Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Eric C, Bielefeld"'
Publikováno v:
Frontiers in Audiology and Otology, Vol 2 (2024)
Greater understanding of the molecular intricacies of acquired and hereditary hearing loss has spurred considerable advances in inner ear gene therapy. While approaches like cochlear amplification and cochlear implantation offer varying degrees of ef
Externí odkaz:
https://doaj.org/article/4ab5bbe0d82c450b84c04eb2bbd74a12
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Over 27 million people worldwide currently receive daily antiretroviral therapy for the management of HIV/AIDS. In order to prevent the continued spread of HIV, the World Health Organization (WHO) recommends the use of highly active antiretroviral th
Externí odkaz:
https://doaj.org/article/5df9c1288142461aa26313ddf0a3e6bc
Autor:
Ryan T Harrison, Eric C Bielefeld
Publikováno v:
Noise and Health, Vol 21, Iss 98, Pp 35-40 (2019)
Introduction: There are several key differences between impulse and continuous noise: the nature of the noise itself, the cochlear and neuronal structures affected, the severity to which they damage the auditory system, and the period of time in whic
Externí odkaz:
https://doaj.org/article/de4f05f25706432099d61dca96b64097
Autor:
Eric C. Bielefeld, Megan J. Kobel
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
Noise induces a broad spectrum of pathological injuries to the cochlea, reflecting both mechanical damage to the delicate architecture of the structures of the organ of Corti and metabolic damage within the organ of Corti and lateral wall tissues. Un
Externí odkaz:
https://doaj.org/article/910616c6299344bda58c8157543a5607
Publikováno v:
International Journal of Audiology. :1-7
There is evidence of ototoxicity from antiretrovirals (ARVs), and ARV therapy in pregnant/nursing mothers can expose offspring to these compounds. The current work modelled whether exposure to ARVsThe females of seven breeding pairs of C57BL6/J mice
Autor:
Ebenezer N. Yamoah, Weijie Wang, Amir M. Mafi, Eric C. Bielefeld, Jeffrey G. Mellott, Jianxin Bao, Yingying Chen
Publikováno v:
J Assoc Res Otolaryngol
Cisplatin chemotherapy often causes permanent hearing loss, which leads to a multifaceted decrease in quality of life. Identification of early cisplatin-induced cochlear damage would greatly improve clinical diagnosis and provide potential drug targe
Autor:
Ryan T. Harrison, Eric C. Bielefeld
Publikováno v:
Noise & Health
Noise and Health, Vol 21, Iss 98, Pp 35-40 (2019)
Noise and Health, Vol 21, Iss 98, Pp 35-40 (2019)
Introduction: There are several key differences between impulse and continuous noise: the nature of the noise itself, the cochlear and neuronal structures affected, the severity to which they damage the auditory system, and the period of time in whic
Autor:
Alison Reynolds, Eric C. Bielefeld
Publikováno v:
Hearing Research. 430:108706
Publikováno v:
Noise and Health, Vol 13, Iss 53, Pp 292-298 (2011)
Both the antioxidant, N-l-acetyl cysteine (NAC), and the Src inhibitor, KX1-004, have been used to protect the cochlea from hazardous noise. In order to extend our previous work on KX1-004 with noise exposure, the current studies were undertaken with
Externí odkaz:
https://doaj.org/article/91e2d868b9bf43e2af90be503847c6d8
Publikováno v:
The Journal of the Acoustical Society of America. 146:3790-3799
One of the ongoing challenges for hearing researchers is successful protection of the ear from noise injury. For decades, the most effective methods have been based on modifying the acoustic properties of the noise, either by reducing noise output fr