Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Eric D Crown"'
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
The spinal cord demonstrates several forms of plasticity that resemble brain-dependent learning and memory. Among the most studied form of spinal plasticity is spinal memory for noxious (nociceptive) stimulation. Numerous papers have described centra
Externí odkaz:
https://doaj.org/article/c1a4b6e98f3f46948ba6a01a886808f1
Autor:
Adam R Ferguson, J Russell eHuie, Eric D Crown, Kyle M Baumbauer, Michelle A Hook, Sandra M Garraway, Kuan H Lee, Kevin C Hoy, James W Grau
Publikováno v:
Frontiers in Physiology, Vol 3 (2012)
Synaptic plasticity within the spinal cord has great potential to facilitate recovery of function after spinal cord injury (SCI). Spinal plasticity can be induced in an activity-dependent manner even without input from the brain after complete SCI. T
Externí odkaz:
https://doaj.org/article/5ee50337a7f24eb192040b1b3c968f21
Autor:
Jeong Heo, Yoon Jun Kim, Jin-Woo Lee, Ji Hoon Kim, Young-Suk Lim, Kwang-Hyub Han, Sook-Hyang Jeong, Mong Cho, Ki Tae Yoon, Si Hyun Bae, Eric D. Crown, Linda M. Fredrick, Negar Niki Alami, Armen Asatryan, Do Hyun Kim, Seung Woon Paik, Youn-Jae Lee
Publikováno v:
Gut and Liver, Vol 15, Iss 6, Pp 895-903 (2021)
Background/Aims: Glecaprevir/pibrentasvir (G/P) is the first pan-genotypic direct-acting antiviral combination therapy approved in Korea. An integrated analysis of five phase II and III trials was conducted to evaluate the efficacy and safety of G/P
Externí odkaz:
https://doaj.org/article/5090ec51a94c495aa641491335e33b4f
Autor:
David J. McAdoo, Young Seob Gwak, Eric D. Crown, Huai Yu Tan, Zaiming Ye, Kathia M. Johnson, Claire E. Hulsebosch, Guo Ying Xu
Publikováno v:
Pain. 153:710-721
Chronic central neuropathic pain after central nervous system injuries remains refractory to therapeutic interventions. A novel approach would be to target key intracellular signaling proteins that are known to contribute to continued activation by p
Publikováno v:
Experimental Neurology. 213:257-267
Recent work regarding chronic central neuropathic pain (CNP) following spinal cord injury (SCI) suggests that activation of key signaling molecules such as members of the mitogen activated protein kinase (MAPK) family play a role in the expression of
Autor:
J.R. Huie, Zhe Ying, Adam R. Ferguson, Kyle M. Baumbauer, V. R. Edgerton, Eric D. Crown, James W. Grau, Fernando Gomez-Pinilla
Publikováno v:
Neuroscience. 148:893-906
We have previously shown that the spinal cord is capable of learning a sensorimotor task in the absence of supraspinal input. Given the action of brain-derived neurotrophic factor (BDNF) on hippocampal learning, the current studies examined the role
Autor:
Eric D. Crown, James W. Grau, Michelle A. Hook, Rajesh C. Miranda, Stephanie N. Washburn, Adam R. Ferguson
Publikováno v:
Behavioral and Cognitive Neuroscience Reviews. 5:191-239
Using spinally transected rats, research has shown that neurons within the L4-S2 spinal cord are sensitive to response-outcome (instrumental) relations. This learning depends on a form of N-methyl-D-aspartate (NMDA)-mediated plasticity. Instrumental
Autor:
Guo Ying Xu, Zaiming Ye, Claire E. Hulsebosch, Kathia M. Johnson, Eric D. Crown, David J. McAdoo
Publikováno v:
Experimental Neurology. 199:397-407
Rats given moderate spinal cord injury (SCI) display increases in the expression of the activated form of the transcription factor cyclic AMP responsive element binding protein (CREB) in spinal segments of dermatomes corresponding to permanent mechan
Publikováno v:
Neuroscience. 141:421-431
Spinal plasticity is known to play a role in central neurogenic pain. Over the last 100 years researchers have found that the spinal cord is also capable of supporting other forms of plasticity including several forms of learning. To study instrument
Autor:
Karin N. Westlund, Kathia M. Johnson, Zaiming Ye, Guo-Ying Xu, David J. McAdoo, Eric D. Crown, Claire E. Hulsebosch
Publikováno v:
Neuroscience Letters. 384:139-144
Spinal cord injury (SCI) often leads to the generation of chronic intractable neuropathic pain. The mechanisms that lead to chronic central neuropathic pain (CNP) following SCI are not well understood, resulting in ineffective treatments for pain rel