Výsledky vyhledávání - "Eric Destexhe"

Akademický článek

Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats

Autor: Camille Planty, Corey P. Mallett, Kevin Yim, Jorge C. G. Blanco, Marina Boukhvalova, Thomas March, Robbert van der Most, Eric Destexhe

Publikováno v: Human Vaccines & Immunotherapeutics, Vol 13, Iss 1, Pp 90-102 (2017)

An increased risk of narcolepsy following administration of an AS03-adjuvanted A(H1N1)pdm09 pandemic influenza vaccine (Pandemrix™) was described in children and adolescents in certain European countries. We investigated the potential effects of ad

Externí odkaz: https://doaj.org/article/25d45cb76b82449aad00af86f237a21c

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Lack of effects on female fertility or pre- and postnatal development of offspring in rats after exposure to AS03-adjuvanted recombinant plant-derived virus-like particle vaccine candidate for COVID-19

Autor: Eric Destexhe, Sarah Paris-Robidas, Charlotte Dubé, Nathalie Landry, Sonia Trépanier, Iryna Primakova, Brian J. Ward

Publikováno v: Reproductive Toxicology (Elmsford, N.y.)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection resulting in the coronavirus disease 2019 (COVID-19) has afflicted tens of millions of people in a worldwide pandemic. A recently developed recombinant Plant-Derived Virus-Like Pa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf32aa4c40e95ebded16735f4c91d8cb
http://europepmc.org/articles/PMC8611889

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Repeated-Dose Toxicity, Biodistribution, and Shedding Assessments With a ChAd155 Respiratory Syncytial Virus Vaccine Candidate Evaluated in Rabbits and Rats

Autor: Alan H. Stokes, Camille Planty, Johanne Pion, Philippe Ancian, Alexandra Rogue, Carine Bansard, Jérémy Silvano, Dominique Papineau, Nawel Ben Abdeljelil, Giulietta Maruggi, Haifeng Song, Catherine Spickler, Karine Blouin, Guillaume Dubois, Luis-Alexander Rodriguez, Judith Baumeister, Ann-Muriel Steff, Eric Destexhe

Publikováno v: INTERNATIONAL JOURNAL OF TOXICOLOGY, 41, 263-275

Respiratory syncytial virus (RSV) is a leading cause of acute lower respiratory tract infections (LRTI) in infants, and toddlers and vaccines are not yet available. A pediatric RSV vaccine (ChAd155-RSV) is being developed to protect infants against R

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d41451c502ad2fec400cba9956b9ee
http://hdl.handle.net/20.500.12470/2779

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Intramuscularly administered herpes zoster subunit vaccine has no effects on fertility, pre- and post-natal development in Sprague-Dawley rats

Autor: Lawrence Segal, Eric Destexhe, Karen Thacker, Nathalie Garçon, Michel Fochesato, Giulia Giordano

Publikováno v: Reproductive Toxicology. 69:297-307

The herpes zoster subunit vaccine (HZ/su) is an investigational vaccine for the prevention of shingles, a disease caused by the varicella zoster virus (VZV). It is composed of recombinant VZV glycoprotein E (gE) and AS01. We assessed the potential to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea468159779da3a8368b547c454d9559
https://doi.org/10.1016/j.reprotox.2017.03.015

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Nonclinical safety assessment of repeated administration and biodistribution of ChAd3-EBO-Z Ebola candidate vaccine

Autor: Marie-Ève Duclos, Camille Planty, Ann-Muriel Steff, Clémentine Chalmey, Guillaume Chevalier, Cécile Sobry, Catherine Thirion-Delalande, Eric Destexhe

Publikováno v: Journal of Applied Toxicology

ChAd3‐EBO‐Z is an investigational adenovirus‐based vaccine for the prevention of Ebola virus disease. Two nonclinical studies were performed to evaluate the biodistribution, local tolerance and potential local and systemic toxic effects of this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48da559e5b9f423405ad3ed5cb14c7aa
https://pubmed.ncbi.nlm.nih.gov/31965598

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Oral Vaccination with Replication-Competent Adenovirus in Mice Reveals Dissemination of the Viral Vaccine beyond the Gastrointestinal Tract

Autor: Carla D. Pretto, Katherine R. Spindler, Justine Javaux, Eric Destexhe, Bénédicte Machiels, Emeline Goffin, Laurent Gillet

Publikováno v: Journal of Virology. 93

Since the 1970s, replication-competent human adenoviruses 4 and 7 have been used as oral vaccines to protect U.S. soldiers against the severe respiratory diseases caused by these viruses. These vaccines are thought to establish a digestive tract infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::366930a42a2dfe14bafacb3983f24cbd
https://doi.org/10.1128/jvi.00237-19

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Evaluation of the potential effects of AS03-adjuvanted A(H1N1)pdm09 vaccine administration on the central nervous system of non-primed and A(H1N1)pdm09-primed cotton rats

Autor: Kevin C. Yim, Corey P. Mallett, Marina S. Boukhvalova, Jorge C. G. Blanco, Thomas H. March, Camille Planty, Eric Destexhe, Robbert van der Most

Publikováno v: Human Vaccines & Immunotherapeutics. 13:90-102

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01a1e3fb33e7314a410f5515e475eb2
https://doi.org/10.1080/21645515.2016.1227518

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Non-clinical safety assessment of single and repeated administration of gE/AS01 zoster vaccine in rabbits

Autor: Lawrence Segal, Eric Destexhe, Nathalie Garçon, Marcel V.W. Wijnands, Menk K. Prinsen, Giulia Giordano

Publikováno v: Journal of Applied Toxicology. 37:132-141

HZ/su is an investigational recombinant subunit vaccine for the prevention of shingles, a disease resulting from the reactivation of varicella zoster virus. The vaccine is composed of recombinant varicella zoster virus glycoprotein E (gE), and liposo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2a6597f21ba7fdf5c6154c30c044166a
https://doi.org/10.1002/jat.3329

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Chimeric hemagglutinin supra-seasonal universal influenza vaccine candidates administered sequentially by the intramuscular route are locally and systemically well-tolerated in rabbits

Autor: Catherine Thirion-Delalande, Corey P. Mallett, Badiaa Bouzya, Ronan N. Rouxel, Eric Destexhe, Emilie Grosdidier, Adèle Bouhraoua, Judith Baumeister

Publikováno v: Regulatory Toxicology and Pharmacology. 113:104625

Sequential intramuscular immunization with chimeric hemagglutinins (cHA) composed of the same conserved HA stalk domain and distinct HA heads is a proposed strategy to produce a supra-seasonal universal influenza vaccine. To evaluate the local tolera

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04d7c69819fd8fdca29997cb531c1731
https://doi.org/10.1016/j.yrtph.2020.104625

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Non-clinical safety assessment of single and repeated intramuscular administration of a human papillomavirus-16/18 vaccine in rabbits and rats

Autor: Kari Kaaber, Eric Destexhe, Danielle Morelle, Nathalie Garçon, Lawrence Segal

Publikováno v: Journal of Applied Toxicology. 35:1577-1585

The human papillomavirus (HPV)-16/18 vaccine (Cervarix®) is a prophylactic vaccine for the prevention of cervical cancer. The vaccine contains recombinant virus-like particles assembled from the L1 major capsid proteins of the cervical cancer-causin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9a15880f513a62b3345bdada45c14c4b
https://doi.org/10.1002/jat.3131

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