Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eric B. Wright"'
Autor:
Eric B. Wright, Deborah A. Lannigan
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The Serine/Threonine protein kinase family, p90 ribosomal S6 kinases (RSK) are downstream effectors of extracellular signal regulated kinase 1/2 (ERK1/2) and are activated in response to tyrosine kinase receptor or G-protein coupled receptor signalin
Externí odkaz:
https://doaj.org/article/5df5a120d9e7430099497b664583409b
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1798-1809 (2021)
Identifying isoform-specific inhibitors for closely related kinase family members remains a substantial challenge. The necessity for achieving this specificity is exemplified by the RSK family, downstream effectors of ERK1/2, which have divergent phy
Externí odkaz:
https://doaj.org/article/24e72094666b4d03bb12ea13e0ecdbd6
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100270- (2021)
Summary: A FACS protocol is described that eliminates isolation and staining artifacts to allow accurate comparison between cell populations isolated from organs obtained from disparate mouse groups. This protocol was validated by characterizing the
Externí odkaz:
https://doaj.org/article/312d549c52364b15862dbe7d55cdb96f
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 36, Iss 1, Pp 1798-1809 (2021)
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Journal of Enzyme Inhibition and Medicinal Chemistry
article-version (VoR) Version of Record
Identifying isoform-specific inhibitors for closely related kinase family members remains a substantial challenge. The necessity for achieving this specificity is exemplified by the RSK family, downstream effectors of ERK1/2, which have divergent phy
Autor:
Ariel T Tarr, Peyton R Sayasith, Lin Lin, Deborah A. Lannigan, Yu Li, George A. O'Doherty, Sugyeom Kim, Eric B Wright, Sharia Yasmin
Publikováno v:
J Org Chem
The synthesis of two series of five kaempfer-3-ols was described. The first set all have a C-3 hydroxyl group and the second has a carboxymethoxy ether at the C-3 position. Both series have variable substitution at the C-4′ position (i.e., OH, Cl,
Publikováno v:
STAR Protocols, Vol 2, Iss 1, Pp 100270-(2021)
STAR Protocols
STAR Protocols
Summary A FACS protocol is described that eliminates isolation and staining artifacts to allow accurate comparison between cell populations isolated from organs obtained from disparate mouse groups. This protocol was validated by characterizing the e
Publikováno v:
Chem Commun (Camb)
Five cyclitol analogues of SL0101 with variable substitution at the C-4' position (i.e., OH, Cl, F, H, OMe) were synthesized. The series of analogues were evaluated for their ability to inhibit p90 ribosomal S6 kinase (RSK) activity. The study demons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d85ab619ee1085589b5c1586d1d6a057
https://europepmc.org/articles/PMC7285658/
https://europepmc.org/articles/PMC7285658/
Publikováno v:
The Astrophysical Journal. 500:342-354
The evolution of a supernova remnant through the transition from an adiabatic Sedov-Taylor blast wave to a radiative pressure-driven snowplow phase is studied using one- and two-dimensional hydrodynamic simulations. This transition is marked by a cat