Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eric Batsche"'
Autor:
Yao Xiang, Jorge Mata-Garrido, Yuanji Fu, Christophe Desterke, Eric Batsché, Ahmed Hamaï, Christine Sedlik, Youssouf Sereme, David Skurnik, Abdelali Jalil, Rachel Onifarasoaniaina, Eric Frapy, Jean-Christophe Beche, Razack Alao, Eliane Piaggio, Laurence Arbibe, Yunhua Chang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 6, Pp 1404-1426 (2024)
Abstract As an important immune stimulator and modulator, IFNγ is crucial for gut homeostasis and its dysregulation links to diverse colon pathologies, such as colitis and colorectal cancer (CRC). Here, we demonstrated that the epigenetic regulator,
Externí odkaz:
https://doaj.org/article/de2e44b1297c4b6381469b61856d34e2
Autor:
Yao Xiang, Jorge Mata-Garrido, Yuanji Fu, Christophe Desterke, Eric Batsché, Ahmed Hamaï, Christine Sedlik, Youssouf Sereme, David Skurnik, Abdelali Jalil, Rachel Onifarasoaniaina, Eric Frapy, Jean-Christophe Beche, Razack Alao, Eliane Piaggio, Laurence Arbibe, Yunhua Chang
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 10, Pp 2652-2652 (2024)
Externí odkaz:
https://doaj.org/article/da953299fd5d437394c61cb32a1d1341
Autor:
Jorge Mata-Garrido, Yao Xiang, Yunhua Chang-Marchand, Caroline Reisacher, Elisabeth Ageron, Ida Chiara Guerrera, Iñigo Casafont, Aurelia Bruneau, Claire Cherbuy, Xavier Treton, Anne Dumay, Eric Ogier-Denis, Eric Batsché, Mickael Costallat, Gwladys Revêchon, Maria Eriksson, Christian Muchardt, Laurence Arbibe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
This study reports reduced expression of the chromatin and splicing regulator HP1γ in inflammatory bowel disease (IBD) and shows that HP1γ protects against pervasive RNA splicing leading to toxic mRNA products detected in IBD, like progerin.
Externí odkaz:
https://doaj.org/article/cd62808a02c4443c8de8c01333a7ee93
Autor:
Benoit Raymond, Eric Batsche, Florence Boutillon, Yong-Zheng Wu, Dominique Leduc, Viviane Balloy, Eloïse Raoust, Christian Muchardt, Pierre L Goossens, Lhousseine Touqui
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000359 (2009)
Lethal toxin (LT) is a critical virulence factor of Bacillus anthracis, the etiological agent of anthrax, whose pulmonary form is fatal in the absence of treatment. Inflammatory response is a key process of host defense against invading pathogens. We
Externí odkaz:
https://doaj.org/article/d5a8d790f4c144628b130ca0315701a1
Autor:
Jorge Mata-Garrido, Yao Xiang, Yunhua Chang-Marchand, Caroline Reisacher, Elisabeth Ageron-ardila, Chiara Guerrera, Inigo Casafont, Aurelia Bruneau, Claire Cherbuy, Xavier Treton, Anne Dumay, Eric Ogier-Denis, Eric Batsche, Mickael Costallat, Gwladys Revêchon, Maria Eriksson, Christian Muchardt, Laurence Arbibe
Defects in RNA splicing have been linked to numerous human disorders, but remain poorly explored in inflammatory bowel disease (IBD). Here, we report that, in the gut epithelium of patients with ulcerative colitis (UC), the expression of the chromati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9df7096e159c2f7ae32a6518fcbe70dd
https://doi.org/10.1101/2020.12.30.424798
https://doi.org/10.1101/2020.12.30.424798
Autor:
Jessica Morel, Laura Sedano, Nathalie Lejal, Bruno Da Costa, Eric Batsché, Christian Muchardt, Bernard Delmas
Publikováno v:
Viruses, Vol 14, Iss 3, p 518 (2022)
Influenza virus transcription is catalyzed by the viral RNA-polymerase (FluPol) through a cap-snatching activity. The snatching of the cap of cellular mRNA by FluPol is preceded by its binding to the flexible C-terminal domain (CTD) of the RPB1 subun
Externí odkaz:
https://doaj.org/article/de39a1df99b148c1a6f46eff01f67a2d
Autor:
Priyanka Sharma, Saliha Azebi, Patrick England, Tove Christensen, Anné Møller-Larsen, Thor Petersen, Eric Batsché, Christian Muchardt
Publikováno v:
PLoS Genetics, Vol 8, Iss 9, p e1002934 (2012)
Multiple Sclerosis (MS) is an autoimmune disease associated with abnormal expression of a subset of cytokines, resulting in inappropriate T-lymphocyte activation and uncontrolled immune response. A key issue in the field is the need to understand why
Externí odkaz:
https://doaj.org/article/9dfb6888717e4c0e9d5901bd7e313522
Autor:
Marc Lavigne, Ragnhild Eskeland, Saliha Azebi, Violaine Saint-André, Suk Min Jang, Eric Batsché, Hua-Ying Fan, Robert E Kingston, Axel Imhof, Christian Muchardt
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000769 (2009)
The heterochromatin-enriched HP1 proteins play a critical role in regulation of transcription. These proteins contain two related domains known as the chromo- and the chromoshadow-domain. The chromo-domain binds histone H3 tails methylated on lysine
Externí odkaz:
https://doaj.org/article/7b7d538d14c34f8483cc97b765d7c9dd