Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Eric Batchelor"'
Publikováno v:
npj Systems Biology and Applications, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract Energy landscapes can provide intuitive depictions of population heterogeneity and dynamics. However, it is unclear whether individual cell behavior, hypothesized to be determined by initial position and noise, is faithfully recapitulated. U
Externí odkaz:
https://doaj.org/article/dbd72642ec304b8a925f90879db4a4ef
Autor:
Ryan L Hanson, Eric Batchelor
Publikováno v:
Molecular Systems Biology, Vol 18, Iss 12, Pp n/a-n/a (2022)
Abstract In response to different cellular stresses, the transcription factor p53 undergoes different dynamics. p53 dynamics, in turn, control cell fate. However, distinct stresses can generate the same p53 dynamics but different cell fate outcomes,
Externí odkaz:
https://doaj.org/article/ef79de4db317446fbe0ab9c2a3828c8e
Autor:
Zuqin Nie, Chunhua Guo, Subhendu K Das, Carson C Chow, Eric Batchelor, S Stoney Simons Jnr, David Levens
Publikováno v:
eLife, Vol 9 (2020)
Supraphysiological MYC levels are oncogenic. Originally considered a typical transcription factor recruited to E-boxes (CACGTG), another theory posits MYC a global amplifier increasing output at all active promoters. Both models rest on large-scale g
Externí odkaz:
https://doaj.org/article/0acc578d75da4e5c892d7a40c0cd7806
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 9, Pp n/a-n/a (2019)
Abstract The p53 tumor suppressor regulates distinct responses to cellular stresses. Although different stresses generate different p53 dynamics, the mechanisms by which cells decode p53 dynamics to differentially regulate target genes are not well u
Externí odkaz:
https://doaj.org/article/42afd759df5142d1a68142e38efee817
Autor:
Amie D Moody, Eric Batchelor
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
Externí odkaz:
https://doaj.org/article/533c33e9ddae4fb29ac6ee0392041dd3
Publikováno v:
bioRxiv
SummaryEnergy landscapes can provide intuitive depictions of population heterogeneity and dynamics. However, it is unclear whether individual cell behavior, hypothesized to be determined by initial position and noise, is faithfully recapitulated. Usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31bc6a303fe4cf0f50612fd1b52b3cc7
https://doi.org/10.1101/2023.05.22.541793
https://doi.org/10.1101/2023.05.22.541793
Autor:
Alexie A. Larson, Ahmed S. Shams, Shawna L. McMillin, Brian P. Sullivan, Cha Vue, Zachery A. Roloff, Eric Batchelor, Michael Kyba, Dawn A. Lowe
Publikováno v:
American Journal of Physiology-Cell Physiology. 322:C1123-C1137
The size of the satellite cell pool is reduced in estradiol (E2)-deficient female mice and humans. Here, we use a combination of in vivo and in vitro approaches to identify mechanisms, whereby E2 deficiency impairs satellite cell maintenance. By meas
Autor:
Christina M. Annunziata, Margaret C. Cam, Fathi Elloumi, Eric Batchelor, Michael J. Kruhlak, Marianne Kim, Jana M. James, Michelle Ozaki, Lidia Hernandez, Elizabeth Jordan, Carrie D. House
Understanding the mechanisms supporting tumor-initiating cells (TIC) is vital to combat advanced-stage recurrent cancers. Here, we show that in advanced ovarian cancers NFκB signaling via the RelB transcription factor supports TIC populations by dir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092f985fec1897f9e3833b64f8e6235d
https://doi.org/10.1158/0008-5472.c.6509204.v1
https://doi.org/10.1158/0008-5472.c.6509204.v1
Autor:
Christina M. Annunziata, Margaret C. Cam, Fathi Elloumi, Eric Batchelor, Michael J. Kruhlak, Marianne Kim, Jana M. James, Michelle Ozaki, Lidia Hernandez, Elizabeth Jordan, Carrie D. House
RELA Chromatin immunoprecipitation, PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab1c53187f8350b5c29befd0098579b
https://doi.org/10.1158/0008-5472.22415225.v1
https://doi.org/10.1158/0008-5472.22415225.v1
Autor:
Christina M. Annunziata, Margaret C. Cam, Fathi Elloumi, Eric Batchelor, Michael J. Kruhlak, Marianne Kim, Jana M. James, Michelle Ozaki, Lidia Hernandez, Elizabeth Jordan, Carrie D. House
primer sequences for qPCR of NF-kB regulated genes, and for chromatin immunoprecipitation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee70337efcb51e2c863d9fdb7e2afcf
https://doi.org/10.1158/0008-5472.22415222.v1
https://doi.org/10.1158/0008-5472.22415222.v1