Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Eric Colman"'
Autor:
Andrew D. Mosholder, Jonathan G. Levine, Jo Wyeth, Eric Colman, Devanand Jillapalli, Mark I. Avigan, Ana Szarfman
Publikováno v:
Pharmacoepidemiology and Drug Safety. 17:1068-1076
SUMMARY Background We detected disproportionate reporting of amyotrophic lateral sclerosis (ALS) with HMG-CoA-reductase inhibitors (statins) in the Food and Drug Administration’s (FDA) spontaneous adverse event (AE) reporting system (AERS). Purpose
Publikováno v:
New England Journal of Medicine. 367:1577-1579
After weighing the risks and benefits, the FDA recently approved two new drugs as adjuncts to a reduced-calorie diet and increased physical activity for chronic weight management in obese or overweight adults with at least one weight-related coexisti
Autor:
Eric Colman, Amy Egan
Publikováno v:
New England Journal of Medicine. 365:285-287
Having reviewed the data on the risk of myopathy, the FDA recommends that the 80-mg dose of simvastatin be used only in patients who have been taking this dose for an extended period without signs or symptoms of clinically significant muscle toxicity
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 270:E72-E78
This study determines whether there are regional differences in lipolysis and whether adipocyte lipolysis is associated with the degree of visceral adiposity and its metabolic complications in 32 obese (28-37 kg/m2), nondiabetic, postmenopausal women
Autor:
Patricia J. Coon, Susan Engelhardt, Leslie I. Katzel, Ellen M. Rogus, John D. Sorkin, Andrew P. Goldberg, Eric Colman
Publikováno v:
Experimental Gerontology. 30:571-580
The prevalence of impaired glucose tolerance (IGT) increases with aging. Although some data suggest that age is independently associated with IGT, other studies suggest that age-associated changes in body composition and reduced cardiovascular fitnes
Autor:
Eric Colman
Publikováno v:
Circulation. 125(17)
An estimated 70% of adult men and 60% of adult women in the United States are overweight or obese.1 Excess body fat increases the likelihood of developing hypertension, dyslipidemia, and type 2 diabetes mellitus and is an independent risk factor for
Autor:
M.Janette Busby-Whitehead, Loretta E. Lakatta, Edward G. Lakatta, Lewis C. Becker, Jerome L. Fleg, Eric Colman, Leslie I. Katzel, John D. Sorkin, Andrew P. Goldberg
Publikováno v:
The American Journal of Cardiology. 74:869-874
This study determined the risk factors for exercise-induced silent ischemia (SI) in 281 apparently healthy volunteers aged 40 to 87 years and compared their risk factor profiles with those of 132 patients with overt coronary artery disease (CAD). SI
Autor:
Eric Colman
Publikováno v:
The Lancet. 354:324-326
Autor:
Eric Colman
Publikováno v:
Annals of internal medicine. 143(5)
Beginning with the passage of the Federal Food, Drug, and Cosmetic Act in 1938 and escalating with the 1962 Kefauver-Harris amendments, increasing pressure has been placed on pharmaceutical manufacturers to demonstrate that a drug's benefits outweigh
Autor:
Eric Colman
Publikováno v:
Journal of medical biography. 12(4)
Fielding Hudson Garrison once remarked that because his birthday fell on 5 November, Guy Fawkes Day, he was “fated to suffer from in-ward hell-fire and brimstone all [his] life”. Though said in jest, Garrison was a vulnerable, melancholic and sel