Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Eric Dominguez"'
Autor:
Adrian D. Hobson, Russell A. Judge, Ana L. Aguirre, Brian S. Brown, Yifang Cui, Ping Ding, Eric Dominguez, Enrico DiGiammarino, David A. Egan, Gail M. Freiberg, Sujatha M. Gopalakrishnan, Christopher M. Harris, Marie P. Honore, Karen L. Kage, Nicolas J. Kapecki, Christopher Ling, Junli Ma, Helmut Mack, Mulugeta Mamo, Stefan Maurus, Bradford McRae, Nigel S. Moore, Bernhard K. Mueller, Reinhold Mueller, Marian T. Namovic, Kaushal Patel, Steve D. Pratt, C. Brent Putman, Kara L. Queeney, Kathy K. Sarris, Lisa M. Schaffter, Vincent Stoll, Anil Vasudevan, Lei Wang, Lu Wang, William Wirthl, Kimberly Yach
Publikováno v:
Journal of Medicinal Chemistry. 61:11074-11100
A HTS campaign identified compound 1, an excellent hit-like molecule to initiate medicinal chemistry efforts to optimize a dual ROCK1 and ROCK2 inhibitor. Substitution (2-Cl, 2-NH
Autor:
Kara L. Queeney, Maria A. Argiriadi, Anil Vasudevan, Jürgen Dinges, Eric Dominguez, Kelly E. Desino, Christopher M. Harris, Grier A. Wallace, Tegest Kebede, Hetal Patel, Denise C. Perron
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:2297-2302
Inhibition of sphingosine-1-phosphate lyase has recently been proposed as a potential treatment option for inflammatory disorders such as multiple sclerosis, rheumatoid arthritis, and inflammatory bowel disease. In this report we describe our hit-to-
Autor:
Grier A. Wallace, Elzbieta Radziejewska, Susan C. Marchie, Jürgen Dinges, Kara L. Queeney, Charles W. Hutchins, David Banach, Christopher M. Harris, Eric Dominguez, Russell A. Judge, Maria A. Argiriadi, Jennifer DiMauro
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 26:2293-2296
S1P Lyase (SPL) has been described as a drug target in the treatment of autoimmune diseases. It plays an important role in maintaining intracellular levels of S1P thereby affecting T cell egress from lymphoid tissues. Several groups have already publ
Autor:
Ann Edmunds, Dima Rozen, Gabor B. Racz, Miles Day, Leland Lou, Osman A. Latif, Mauricio Orbegozo, Eric Dominguez, Bolkar E. Sahinler, P. Prithvi Raj
Publikováno v:
Pain Practice. 1:344-353
A CSF leak that persists despite conservative therapy may significantly increase the morbidity associated with implantable intrathecal drug delivery systems. This report presents 2 cases where the application of a subdural blood patch led to the sati
Autor:
Hoopfer, Eric Dominguez.
Publikováno v:
May be available electronically.
Thesis (Ph. D.)--Stanford University, 2008.
Submitted to the Program in Neurosciences. Copyright by the author.
Submitted to the Program in Neurosciences. Copyright by the author.
Autor:
Bolkar E. Sahinler, Deeni Bassam, Eric Dominguez, P. Prithvi Raj, Leland Lou, Miles Day, Gabor B. Racz
Publikováno v:
Pain practice : the official journal of World Institute of Pain. 2(4)
This study retrospectively investigated the predictive value of intrathecal narcotic trials for long-term drug utilization via implantable pumps in chronic non-cancer patients. Data were derived from 86 patients who were categorized according to the
Autor:
Eric Dominguez
Publikováno v:
Pain physician. 8(3)
Autor:
Eric Dominguez
Publikováno v:
Regional anesthesia and pain medicine. 26(1)
Background and Objectives The objective of this article is to describe a case of distressing upper extremity phantom limb sensation during intravenous regional anesthesia (IVRA). Case Report A 33-year-old American Society of Anesthesiologists (ASA) s
Autor:
Eric Dominguez
Publikováno v:
Anesthesiology. 91(4)
Autor:
Eric Dominguez
Publikováno v:
Anesthesiology. 93:298-299