Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Eric Camerer"'
Autor:
Randall C. Gunther, Vanthana Bharathi, Stephen D. Miles, Lauryn R. Tumey, Clare M. Schmedes, Kohei Tatsumi, Meagan D. Bridges, David Martinez, Stephanie A. Montgomery, Melinda A. Beck, Eric Camerer, Nigel Mackman, Silvio Antoniak
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundInnate immune responses to influenza A virus (IAV) infection are initiated in part by toll-like receptor 3 (TLR3). TLR3-dependent signaling induces an antiviral immune response and an NFκB-dependent inflammatory response. Protease-activate
Externí odkaz:
https://doaj.org/article/9ce01fde26334c13975a5e0be80b3539
Autor:
Hélène Lazareth, Carole Henique, Olivia Lenoir, Victor G. Puelles, Martin Flamant, Guillaume Bollée, Cécile Fligny, Marine Camus, Lea Guyonnet, Corinne Millien, François Gaillard, Anna Chipont, Blaise Robin, Sylvie Fabrega, Neeraj Dhaun, Eric Camerer, Oliver Kretz, Florian Grahammer, Fabian Braun, Tobias B. Huber, Dominique Nochy, Chantal Mandet, Patrick Bruneval, Laurent Mesnard, Eric Thervet, Alexandre Karras, François Le Naour, Eric Rubinstein, Claude Boucheix, Antigoni Alexandrou, Marcus J. Moeller, Cédric Bouzigues, Pierre-Louis Tharaux
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
In both focal segmental glomerulosclerosis (FSGS) and crescentic glomerulonephritis (CGN), kidney injury is characterised by the invasion of glomerular tufts by parietal epithelial cells (PECs). Here Lazareth et al. identify the tetraspanin CD9 as a
Externí odkaz:
https://doaj.org/article/b682a5c3bcb44d6ba72e2b6a4e2372c3
Autor:
Timo Buhl, Akihiko Ikoma, Cordula Kempkes, Ferda Cevikbas, Mathias Sulk, Joerg Buddenkotte, Tasuku Akiyama, Debbie Crumrine, Eric Camerer, Earl Carstens, Michael P. Schön, Peter Elias, Shaun R. Coughlin, Martin Steinhoff
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Background: Activation of protease-activated receptor-2 (PAR2) has been implicated in inflammation, pruritus, and skin barrier regulation, all characteristics of atopic dermatitis (AD), as well as Netherton syndrome which has similar characteristics.
Externí odkaz:
https://doaj.org/article/c5bb5fb6a4bb4f2d83da1602d401752c
Autor:
Eric Engelbrecht, Michel V Levesque, Liqun He, Michael Vanlandewijck, Anja Nitzsche, Hira Niazi, Andrew Kuo, Sasha A Singh, Masanori Aikawa, Kristina Holton, Richard L Proia, Mari Kono, William T Pu, Eric Camerer, Christer Betsholtz, Timothy Hla
Publikováno v:
eLife, Vol 9 (2020)
Despite the medical importance of G protein-coupled receptors (GPCRs), in vivo cellular heterogeneity of GPCR signaling and downstream transcriptional responses are not understood. We report the comprehensive characterization of transcriptomes (bulk
Externí odkaz:
https://doaj.org/article/2b95d8d5a479422885261efe96819fc7
Autor:
Stine Friis, Daniel Tadeo, Sylvain M. Le-Gall, Henrik Jessen Jürgensen, Katiuchia Uzzun Sales, Eric Camerer, Thomas H. Bugge
Publikováno v:
BMC Biology, Vol 15, Iss 1, Pp 1-17 (2017)
Abstract Background Matriptase is a membrane serine protease essential for epithelial development, homeostasis, and regeneration, as well as a central orchestrator of pathogenic pericellular signaling in the context of inflammatory and proliferative
Externí odkaz:
https://doaj.org/article/96b236299cf5401b81b37fb6c67c3c7b
Publikováno v:
PLoS Genetics, Vol 10, Iss 7, p e1004470 (2014)
The development of eutherian mammalian embryos is critically dependent on the selective bi-directional transport of molecules across the placenta. Here, we uncover two independent and partially redundant protease signaling pathways that include the m
Externí odkaz:
https://doaj.org/article/d640fb5de5074cefa0ceb6170e674ca5
Autor:
Fatma Berri, Guus F Rimmelzwaan, Michel Hanss, Emmanuel Albina, Marie-Laure Foucault-Grunenwald, Vuong B Lê, Stella E Vogelzang-van Trierum, Patrica Gil, Eric Camerer, Dominique Martinez, Bruno Lina, Roger Lijnen, Peter Carmeliet, Béatrice Riteau
Publikováno v:
PLoS Pathogens, Vol 9, Iss 3, p e1003229 (2013)
Detrimental inflammation of the lungs is a hallmark of severe influenza virus infections. Endothelial cells are the source of cytokine amplification, although mechanisms underlying this process are unknown. Here, using combined pharmacological and ge
Externí odkaz:
https://doaj.org/article/9f9c69898aa84d7dba0eade89776cc72
Autor:
Roman Szabo, Katiuchia Uzzun Sales, Peter Kosa, Natalia A Shylo, Sine Godiksen, Karina K Hansen, Stine Friis, J Silvio Gutkind, Lotte K Vogel, Edith Hummler, Eric Camerer, Thomas H Bugge
Publikováno v:
PLoS Genetics, Vol 8, Iss 8, p e1002937 (2012)
Loss of either hepatocyte growth factor activator inhibitor (HAI)-1 or -2 is associated with embryonic lethality in mice, which can be rescued by the simultaneous inactivation of the membrane-anchored serine protease, matriptase, thereby demonstratin
Externí odkaz:
https://doaj.org/article/9de82db345fb45cea6db9244198f55ad
Autor:
Pierre Nivoit, Thomas Mathivet, Junxi Wu, Yann Salemkour, Devanarayanan Siva Sankar, Véronique Baudrie, Jennifer Bourreau, Anne-Laure Guihot, Emilie Vessières, Mathilde Lemitre, Cinzia Bocca, Jérémie Teillon, Morgane Le Gall, Anna Chipont, Estelle Robidel, Neeraj Dhaun, Eric Camerer, Pascal Reynier, Etienne Roux, Thierry Couffinhal, Patrick Hadoke, Jean-sébastien Silvestre, Xavier Guillonneau, Philippe Bonnin, Daniel Henrion, Jörn Dengjel, Pierre-Louis Tharaux, Olivia Lenoir
Dysregulated autophagy is associated with cardiovascular and metabolic diseases, where impaired flow-mediated endothelial cell responses promote cardiovascular risk. The mechanism by which the autophagy machinery regulates endothelial functions is co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c237327fa47b8078f174921ac2ebec32
https://doi.org/10.21203/rs.3.rs-2276541/v1
https://doi.org/10.21203/rs.3.rs-2276541/v1
Autor:
Ilaria Del Gaudio, Eric Camerer
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology
Arteriosclerosis, Thrombosis, and Vascular Biology, 2022, 42 (7), pp.903-905. ⟨10.1161/ATVBAHA.122.317794⟩
Arterioscler Thromb Vasc Biol
Arteriosclerosis, Thrombosis, and Vascular Biology, 2022, 42 (7), pp.903-905. ⟨10.1161/ATVBAHA.122.317794⟩
Arterioscler Thromb Vasc Biol
BACKGROUND: The vascular endothelium maintains tissue-fluid homeostasis by controlling the passage of large molecules and fluid between the blood and interstitial space. The interaction of catenins and the actin cytoskeleton with vascular endothelial