Pryhuber, Jeff Whitsett, Edward E. Morrisey
Publikováno v:
Dev Cell
The human lung plays vital roles in respiration, host defense and basic physiology. Recent technological advancements such as single-cell RNA sequencing and genetic lineage tracing have revealed novel cell types and enriched functional properties of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1347ca12c8d5dc4572a02649cf15fad
https://europepmc.org/articles/PMC9202574/
https://europepmc.org/articles/PMC9202574/
Autor:
Eric E. Bardes, Soma Sengupta, Daniel Pomeranz Krummel, Bruce J. Aronow, Surbhi Bhatnagar, Kang Jin, Jake Y. Wang, Alexis Mitelpunkt, Marc E. Rothenberg
Publikováno v:
iScience, Vol 24, Iss 10, Pp 103115-(2021)
bioRxiv
article-version (status) pre
article-version (number) 2
iScience
bioRxiv
article-version (status) pre
article-version (number) 2
iScience
Numerous studies have provided single-cell transcriptome profiles of host responses to SARS-CoV-2 infection. Critically lacking however is a datamine that allows users to compare and explore cell profiles to gain insights and develop new hypotheses.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bc940a43d86645eb82725bce1451ee6
http://www.sciencedirect.com/science/article/pii/S258900422101083X
http://www.sciencedirect.com/science/article/pii/S258900422101083X
Autor:
Philip Dexheimer, Jeffrey L. Dage, Xianglong Zhang, Thomas J. Ward, Yu-Wen Alvin Huang, Yingfei Liu, Marius Wernig, Zhiping P. Pang, Tamas Danko, ChangHui Pak, Jinzhao Wang, Vincent R. Mirabella, Kang Jin, Michael McLachlan, Madhuri Vangipuram, Carolin Purmann, Jennifer C. Moore, Junyi Ma, Bradley J. Swanson, Sarah Grieder, Eric E. Bardes, Douglas F. Levinson, Alexis Mitelpunkt, Bruce J. Aronow, Alexander E. Urban, Thomas C. Südhof, Pingping Qu
Publikováno v:
Proc Natl Acad Sci U S A
Heterozygous NRXN1 deletions constitute the most prevalent currently known single-gene mutation predisposing to schizophrenia. Previous studies showed that engineered heterozygous NRXN1 deletions impaired neurotransmitter release in human neurons, su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4862173dfbc4ea72fe8169d61db3d2ea
https://doi.org/10.1073/pnas.2025598118
https://doi.org/10.1073/pnas.2025598118
Autor:
Daniel Pomeranz Krummel, Kang Jin, Eric E. Bardes, Jake Y. Wang, Surbhi Bhatnagar, Soma Sengupta, Alexis Mitelpunkt, Marc E. Rothenberg, Bruce J. Aronow
Publikováno v:
SSRN Electronic Journal.
Numerous studies have provided single-cell transcriptome profiles of host responses to SARS-CoV-2 infection. Critically lacking however is a reusable datamine to allow users to compare and explore these data for insight, inference, and hypothesis gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb405beb6d326c5a9e1bddeb01669f72
https://doi.org/10.2139/ssrn.3882891
https://doi.org/10.2139/ssrn.3882891
Autor:
Manesh Shah, David Kainer, B Kirtley Amos, Piet Jones, Bruce J. Aronow, Omar Demerdash, Armin Geiger, Alexis Mitelpunkt, Kang Jin, John Pestian, Daniel Jacobson, Eric E. Bardes, Christiane Alvarez, Erica T. Prates, Michael R. Garvin, Mirko Pavicic
Using a Systems Biology approach, we integrated genomic, transcriptomic, proteomic, and molecular structure information to provide a holistic understanding of the COVID-19 pandemic. The expression data analysis of the Renin Angiotensin System indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3e1e5f420242bf30af615e37a37e1e2
https://doi.org/10.1101/2020.04.06.028712
https://doi.org/10.1101/2020.04.06.028712
Publikováno v:
Nucleic Acids Research
Identifying functionally significant microRNAs (miRs) and their correspondingly most important messenger RNA targets (mRNAs) in specific biological contexts is a critical task to improve our understanding of molecular mechanisms underlying organismal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d018b6cf156ef84a0a706876be39c3e
https://doi.org/10.1093/nar/gku409
https://doi.org/10.1093/nar/gku409
Publikováno v:
Nucleic Acids Research
ToppGene Suite (http://toppgene.cchmc.org; this web site is free and open to all users and does not require a login to access) is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d929577aee6b3421000c3e1a654c627
https://doi.org/10.1093/nar/gkp427
https://doi.org/10.1093/nar/gkp427
Publikováno v:
Pathobiology of Human Disease ISBN: 9780123864574
The ongoing expansion of our knowledge about the molecular basis of structure and function of diverse biological entities and processes presents us with both huge opportunities and challenges to improve our understanding of disease. To accomplish thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::257870e993d98cbc5f185f9b898c58f7
https://doi.org/10.1016/b978-0-12-386456-7.07801-1
https://doi.org/10.1016/b978-0-12-386456-7.07801-1