Zobrazeno 1 - 10
of 300
pro vyhledávání: '"Eric D Brown"'
Publikováno v:
PLoS Genetics, Vol 19, Iss 11, p e1011013 (2023)
Exposure of Escherichia coli to sub-inhibitory antibiotics stimulates biofilm formation through poorly characterized mechanisms. Using a high-throughput Congo Red binding assay to report on biofilm matrix production, we screened ~4000 E. coli K12 del
Externí odkaz:
https://doaj.org/article/219b9c932b9c436894edc9f73b9e9b6f
Autor:
Michele D Kattke, Jason E Gosschalk, Orlando E Martinez, Garima Kumar, Robert T Gale, Duilio Cascio, Michael R Sawaya, Martin Philips, Eric D Brown, Robert T Clubb
Publikováno v:
PLoS Pathogens, Vol 15, Iss 4, p e1007723 (2019)
Staphylococcus aureus and other bacterial pathogens affix wall teichoic acids (WTAs) to their surface. These highly abundant anionic glycopolymers have critical functions in bacterial physiology and their susceptibility to β-lactam antibiotics. The
Externí odkaz:
https://doaj.org/article/7f0a8bf7318548a9bcafd1c36499c5bd
Autor:
Solmaz Sobhanifar, Liam J Worrall, Dustin T King, Gregory A Wasney, Lars Baumann, Robert T Gale, Michael Nosella, Eric D Brown, Stephen G Withers, Natalie C J Strynadka
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006067 (2016)
In recent years, there has been a growing interest in teichoic acids as targets for antibiotic drug design against major clinical pathogens such as Staphylococcus aureus, reflecting the disquieting increase in antibiotic resistance and the historical
Externí odkaz:
https://doaj.org/article/5145b8a01c064e478e04e7f807981379
Autor:
Carrie Selin, Maria S Stietz, Jan E Blanchard, Sebastian S Gehrke, Sylvain Bernard, Dennis G Hall, Eric D Brown, Silvia T Cardona
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0128587 (2015)
Infections with the bacteria Burkholderia cepacia complex (Bcc) are very difficult to eradicate in cystic fibrosis patients due the intrinsic resistance of Bcc to most available antibiotics and the emergence of multiple antibiotic resistant strains d
Externí odkaz:
https://doaj.org/article/bcb06f888bb44a0291f99ee9d0b040fe
Publikováno v:
eLife, Vol 3 (2014)
While small molecule inhibitors of the bacterial ribosome have been instrumental in understanding protein translation, no such probes exist to study ribosome biogenesis. We screened a diverse chemical collection that included previously approved drug
Externí odkaz:
https://doaj.org/article/982dfdbcd6d44e7b9da7f2e773f30624
Autor:
Lindsey A. Carfrae, Eric D. Brown
Publikováno v:
Trends in Microbiology. 31:571-585
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e989a8c0762f8ee8293b95fbbce1276c
https://doi.org/10.1016/j.tim.2023.01.002
https://doi.org/10.1016/j.tim.2023.01.002
Autor:
Noor Abu Jarad, Kenneth Rachwalski, Fereshteh Bayat, Shadman Khan, Amid Shakeri, Roderick MacLachlan, Martin Villegas, Eric D. Brown, Zeinab Hosseinidoust, Tohid F. Didar, Leyla Soleymani
Publikováno v:
ACS Applied Materials & Interfaces. 15:16253-16265
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5855b0b5974b304dbeac62f514a940b
https://doi.org/10.1021/acsami.2c23119
https://doi.org/10.1021/acsami.2c23119
Autor:
Kristina Klobucar, Emily Jardine, Maya A. Farha, Marc R. MacKinnon, Meghan Fragis, Brenda Nkonge, Timsy Bhando, Louis Borrillo, Caressa N. Tsai, Jarrod W. Johnson, Brian K. Coombes, Jakob Magolan, Eric D. Brown
Publikováno v:
ACS Infectious Diseases. 8:2187-2197
Gram-negative bacteria are intrinsically resistant to a plethora of antibiotics that effectively inhibit the growth of Gram-positive bacteria. The intrinsic resistance of Gram-negative bacteria to classes of antibiotics, including rifamycins, aminoco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f634e3730d232d4470b6318d1f9197
https://doi.org/10.1021/acsinfecdis.2c00357
https://doi.org/10.1021/acsinfecdis.2c00357
Autor:
Lindsey A. Carfrae, Kenneth Rachwalski, Shawn French, Rodion Gordzevich, Laura Seidel, Caressa N. Tsai, Megan M. Tu, Craig R. MacNair, Olga G. Ovchinnikova, Bradley R. Clarke, Chris Whitfield, Eric D. Brown
Publikováno v:
Nature Microbiology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81d6b82e52a7bb6a76e755becb078789
https://doi.org/10.1038/s41564-023-01369-z
https://doi.org/10.1038/s41564-023-01369-z
SummaryOrdered collections of precise gene deletions inE. coliand other model microbes have proven to be invaluable resources to study the dispensability of the non-essential genome in different environmental and genetic contexts. The dispensability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::66e67a9ab9fa300ed29a66614d9a1886
https://doi.org/10.1101/2023.04.21.537703
https://doi.org/10.1101/2023.04.21.537703
