Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Eric C. Svensson"'
Autor:
Eric C. Svensson, Anne-Marie Martin, Paul M. Ridker, Margaret Dugan, Lynne Krajkovich, Margaret F. Prescott, Xiaoshan Wang, Ying A. Wang, Siyan Xu, Bharani Bharani-Dharan, Michael T. Beste, Angela Silvestro, Jason Baum, Connie C. Wong
In the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS), inhibition of the IL1β inflammatory pathway by canakinumab has been shown to significantly reduce lung cancer incidence and mortality. Here we performed molecular characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e41244aa22ed2b76984f9688149a8ca
https://doi.org/10.1158/0008-5472.c.6511695
https://doi.org/10.1158/0008-5472.c.6511695
Autor:
Eric C. Svensson, Anne-Marie Martin, Paul M. Ridker, Margaret Dugan, Lynne Krajkovich, Margaret F. Prescott, Xiaoshan Wang, Ying A. Wang, Siyan Xu, Bharani Bharani-Dharan, Michael T. Beste, Angela Silvestro, Jason Baum, Connie C. Wong
Supplementary Data
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4345f3f0dd602cc5da0899311013767b
https://doi.org/10.1158/0008-5472.22424148
https://doi.org/10.1158/0008-5472.22424148
Autor:
Eric C. Svensson, Paul M. Ridker, Jason Baum, Bharani Bharani-Dharan, Ying A Wang, Siyan Xu, Xiaoshan Wang, Anne-Marie Martin, Margaret F. Prescott, Margaret Dugan, Michael T. Beste, Angela Silvestro, Wong Connie C, Lynne Krajkovich
Publikováno v:
Cancer Research. 80:5597-5605
In the Canakinumab Anti-inflammatory Thrombosis Outcomes Study (CANTOS), inhibition of the IL1β inflammatory pathway by canakinumab has been shown to significantly reduce lung cancer incidence and mortality. Here we performed molecular characterizat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff54765101fd231d47e4a722f68d46b8
https://doi.org/10.1158/0008-5472.can-19-3176
https://doi.org/10.1158/0008-5472.can-19-3176
Autor:
Eric C. Svensson, Aviv Madar, Catarina D. Campbell, Yunsheng He, Marc Sultan, Margaret L. Healey, Huilei Xu, Katie D’Aco, Anita Fernandez, Clarisse Wache-Mainier, Peter Libby, Paul M. Ridker, Michael T. Beste, Craig T. Basson
Publikováno v:
JAMA Cardiol
IMPORTANCE: Clonal hematopoiesis of indeterminate potential (CHIP) is associated with increased risk of atherosclerotic cardiovascular disease, and mouse experiments suggest that CHIP related to Tet2 loss of function in myeloid cells accelerates athe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cce54c4131c15b2f4df5eb40e5a5fee8
https://europepmc.org/articles/PMC8988022/
https://europepmc.org/articles/PMC8988022/
Autor:
Claudia Hon, Ma’en Obeidat, Jason M. Laramie, Philippe Marc, Pablo Serrano-Fernandez, Paul M. Ridker, Margaret L Healey, Michael T. Beste, Arkady I Gusev, Aviv Madar, Huilei Xu, Nicole Hartmann, Denise Yates, Scott Kennedy, Sergio Kaiser, Eric C. Svensson
Publikováno v:
Circulation: Genomic and Precision Medicine. 14
No formal abstract in format we plan to submit to journal (a short report). Informally, the work presented here adds to a body of evidence that shows how polygenic risk scores (PRS) for coronary artery disease (CAD) can be used to inform on patient's
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19417bb8b0b5ac6a5dcd436b2108d314
https://doi.org/10.1161/circgen.121.003440
https://doi.org/10.1161/circgen.121.003440
Autor:
Elizabeth M. McNally, Ivan P. Moskowitz, Christopher R. Weber, Carlos Perez-Cervantes, Stefan R Mazurek, Jeff Steimle, Kohta Ikegami, Eric C. Svensson, Brigitte Laforest, Michael Broman, Sonja Lazaveric, William T. Pu, Rangarajan D. Nadadur, Xinan Yang, Linsin A Smith
Publikováno v:
Circulation Research. 129
Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting over 33 million individuals throughout the world. AF is highly heritable and recent genome-wide association studies (GWAS) have cumulatively identified over 100 loci associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::06ec63dc16a51c021f1cc3ae793fa766
https://doi.org/10.1161/res.129.suppl_1.mp208
https://doi.org/10.1161/res.129.suppl_1.mp208
Autor:
Lee Ann Garrett-Sinha, Justin Dalton, Alifa Stith, Katherine Sortino, Sarah Metcalfe, David Goich, Eric C. Svensson, Alex Sunshine
Publikováno v:
ImmunoHorizons
Ets1 is emerging as a key transcription factor that is required to prevent autoimmunity in mice and humans. Ets1 is expressed in both B and T cells, and mice lacking Ets1 are characterized by excess B and T cell activation, leading to enhanced format
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d3aad2d8695264bb239e562c9d9c87c
http://europepmc.org/articles/PMC7008956
http://europepmc.org/articles/PMC7008956
Abstract 550: FOG2 Modulates a TBX5-Dependent Gene Regulatory Network for Cardiac Rhythm Homeostasis
Autor:
Carlos Perez-Cervantes, Brigitte Laforest, Ivan P. Moskowitz, Eric C. Svensson, Christopher R. Weber, Kaitlyn M Shen, Sonja Lazarevic, Michael Broman, Kohta Ikegami, Xinan Yang, Rangarajan D. Nadadur, Margaret Gadek, Stefan R Mazurek, Jeff Steimle
Publikováno v:
Circulation Research. 127
Atrial fibrillation (AF) is the most common cardiac arrhythmia. Recent work has implicated numerous transcription factors in AF risk, including ZFPM2 (FOG2), GATA4, and TBX5. FOG2 is overexpressed in human heart failure, a major AF risk factor. We fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c0612fbbd8d3f3301bfa9aa120ce49ef
https://doi.org/10.1161/res.127.suppl_1.550
https://doi.org/10.1161/res.127.suppl_1.550
Publikováno v:
PLoS ONE, Vol 4, Iss 7, p e6161 (2009)
MicroRNAs are increasingly being recognized as regulators of embryonic development; however, relatively few microRNAs have been identified to regulate cardiac development. FOG-2 (also known as zfpm2) is a transcriptional co-factor that we have previo
Externí odkaz:
https://doaj.org/article/d74eea2cf973431cb0ac239a89427dee
Autor:
Stuart H Cole, Alana Althage, Xiaohan Xu, Shifeng Pan, Peter Gergely, Jörg H W Distler, Eric C. Svensson, Chun Li, Jennifer L. Harris, Christiane Maier, H. Martin Seidel, Nicholas Ng, Mindy H. Hsieh, Georg Schett, Jun Liu, Chih-Wei Chen, Thuong Trinh-Minh, Christian Beyer, Shelly Meeusen
Publikováno v:
Annals of the Rheumatic Diseases. 76:773-778
ObjectivesWnt signalling has been implicated in activating a fibrogenic programme in fibroblasts in systemic sclerosis (SSc). Porcupine is an O-acyltransferase required for secretion of Wnt proteins in mammals. Here, we aimed to evaluate the antifibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1df10048412b094c49ab3e342e4081c
https://doi.org/10.1136/annrheumdis-2016-210294
https://doi.org/10.1136/annrheumdis-2016-210294