Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Eric C, Bolton"'
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213800 (2019)
[This corrects the article DOI: 10.1371/journal.pone.0156145.].
Externí odkaz:
https://doaj.org/article/b89831ed86734083bf4e6e2852b44296
Publikováno v:
PLoS ONE, Vol 11, Iss 5, p e0156145 (2016)
Androgen receptor (AR) signaling is crucial to the development and homeostasis of the prostate gland, and its dysregulation mediates common prostate pathologies. The mechanisms whereby AR regulates growth suppression and differentiation of luminal ep
Externí odkaz:
https://doaj.org/article/10e7d9ab4e884a0eabbbf4f249f28115
Autor:
Eung Chang Kim, Jiaren Zhang, Andy Y. Tang, Eric C. Bolton, Justin S. Rhodes, Catherine A. Christian-Hinman, Hee Jung Chung
Publikováno v:
Proceedings of the National Academy of Sciences. 118
Significance Epileptic encephalopathy (EE) is a devastating neurologic disorder characterized by early-onset seizures with severe cognitive and psychomotor impairments. EE is associated with dominant mutations in the KCNQ2 gene which encodes the K v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b84a63c25b3d3bf1e0870ba57d3a31d
https://doi.org/10.1073/pnas.2021265118
https://doi.org/10.1073/pnas.2021265118
Androgen Receptor-Mediated Growth Suppression of HPr-1AR and PC3-Lenti-AR Prostate Epithelial Cells.
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0138286 (2015)
The androgen receptor (AR) mediates the developmental, physiologic, and pathologic effects of androgens including 5α-dihydrotestosterone (DHT). However, the mechanisms whereby AR regulates growth suppression and differentiation of luminal epithelial
Externí odkaz:
https://doaj.org/article/2a82a75fb0264145bdbfbd2c1a62c197
Autor:
Congcong Chen, Mary Hong, Erik Procko, Hee Jung Chung, Eric C. Bolton, Jaimin Patel, Emad Tajkhorshid, Rebecca Choi, Shashank Pant, Eung Chang Kim, Jiaren Zhang, Dhruv Joshi, Kin Lam
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-19 (2020)
Scientific Reports
Scientific Reports
Kv7 channels are enriched at the axonal plasma membrane where their voltage-dependent potassium currents suppress neuronal excitability. Mutations in Kv7.2 and Kv7.3 subunits cause epileptic encephalopathy (EE), yet the underlying pathogenetic mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ced98e2040ffc478394027088eba394
https://doi.org/10.1038/s41598-020-61697-6
https://doi.org/10.1038/s41598-020-61697-6
Publikováno v:
The Prostate. 78:521-531
Background Androgens and the androgen receptor (AR) are necessary for the development, function, and homeostatic growth regulation of the prostate gland. However, once prostate cells are transformed, the AR is necessary for the proliferation and surv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a98b2b7822d05d7e201338416f2ff537
https://doi.org/10.1002/pros.23497
https://doi.org/10.1002/pros.23497
Publikováno v:
PLoS Genetics, Vol 3, Iss 6, p e94 (2007)
The glucocorticoid receptor (GR) associates with glucocorticoid response elements (GREs) and regulates selective gene transcription in a cell-specific manner. Native GREs are typically thought to be composite elements that recruit GR as well as other
Externí odkaz:
https://doaj.org/article/3b34add220a5445a99094c3773387adf
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213800 (2019)
PLoS ONE
PLoS ONE
Androgen receptor (AR) signaling is crucial to the development and homeostasis of the prostate gland, and its dysregulation mediates common prostate pathologies. The mechanisms whereby AR regulates growth suppression and differentiation of luminal ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc6d18d711448d641cf57fc91485865
http://europepmc.org/articles/PMC6415800?pdf=render
http://europepmc.org/articles/PMC6415800?pdf=render
Autor:
Steven K. Clinton, Joshua W. Smith, Nancy E. Moran, Matthew A. Wallig, Jennifer M. Thomas-Ahner, Eric C. Bolton, John W. Erdman, Nikki A. Ford
β-Carotene-15,15’-dioxygenase (BCO1) cleaves dietary carotenoids at the central 15,15’ double bond, most notably acting on β-carotene to yield retinal. However, Bco1 disruption also impacts diverse physiological end points independent of dietar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27469bab43d97decba6c6becbcad6b87
https://europepmc.org/articles/PMC5256971/
https://europepmc.org/articles/PMC5256971/
Publikováno v:
Journal of Biological Chemistry. 287:31195-31206
The androgen receptor (AR) mediates the effects of male sexual hormones on development and physiology. Alterations in AR function are central to reproductive disorders, prostate cancer, and Kennedy disease. AR activity is influenced by post-translati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0aea6ba4da5d11d94acbde120857ab
https://doi.org/10.1074/jbc.m112.395210
https://doi.org/10.1074/jbc.m112.395210