Zobrazeno 1 - 10
of 135
pro vyhledávání: '"Eric C. Schirmer"'
Autor:
Eric C. Schirmer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/0f7032cc594c47a1a4b7b1e56e3094cb
Autor:
Eric C. Schirmer, Joanna M. Bridger
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/091feb11a2ce48baa5e6158d0e578db7
Autor:
Andrea Rizzotto, Sylvain Tollis, Nhan T. Pham, Yijing Zheng, Maria Alba Abad, Jan Wildenhain, A. Arockia Jeyaprakash, Manfred Auer, Mike Tyers, Eric C. Schirmer
Publikováno v:
Cells, Vol 13, Iss 1, p 57 (2023)
Increased nuclear size correlates with lower survival rates and higher grades for prostate cancer. The short-chain dehydrogenase/reductase (SDR) family member DHRS7 was suggested as a biomarker for use in prostate cancer grading because it is largely
Externí odkaz:
https://doaj.org/article/ac36edf31ab54a338b9f8da30a7b02e4
Autor:
Rafal Czapiewski, Dzmitry G. Batrakou, Jose I. de las Heras, Roderick N. Carter, Aishwarya Sivakumar, Magdalena Sliwinska, Charles R. Dixon, Shaun Webb, Giovanna Lattanzi, Nicholas M. Morton, Eric C. Schirmer
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Little is known how spatial genome organization is directed in fat; however, key proadipogenic genes reposition from the nuclear envelope (NE) to the interior during adipogenesis. Here the authors show that deletion of NE protein Tmem120a in adipocyt
Externí odkaz:
https://doaj.org/article/5efba97324ba4758897fa78e06687621
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Research on metastasis has recently regained considerable interest with the hope that single cell technologies might reveal the most critical changes that support tumor spread. However, it is possible that part of the answer has been visible through
Externí odkaz:
https://doaj.org/article/0ec24cf4e4994ef3bb95a4c10286d88d
Autor:
Eric C. Schirmer
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/64a1a15ac3f547e2bd454b72e6673e3c
Autor:
Krishna C. Mudumbi, Rafal Czapiewski, Andrew Ruba, Samuel L. Junod, Yichen Li, Wangxi Luo, Christina Ngo, Valentina Ospina, Eric C. Schirmer, Weidong Yang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The contribution of central and peripheral channels of nuclear pores to transport of transmembrane proteins is unclear. Here the authors show that most inner nuclear membrane proteins use only peripheral channels, but some extend nuclear localization
Externí odkaz:
https://doaj.org/article/3d614e823838402aa8b9ff0997e812ae
Autor:
Charles R. Dixon, Poonam Malik, Jose I. de las Heras, Natalia Saiz-Ros, Flavia de Lima Alves, Mark Tingey, Eleanor Gaunt, A. Christine Richardson, David A. Kelly, Martin W. Goldberg, Greg J. Towers, Weidong Yang, Juri Rappsilber, Paul Digard, Eric C. Schirmer
Publikováno v:
iScience, Vol 24, Iss 9, Pp 103055- (2021)
Summary: STimulator of INterferon Genes (STING) is an adaptor for cytoplasmic DNA sensing by cGAMP/cGAS that helps trigger innate immune responses (IIRs). Although STING is mostly localized in the ER, we find a separate inner nuclear membrane pool of
Externí odkaz:
https://doaj.org/article/7c77bb3feb48478187feaae2f2cec97e
Autor:
Alex A. Makarov, Juan Zou, Douglas R. Houston, Christos Spanos, Alexandra S. Solovyova, Cristina Cardenal-Peralta, Juri Rappsilber, Eric C. Schirmer
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Lamin A is critical for nuclear architecture but its structure and assembly are not fully understood. Here, the authors use quantitative cross-linking mass spectrometry to map intra- and intermolecular interactions within lamin homomers, providing in
Externí odkaz:
https://doaj.org/article/caf6c534ab4f4275b1626a524f801501
Autor:
Jingxian Duan, Jorge Navarro-Dorado, Jill H. Clark, Nicholas P. Kinnear, Peter Meinke, Eric C. Schirmer, A. Mark Evans
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Although calcium signals are known to be critical for many cellular processes, how signaling elicits specific functions remains unclear. In visually striking work, Duan et al. reveal that networks of cytoplasmic nanocourses orchestrate cell activity
Externí odkaz:
https://doaj.org/article/1588c52787ed490bbdbdcbdbcc560603