Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Eric C Nordby"'
Publikováno v:
Antiviral Research. 51:111-125
Analysis of a large compound library in a high throughput virus infection assay screen identified the benzothiophene PD146626 as a potent and specific inhibitor of herpes simplex virus type 1 (HSV-1) replication. PD146626 possessed an EC 50 and EC 90
Publikováno v:
Virology. 253(2):288-298
ICP0R is the polypeptide product of an alternatively spliced transcript of the gene encoding the transactivator protein ICP0 of herpes simplex virus type 1 (HSV-1). Although it has been shown to act as a transrepressor of gene expression in transfect
Publikováno v:
Virology. 228(2):218-228
ICP0R is a truncated form of the herpes simplex virus type 1 (HSV-1) transactivator protein ICP0 that is synthesized at low levels during infection through an alternative splicing mechanism. In transient expression assays, ICP0R has been shown to inh
Autor:
Takeshi Nakamura, Wataru Watanabe, Hidetsura Cho, Eric C Nordby, Peter Craig Weber, Harriet W. Hamilton, Susan Elizabeth Hagen, Stefanie L Boulware, Gisele Nishiguchi, Stephen J. Gracheck, John D Domagala, Satoru Ikeda
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 12:2981-2983
A series of novel benzthiodiazepinones was studied as antiherpetic agents. Significant improvements in potency and therapeutic index in a viral replication assay were realized over the starting molecule. The role of stereospecific substitution on the
Autor:
Matthew Bowen, Eric C. Nordby
Publikováno v:
Behavioral Sciences & the Law. 11:205-211
This study examines factors that are part of the test for whether a plaintiff may recover damages due to the negligent infliction of emotional distress to a bystander. Subjects were 96 eligible jurors from two California counties. They were presented
Autor:
Carolyn J. Bruzdzinski, Sonia M. Suter, Maureen Riordan-Johnson, Eric C. Nordby, Thomas D. Gelehrter
Publikováno v:
Journal of Biological Chemistry. 265:2078-2085
We have reported that glucocorticoids and cyclic nucleotides regulate tissue-type plasminogen activator activity in HTC rat hepatoma cells primarily by modulating plasminogen activator inhibitor (PAI-1) gene expression. To investigate the molecular m
Publikováno v:
Journal of virology. 70(11)
The immediate-early protein ICP0 (infected-cell polypeptide 0) of herpes simplex virus type 1 (HSV-1) is a promiscuous transactivator of both viral and nonviral promoters in transient expression assays. Failure to splice the second of two introns in