Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Eric D. Laywell"'
Autor:
Lindsay H. Levkoff, Gregory P. Marshall, II, Heather H. Ross, Maria Caldeira, Brent A. Reynolds, Meryem Cakiroglu, Christopher L. Mariani, Wolfgang J. Streit, Eric D. Laywell
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 10, Iss 8, Pp 804-816 (2008)
The thymidine analog bromodeoxyuridine (BrdU) is incorporated into newly synthesized DNA and has been shown to increase the susceptibility of incorporating cells to ionizing radiation. However, in the absence of secondary stressors, BrdU is thought t
Externí odkaz:
https://doaj.org/article/7c34ec796c5a42438bc478b260b803b1
Autor:
David D. Fuller, Alexander J. Tiemeier, Heather H. Ross, Eric D. Laywell, Garrett Fitzpatrick, Tina F. Cheung, Milap S Sandhu, Warren J. Sher
Publikováno v:
Experimental Neurology. 235:238-245
In vitro exposure of neural progenitor cell (NPC) populations to reduced O(2) (e.g. 3% versus 20%) can increase their proliferation, survival and neuronal differentiation. Our objective was to determine if an acute (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e81289b84edf14d0eab92cedc4a9eb
https://doi.org/10.1016/j.expneurol.2012.01.027
https://doi.org/10.1016/j.expneurol.2012.01.027
Publikováno v:
Glia. 56:1799-1808
Microglia, the resident immune cells of the brain, have recently been hypothesized to play a role both in neuronal diseases and age related neurogenic decline, and are theorized to be modulators of adult neurogenesis. Current methods for the isolatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2c056c0ca8dd9ced7c9746c0664aa6a
https://doi.org/10.1002/glia.20730
https://doi.org/10.1002/glia.20730
Autor:
Eric D. Laywell, Meryem Demir
Publikováno v:
Frontiers in Neuroscience, Vol 9 (2015)
Frontiers in Neuroscience
Frontiers in Neuroscience
Azidothymidine (AZT) is a synthetic, chain-terminating nucleoside analog used to treat HIV-1 infection. While AZT is not actively transported across the blood brain barrier, it does accumulate at high levels in cerebrospinal fluid, and subsequently d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c590be025189ed462fcea2447c38c5
http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00093/full
http://journal.frontiersin.org/Journal/10.3389/fnins.2015.00093/full
Publikováno v:
Stem Cells. 24:1054-1064
Reports of neural transdifferentiation of mesenchymal stem cells (MSCs) suggest the possibility that these cells may serve as a source for stem cell–based regenerative medicine to treat neurological disorders. However, some recent studies controver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27be0430f06e946565664ebe472d411e
https://doi.org/10.1634/stemcells.2005-0370
https://doi.org/10.1634/stemcells.2005-0370
Publikováno v:
Stem Cells. 24:731-738
Hematopoietic stem cells have been defined by their ability to self-renew and successfully reconstitute hematopoiesis throughout the life of a transplant recipient. Neural stem cells (NSCs) are believed to exist in the regenerating regions of the bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a6b2da77c4ffe6be6a09988c7a90fb5
https://doi.org/10.1634/stemcells.2005-0245
https://doi.org/10.1634/stemcells.2005-0245
Publikováno v:
STEM CELLS. 23:1276-1285
The subependymal zone (SEZ) is a region of persistent neurogenesis in the adult mammalian brain containing a neural stem cell (NSC) pool that continuously generates migratory neuroblasts that travel in chains through the rostral migratory stream (RMS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbeaa103bb3afb3cbdead2e25b25f7d
https://doi.org/10.1634/stemcells.2005-0073
https://doi.org/10.1634/stemcells.2005-0073
Autor:
Eric D. Laywell, Dennis A. Steindler, Renata Sano, Alessandra d'Azzo, Alessandra Tessitore, Yanjun Ma, Maria del Pilar Martin, Linda M. Hendershot, Angela Ingrassia, Linda Mann
Publikováno v:
Molecular Cell. 15(5):753-766
GM1-ganglioside (GM1) is a major sialoglycolipid of neuronal membranes that, among other functions, modulates calcium homeostasis. Excessive accumulation of GM1 due to deficiency of lysosomal beta-galactosidase (beta-gal) characterizes the neurodegen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e042228fd21106f85ea24378a71dd224
Autor:
Anthony T. Yachnis, Edward W. Scott, John R. Wingard, Christopher R. Cogle, Eric D. Laywell, Dennis A. Steindler, Dani S. Zander
Publikováno v:
The Lancet. 363:1432-1437
Summary Background End-organ repair by adult haemopoietic stem cells is under great scrutiny with investigators challenging the notion of these cells' plasticity. Some investigations of animals and short-term human bone marrow transplants suggest tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35fcbd58a83b4b8cb2cd7e61344f81ab
https://doi.org/10.1016/s0140-6736(04)16102-3
https://doi.org/10.1016/s0140-6736(04)16102-3
Publikováno v:
Experimental Neurology. 182:240-244
There is a paucity of information on the roles of extracellular matrix (ECM) and substrate molecules in general with regard to the growth and differentiation of neural stem and progenitor cells. There are well-established findings of a dense, presuma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e31cc121579e57efa6092c673b8eb651
https://doi.org/10.1016/s0014-4886(03)00124-9
https://doi.org/10.1016/s0014-4886(03)00124-9