Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eric C. Arakel"'
Autor:
Haixia Zhang, Alex Hanson, Tobias Scherf de Almeida, Christopher Emfinger, Conor McClenaghan, Theresa Harter, Zihan Yan, Paige E. Cooper, G. Schuyler Brown, Eric C. Arakel, Robert P. Mecham, Atilla Kovacs, Carmen M. Halabi, Blanche Schwappach, Maria S. Remedi, Colin G. Nichols
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunits, the most common mutations being SUR2[R1154Q] and SUR2[R1154W], carried by a
Externí odkaz:
https://doaj.org/article/49205ba65db14c0c92f39428e2cf79af
Autor:
Eric C Arakel, Blanche Schwappach
Publikováno v:
eLife, Vol 6 (2017)
Advances in imaging techniques have shed new light on the structure of vesicles formed by COPI protein complexes.
Externí odkaz:
https://doaj.org/article/5b338a84fc5a45858b87caef1b1e0fcb
Autor:
G. Schuyler Brown, Theresa M. Harter, Atilla Kovacs, Alex Hanson, Robert P. Mecham, Haixia Zhang, Paige E. Cooper, Colin G. Nichols, Blanche Schwappach, Christopher H. Emfinger, Carmen M. Halabi, Zihan Yan, Tobias Scherf de Almeida, Conor McClenaghan, Maria S. Remedi, Eric C. Arakel
Publikováno v:
JCI Insight, Vol 6, Iss 5 (2021)
JCI Insight
JCI Insight
Cantu syndrome (CS) is caused by gain-of-function (GOF) mutations in pore-forming (Kir6.1, KCNJ8) and accessory (SUR2, ABCC9) ATP-sensitive potassium (KATP) channel subunits, the most common mutations being SUR2[R1154Q] and SUR2[R1154W], carried by a
Autor:
Jonathan S. Weissman, Sarah Haßdenteufel, Maya Schuldiner, Elizabeth A. Costa, Martin Jung, Eric C. Arakel, Silvia G. Chuartzman, Calvin H. Jan, Naama Aviram, Blanche Schwappach, Tslil Ast, Johanna Dudek, Richard Zimmermann, Stefan Schorr
Publikováno v:
Nature
In eukaryotes, up to one-third of cellular proteins are targeted to the endoplasmic reticulum, where they undergo folding, processing, sorting and trafficking to subsequent endomembrane compartments(1). Targeting to the endoplasmic reticulum has been
Autor:
Alejandro F. Estrada, Martina Huranova, Blanche Schwappach, Anne Spang, Eric C. Arakel, E-Ming Rau
Publikováno v:
Journal of Cell Science.
The Arf GTPase controls formation of the COPI vesicle coat. Recent structural models of COPI revealed the positioning of two Arf1 molecules in contrasting molecular environments. Each of these pockets for Arf1 is expected to also accommodate an Arf G
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Membrane recruitment of coatomer and formation of coat protein I (COPI)-coated vesicles is crucial to homeostasis in the early secretory pathway. The conformational dynamics of COPI during cargo capture and vesicle formation is incompletely understoo
Autor:
Maya Schuldiner, Omer Goldmann, Silvia G. Chuartzman, Uri Weill, Eric C. Arakel, Sean Munro, Blanche Schwappach, Matan Golan
Publikováno v:
Traffic
Traffic (Copenhagen, Denmark)
Traffic (Copenhagen, Denmark)
A third of yeast genes encode for proteins that function in the endomembrane system. However, the precise localization for many of these proteins is still uncertain. Here, we visualized a collection of ~500 N-terminally, green fluorescent protein (GF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6dafcd7d5b67e471484ee4c67f53d7
https://hdl.handle.net/21.11116/0000-0000-D4C9-E21.11116/0000-0001-26E0-721.11116/0000-0001-26E1-621.11116/0000-0001-26DD-C21.11116/0000-0001-26DE-B21.11116/0000-0001-26DF-A
https://hdl.handle.net/21.11116/0000-0000-D4C9-E21.11116/0000-0001-26E0-721.11116/0000-0001-26E1-621.11116/0000-0001-26DD-C21.11116/0000-0001-26DE-B21.11116/0000-0001-26DF-A
Autor:
Blanche Schwappach, Eric C. Arakel
Publikováno v:
Journal of cell science. 131(7)
There was an error published in J. Cell Sci. 131 , [jcs209890][1] ([doi:10.1242/209890][2]). The Key panel of the poster and of the accompanying slides 1–5 contained an incorrect label. The correct label is: ![Figure][3] This has now been corrected
Autor:
Eric C. Arakel, Blanche Schwappach
Publikováno v:
Journal of Cell Science
The coat protein complex I (COPI) allows the precise sorting of lipids and proteins between Golgi cisternae and retrieval from the Golgi to the ER. This essential role maintains the identity of the early secretory pathway and impinges on key cellular
Autor:
Blanche Schwappach, Eric C. Arakel
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
COPI-coated vesicles mediate trafficking within the Golgi apparatus and from the Golgi to the endoplasmic reticulum. The structures of membrane protein coats, including COPI, have been extensively studied with