Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Eric D. Ross"'
Autor:
Sean M. Cascarina, Eric D. Ross
Publikováno v:
BMC Genomics, Vol 21, Iss 1, Pp 1-18 (2020)
Abstract Background Impaired proteostatic regulation of proteins with prion-like domains (PrLDs) is associated with a variety of human diseases including neurodegenerative disorders, myopathies, and certain forms of cancer. For many of these disorder
Externí odkaz:
https://doaj.org/article/44853bead4bb4ef5923a8064c808f59d
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
The factors regulating stress granule dissolution are not fully understood. Here, the authors identify Sky1 as a stress granule component in yeast, and show that Sky1 kinase activity is required for timely stress granule disassembly during stress rec
Externí odkaz:
https://doaj.org/article/a7152e5c571747a8a63d8a8f489ddb47
Autor:
Sean M Cascarina, Eric D Ross
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 5, p e1011372 (2024)
Low-complexity domains (LCDs) in proteins are typically enriched in one or two predominant amino acids. As a result, LCDs often exhibit unusual structural/biophysical tendencies and can occupy functional niches. However, for each organism, protein se
Externí odkaz:
https://doaj.org/article/ff4ef4e7fac24312b15f70268f460c01
Autor:
Jayantika Bhowmick, Stefania Brocca, Sean M. Cascarina, Soumyanetra Chandra, Limin Chen, Vrushank Davé, Ary Lautaro Di Bartolo, Zsuzsanna Dosztányi, Justin A. Drake, Gábor Erdős, Frank Gondelaud, Kristin D. Graham, Rita Grandori, Munishwar Nath Gupta, Paul M. Harrison, Qiaojing Huang, Luhua Lai, Zhirong Liu, Sonia Longhi, Diego Masone, Antonino Natalello, B. Montgomery Pettitt, Eric D. Ross, Carlo Santambrogio, Antoine Schramm, Jeanne C. Stachowiak, Vladimir N. Uversky, Raghavan Varadarajan, Riley J. Workman, Feng Yuan, Wade F. Zeno
Publikováno v:
Structure and Intrinsic Disorder in Enzymology ISBN: 9780323995337
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9afb6b4b2c9b726213d582323f346fe8
https://doi.org/10.1016/b978-0-323-99533-7.00020-0
https://doi.org/10.1016/b978-0-323-99533-7.00020-0
Autor:
Eric D. Ross, Sean M. Cascarina
Publikováno v:
Structure and Intrinsic Disorder in Enzymology ISBN: 9780323995337
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf153334eee43a6c8a35fba38b3609ac
https://doi.org/10.1016/b978-0-323-99533-7.00014-5
https://doi.org/10.1016/b978-0-323-99533-7.00014-5
Autor:
Sean M Cascarina, Eric D Ross
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 9, p e1006256 (2018)
Proteins with low-complexity domains continue to emerge as key players in both normal and pathological cellular processes. Although low-complexity domains are often grouped into a single class, individual low-complexity domains can differ substantial
Externí odkaz:
https://doaj.org/article/aff29ae5de4c4ac982d847eac0c75bbb
Publikováno v:
PLoS Genetics, Vol 14, Iss 7, p e1007517 (2018)
Enhanced protein aggregation and/or impaired clearance of aggregates can lead to neurodegenerative disorders such as Alzheimer's Disease, Huntington's Disease, and prion diseases. Therefore, many protein quality control factors specialize in recogniz
Externí odkaz:
https://doaj.org/article/5fdf484e657d4106b30f141e8a41150b
Publikováno v:
PLoS Computational Biology, Vol 13, Iss 4, p e1005465 (2017)
Many prion-forming proteins contain glutamine/asparagine (Q/N) rich domains, and there are conflicting opinions as to the role of primary sequence in their conversion to the prion form: is this phenomenon driven primarily by amino acid composition, o
Externí odkaz:
https://doaj.org/article/c079c9989add4b4cb82b07c8399c8729
Autor:
Sean M Cascarina, Eric D Ross
Publikováno v:
Bioinformatics (Oxford, England). 38(24)
Summary Low-complexity domains (LCDs) in proteins are regions enriched in a small subset of amino acids. LCDs exist in all domains of life, often have unusual biophysical behavior, and function in both normal and pathological processes. We recently d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9b3099c8e4954905f801b37ebbeaeca
https://pubmed.ncbi.nlm.nih.gov/36282522
https://pubmed.ncbi.nlm.nih.gov/36282522
Autor:
Sean M. Cascarina, Eric D. Ross
Publikováno v:
RNA (New York, N.Y.). 28(10)
Serine/arginine-rich (SR) proteins comprise a family of proteins that is predominantly found in eukaryotes and plays a prominent role in RNA splicing. A characteristic feature of SR proteins is the presence of an S/R-rich low-complexity domain (RS do
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97fc553647fa7c2a7b35bfbb6e122b36
https://pubmed.ncbi.nlm.nih.gov/35863866
https://pubmed.ncbi.nlm.nih.gov/35863866