Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Eric Boitier"'
Autor:
Russell D. Wolfinger, Sudheer Beedanagari, Eric Boitier, Tao Chen, Philippe Couttet, Heidrun Ellinger-Ziegelbauer, Gregory Guillemain, Claire Mariet, Peter Mouritzen, Raegan O’Lone, P. Scott Pine, Tatiana Sharapova, Jian Yan, Peter S. Yuen, Karol L. Thompson
Publikováno v:
BMC Biotechnology, Vol 18, Iss 1, Pp 1-9 (2018)
Abstract Background Circulating microRNAs are undergoing exploratory use as safety biomarkers in drug development. Reverse transcription quantitative polymerase chain reaction (RT-qPCR) is one common approach used to quantitate levels of microRNAs in
Externí odkaz:
https://doaj.org/article/c2c793e7d8a5491ead046c944c014fad
Autor:
Yaligara Veeranagouda, Pierrick Rival, Catherine Prades, Claire Mariet, Jean-François Léonard, Jean-Charles Gautier, Xiaobing Zhou, Jufeng Wang, Bo Li, Marie-Laure Ozoux, Eric Boitier
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164317 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0142708.].
Externí odkaz:
https://doaj.org/article/f21dd8bff8a141c5b9b8969297336955
Autor:
Yaligara Veeranagouda, Pierrick Rival, Catherine Prades, Claire Mariet, Jean-François Léonard, Jean-Charles Gautier, Xiaobing Zhou, Jufeng Wang, Bo Li, Marie-Laure Ozoux, Eric Boitier
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142708 (2015)
MicroRNAs (miRNAs) present in tissues and biofluids are emerging as sensitive and specific safety biomarkers. MiRNAs have not been thoroughly described in M. fascicularis, an animal model used in pharmaceutical industry especially in drug safety eval
Externí odkaz:
https://doaj.org/article/6d8ee9cafc024ff4aae942dcceda00f3
Autor:
Anas Gazzah, Joon Sang Lee, Emma Wang, Nils Ternès, Hong Wang, Eric Boitier, Aude Lartigau, Mustapha Chadjaa, Colette Dib, Gaëlle Muzard, Sandrine Valence, Anne Remaury, Cintia C. Palu, Anne-Laure Bauchet
Publikováno v:
Cancer Research. 83:CT213-CT213
Background Tusamitamab ravtansine is an antibody-drug conjugate of a humanized carcinoembryonic antigen (CEA)-related cell adhesion molecule 5 (CEACAM5)-specific monoclonal antibody linked to DM4. A Phase 1/2 study (NCT02187848) showed tusamitamab ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e3629a7b9eb9c17b2026a8286ced114
https://doi.org/10.1158/1538-7445.am2023-ct213
https://doi.org/10.1158/1538-7445.am2023-ct213
Autor:
James W. Dear, Eric Boitier, Salvatore Pernagallo, David C. Duffy, Sébastien Laurent, Emma E. Morrison, Richard J. Mellanby, Lucile Sautier, Juan J. Díaz-Mochón, Aude Lartigau, David M. Rissin, John D. Tranter, Hugh Ilyine, Jean-François Léonard, Pedro Carmona-Sáez, Barbara López-Longarela, Lianne Chahman-Vos, Jordi Martorell-Marugán, Jean-Charles Gautier
Publikováno v:
López-longarela, B, Morrison, E E, Tranter, J D, Chahman-vos, L, Léonard, J, Gautier, J, Laurent, S, Lartigau, A, Boitier, E, Sautier, L, Carmona-saez, P, Martorell-marugan, J, Mellanby, R J, Pernagallo, S, Ilyine, H, Rissin, D M, Duffy, D C, Dear, J W & Díaz-mochón, J J 2020, ' Direct Detection of miR-122 in Hepatotoxicity Using Dynamic Chemical Labeling Overcomes Stability and isomiR Challenges ', Analytical Chemistry . https://doi.org/10.1021/acs.analchem.9b05449
Circulating microRNAs are biomarkers reported to be stable and translational across species. MicroRNA-122 (miR-122) is a hepatocyte-specific microRNA biomarker for drug-induced liver injury (DILI). We developed a single molecule, dynamic chemical lab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::355ebb0b8c10eadda0ff4309e718d045
https://hdl.handle.net/20.500.11820/6a3d708a-fc7c-4d13-939a-e1fedda53e81
https://hdl.handle.net/20.500.11820/6a3d708a-fc7c-4d13-939a-e1fedda53e81
Autor:
Emma Wang, Alice Gosselin, Alexei Protopopov, Colette Dib, Joon Sang Lee, Maysoun Shomali, Vasiliki Pelekanou, Nils Ternes, Christopher Soria, Patrick Cohen, Marina Celanovic, Monsif Bouaboula, Wilson Dos-Santos-Bele, Jack Pollard, Eric Boitier
Publikováno v:
Cancer Research. 81:406-406
Hormone or endocrine therapy is the primary treatment for estrogen receptor-positive (ER+) breast cancer. Selective Estrogen Receptor Modulators (SERMs) have been used for women with ER+ invasive cancer in the adjuvant setting. However, they do not f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebd616a465c44d55395fb03fb8f9b8eb
https://doi.org/10.1158/1538-7445.am2021-406
https://doi.org/10.1158/1538-7445.am2021-406
Autor:
Lianne Chahman-Vos, Jordi Martorell-Marugán, David C. Duffy, James W. Dear, Jean-Charles Gautier, Richard J. Mellanby, Sébastien Laurent, Aude Lartigau, Salvatore Pernagallo, Jean-François Léonard, John D. Tranter, Juan J. Díaz-Mochón, David M. Rissin, Barbara López-Longarela, Pedro Carmona-Sáez, Eric Boitier, Hugh Ilyine, Lucile Sautier, Emma E. Morrison
Circulating microRNAs are biomarkers reported to be stable and translational across species. miR-122 (miR-122-5p) is a hepatocyte-specific microRNA biomarker for drug-induced liver injury (DILI). Our objective was to develop an extraction-free and am
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f205f68110cb2b64aeda41e9e571e82b
https://doi.org/10.1101/777458
https://doi.org/10.1101/777458
Autor:
Xiaobing Zhou, Isabelle Guizon, Bo Li, Yaligara Veeranagouda, Tianyi Zhang, Mohamed Slaoui, Philippe Detilleux, Zhe Qu, Jufeng Wang, Yang Yang, Thierry Gury, Oliver Poetz, Jean-Charles Gautier, Bart H.J. van den Berg, Xavier Palazzi, Thomas O. Joos, Jean-François Léonard, Aziz Filali-Ansary, Eric Boitier
Publikováno v:
Toxicology and Applied Pharmacology. 303:1-10
Most studies to evaluate kidney safety biomarkers have been performed in rats. This study was conducted in Cynomolgus monkeys in order to evaluate the potential usefulness of novel biomarkers of nephrotoxicity in this species. Groups of 3 males were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3139e50ff5d0659eefc47ab57bd61e29
https://doi.org/10.1016/j.taap.2016.04.012
https://doi.org/10.1016/j.taap.2016.04.012
Autor:
Peter Mouritzen, Tatiana Sharapova, Gregory Guillemain, Heidrun Ellinger-Ziegelbauer, Karol L. Thompson, Sudheer Beedanagari, Russell D. Wolfinger, Eric Boitier, Tao Chen, Raegan O’Lone, Philippe Couttet, Claire Mariet, Peter S.T. Yuen, P. Scott Pine, Jian Yan
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 18, Iss 1, Pp 1-9 (2018)
BMC Biotechnology, Vol 18, Iss 1, Pp 1-9 (2018)
Background Circulating microRNAs are undergoing exploratory use as safety biomarkers in drug development. Reverse transcription quantitative polymerase chain reaction (RT-qPCR) is one common approach used to quantitate levels of microRNAs in samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::305c23fff690035888b60acd933373db
http://europepmc.org/articles/PMC5796571
http://europepmc.org/articles/PMC5796571
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1641
Advanced sequencing technologies like next-generation sequencing (NGS) not only detect microRNAs (miRNAs) in biological samples but also facilitate de novo identification of miRNAs. Using an Ion Torrent's Ion Proton System, here we described miRNAs s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fb19ef972bfe1bb30bf9c39999bc4e5d
https://pubmed.ncbi.nlm.nih.gov/28748475
https://pubmed.ncbi.nlm.nih.gov/28748475