Zobrazeno 1 - 10 of 10 pro vyhledávání: '"Eric D. Phelps"'
1
Transgenic Mice Over-Expressing RBP4 Have RBP4-Dependent and Light-Independent Retinal Degeneration
Autor: Rafal Farjo, Laura Otalora, Aaron J Dockins, Krysten M. Farjo, Eric D. Phelps, Jian Xing Ma, Younghwa Shin, Gennadiy Moiseyev, Michael J. Balangue, Shelley Kane, Mei Du
Publikováno v: Investigative Ophthalmology & Visual Science
Purpose Transgenic mice overexpressing serum retinol-binding protein (RBP4-Tg) develop progressive retinal degeneration, characterized by microglia activation, yet the precise mechanisms underlying retinal degeneration are unclear. Previous studies s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45da8a1fa31fb18e53d4db55df5f7ea1
http://europepmc.org/articles/PMC5560100
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2
Inhibition of Stat3 by a Small Molecule Inhibitor Slows Vision Loss in a Rat Model of Diabetic Retinopathy
Autor: Rafal Farjo, Krysten M. Farjo, Jian Xing Ma, Alexander B. Quiambao, R. A. Wassel, Phillip Vanlandingham, Didier J. Nuno, Eric D. Phelps
Publikováno v: Investigative Ophthalmology & Visual Science
Purpose Diabetic retinopathy is a leading cause of vision loss. Previous studies have shown signaling pathways mediated by Stat3 (signal transducer and activator of transcription 3) play a primary role in diabetic retinopathy progression. This study
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::404dde512f2dbe9d4e717ea4a9ad602e
https://pubmed.ncbi.nlm.nih.gov/28395025
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3
Toxoplasma gondiiRhoptry Discharge Correlates with Activation of the Early Growth Response 2 Host Cell Transcription Factor
Autor: Kristin R. Sweeney, Eric D. Phelps, Ira J. Blader
Publikováno v: Infection and Immunity. 76:4703-4712
Toxoplasma gondiiis a ubiquitous apicomplexan parasite that can cause severe disease in fetuses and immune-compromised patients. Rhoptries, micronemes, and dense granules, which are secretory organelles unique toToxoplasmaand other apicomplexan paras
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc999902044dd9cf1a0c17b2bb564213
https://doi.org/10.1128/iai.01447-07
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4
Transcriptional and posttranscriptional regulation of angiopoietin-2 expression mediated by IGF and PDGF in vascular smooth muscle cells
Autor: Elizabeth C. Bullen, Paula Grammas, Eric W. Howard, Dawn L. Updike, Eric D. Phelps
Publikováno v: American Journal of Physiology-Cell Physiology. 290:C352-C361
Angiopoietins play a significant role in vascular development and angiogenesis. Both angiopoietin-1 (Ang1) and angiopoietin-2 (Ang2) bind the receptor tyrosine kinase Tie2. However, while Ang1 signaling results in the stabilization of vessel structur
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f19275a9673f81c1dc65f322b689833
https://doi.org/10.1152/ajpcell.00050.2005
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5
Matrix Metalloproteinases and the Ontogeny of Scarless Repair: The Other Side of the Wound Healing Balance
Autor: Eric W. Howard, Dawn L. Updike, Ziv M. Peled, Thomas M. Krummel, James Chang, Eric D. Phelps, Michael T. Longaker
Publikováno v: Plastic and Reconstructive Surgery. 110:801-811
Early gestation mammalian fetuses possess the remarkable ability to heal cutaneous wounds in a scarless fashion. Over the past 20 years, scientists have been working to decipher the mechanisms underlying this phenomenon. Much of the research to date
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19de3456765a56c4ad1bb2ea92a62714
https://doi.org/10.1097/01.prs.0000019915.20203.ec
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6
Gelatinase A expression in endothelial cells is regulated by at least two cis-acting promoter elements
Autor: Thien Khai H Vu, Eric W. Howard, Eric D. Phelps, Kurt D. Bottles, Paula Grammas, Elizabeth C. Bullen, Dawn L. Updike
Publikováno v: Biochimica et Biophysica Acta (BBA) - General Subjects. 1428:147-160
Increased expression of gelatinase A is associated with both angiogenesis and alterations in blood vessel structure. Heart-derived endothelial cells derived from spontaneously hypertensive rats (SHR) were found to express significantly more gelatinas
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5700fc93e6907a58081086445f618805
https://doi.org/10.1016/s0304-4165(99)00059-8
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8
Serum response factor regulates immediate early host gene expression in Toxoplasma gondii-infected host cells
Autor: Crystal Teygong, Ira J. Blader, Mandi Wiley, Jay R. Radke, Eric D. Phelps
Publikováno v: PLoS ONE, Vol 6, Iss 3, p e18335 (2011)
PLoS ONE
Toxoplasma gondii is a wide spread pathogen that can cause severe and even fatal disease in fetuses and immune-compromised hosts. As an obligate intracellular parasite, Toxoplasma must alter the environment of its host cell in order to establish its
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806ed91ca866ae75ddbd1af3582ab7a1
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21479245/pdf/?tool=EBI
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9
The Role of Endogenous Epidermal Growth Factor Receptor Ligands in Mediating Corneal Epithelial Homeostasis
Autor: Brian P. Ceresa, Shlomit Schaal, Eric D. Phelps, Mark A. Doll, Joanne L Peterson
Publikováno v: Investigative Opthalmology & Visual Science. 55:2870
Purpose To provide a comprehensive study of the biological role and therapeutic potential of six endogenous epidermal growth factor receptor (EGFR) ligands in corneal epithelial homeostasis. Methods Kinetic analysis and dose response curves were perf
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbd1e9eb77c7385b9749f665ebbd646
https://doi.org/10.1167/iovs.13-12943
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