Výsledky vyhledávání - "Eric B. Patterson"

The Role of Mitogen-Activated Protein Kinases in Asthma

Autor: Manzoor M. Khan, Eric B. Patterson

Publikováno v: Current Immunology Reviews. 11:132-146

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3fe834dd789298f4a92aa78ef69a3118
https://doi.org/10.2174/1573395511666150615225641

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Molecular cloning of a cDNA of a camptothecin-resistant human DNA topoisomerase I and identification of mutation sites

Autor: Hiroomi Tamura, Jack D. Keene, Ken Nishikawa, Toshiwo Andoh, Tomotake Ikeda, Eric B. Patterson, Chie Kohchi, Kosuke Okada, Eigil Kjeldsen, Osamu Koiwai, Ryutaro Yamada

Publikováno v: Nucleic Acids Research. 19:69-75

Camptothecin (CPT), a plant alkaloid with antitumor activity, is a specific inhibitor of eukaryotic DNA topoisomerase I. We have previously isolated and characterized a CPT-resistant topoisomerase I isolated from a CPT-resistant human leukemia cell l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f99a68fe3b68634542c2239da73bf680
https://doi.org/10.1093/nar/19.1.69

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Histamine affects STAT6 phosphorylation via its effects on IL-4 secretion: role of H1 receptors in the regulation of IL-4 production

Autor: Geetanjali Kharmate, Zhongfeng Liu, Eric B. Patterson, Manzoor M. Khan

Signal Transducer and Activator of Transcription (STAT)-6 is a transcriptional factor activated mainly through the cytokines IL-4 and IL-13 leading to the Th2 cell differentiation. Th2 cells play a role in the etiology and pathogenesis of allergic di

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01acd391a2359007e302f21f9b47657
https://europepmc.org/articles/PMC1913482/

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Involvement of histamine H1 and H2 receptors in the regulation of STAT-1 phosphorylation: inverse agonism exhibited by the receptor antagonists

Autor: Shilpa P. Sakhalkar, Eric B. Patterson, Manzoor M. Khan

Publikováno v: International immunopharmacology. 5(7-8)

Signal transducer and activator of transcription-1 (STAT1) is a latent signal transducer protein which, on phosphorylation, is translocated from the cytoplasm to the nucleus and is subsequently activated. This study was designed to determine the invo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db17bb3b5b81f397a15adc5aded47058
https://pubmed.ncbi.nlm.nih.gov/15914334

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Adenovirus Inversely Modulates Target Cell Class I Antigen Expression and Sensitivity to Natural Killing

Autor: Jeffrey R. Dawson, Walter J. Storkus, Peter Cresswell, Eric B. Patterson

Publikováno v: Immunobiology of HLA ISBN: 9783662389805

Natural killer (NK) cell-mediated cytolysis occurs without apparent major histocompatibility complex (MHC) restriction (1). However, recent evidence suggests that the level of MHC class I antigens expressed by the target cell may influence its sensit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::149529fd6bb007bfd72d0651e59c0cf0
https://doi.org/10.1007/978-3-662-39946-0_40

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