Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Eric B Wong"'
Publikováno v:
PLoS Pathogens, Vol 15, Iss 12, p e1008239 (2019)
Cells sensing infection produce Type I interferons (IFN-I) to stimulate Interferon Stimulated Genes (ISGs) that confer resistance to viruses. During lympho-hematogenous spread of the mouse pathogen ectromelia virus (ECTV), the adaptor STING and the t
Externí odkaz:
https://doaj.org/article/f0165bc53eed4c3385cb2e11b2e88c34
Autor:
Astrid Wintering, Anna Hecht, Julia Meyer, Eric B. Wong, Juwita Hübner, Sydney Abelson, Kira Feldman, Vanessa E. Kennedy, Cheryl A.C. Peretz, Deborah L. French, Jean Ann Maguire, Chintan Jobaliya, Marta Rojas Vasquez, Sunil Desai, Robin Dulman, Eneida Nemecek, Hilary Haines, Mahmoud Hammad, Alaa El Haddad, Scott C. Kogan, Zied Abdullaev, Farid F. Chehab, Sarah K. Tasian, Catherine C. Smith, Mignon L. Loh, Elliot Stieglitz
Publikováno v:
Haematologica, Vol 999, Iss 1 (2023)
Mutations in five canonical Ras pathway genes (NF1, NRAS, KRAS, PTPN11 and CBL) are detected in nearly 90% of patients with juvenile myelomonocytic leukemia (JMML), a frequently fatal malignant neoplasm of early childhood. In this report, we describe
Externí odkaz:
https://doaj.org/article/6b7a3df1a4054f309e85875af70a1441
Autor:
Lingjuan Tang, Cory J. Knudson, Eric B. Wong, Colby Stotesbury, Luis J. Sigal, Pedro Alves-Peixoto, Maria Ferez, Avital Lev
Publikováno v:
The Journal of Experimental Medicine
Ferez et al. show that during a viral infection, the levels of Qa-1b expression are decreased in infected cells and increased in some bystander immune cells to respectively promote or inhibit their killing by activated NK cells.
Natural killer (
Natural killer (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ee85e60b3261c074c760ad17867a05
https://doi.org/10.1084/jem.20201782
https://doi.org/10.1084/jem.20201782
Autor:
Avital Lev, Colby Stotesbury, Luis J. Sigal, Daniel Rubio, Ren-Huan Xu, Eric B. Wong, Min Fang
Publikováno v:
Cell Reports, Vol 24, Iss 1, Pp 142-154 (2018)
Summary: Circulating natural killer (NK) cells help protect the host from lympho-hematogenous acute viral diseases by rapidly entering draining lymph nodes (dLNs) to curb virus dissemination. Here, we identify a highly choreographed mechanism underly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42e3687606764418cfcd711b7c6d6f9c
http://www.sciencedirect.com/science/article/pii/S2211124718308994
http://www.sciencedirect.com/science/article/pii/S2211124718308994
Autor:
Eric B. Wong, Carolina R. Melo-Silva, Cory J. Knudson, Maria Ferez, Margarida Correia-Neves, Pedro Alves-Peixoto, Luis J. Sigal, Colby Stotesbury
Publikováno v:
J Virol
It is well established that chronic viral infections can cause immune suppression, resulting in increased susceptibility to other infectious diseases. However, the effects of chronic viral infection on T-cell responses and vaccination against highly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c79b84ac169ca82d563d8059f5211b5
https://pubmed.ncbi.nlm.nih.gov/31826990
https://pubmed.ncbi.nlm.nih.gov/31826990
Autor:
Carolina R. Melo-Silva, Eric B. Wong, Pedro Alves-Peixoto, Luis J. Sigal, Cory J. Knudson, Colby Stotesbury, Margarida Correia-Neves, Maria Ferez
Publikováno v:
J Virol
Chronic viral infections. like those of humans with cytomegalovirus, human immunodeficiency virus (even when under antiretroviral therapy), and hepatitis C virus or those of mice with lymphocytic choriomeningitis virus (LCMV) clone 13 (CL13), result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c5ab26e53e6ab01bd579e98fa2e4cd2
https://pubmed.ncbi.nlm.nih.gov/31776282
https://pubmed.ncbi.nlm.nih.gov/31776282
Autor:
Luis J. Sigal, Eric B. Wong, Brian Montoya, Colby Stotesbury, Nicole A. Wilski, Christina Del Casale, Christopher M. Snyder
Publikováno v:
J Immunol
CMV has been proposed to play a role in cancer progression and invasiveness. However, CMV has been increasingly studied as a cancer vaccine vector, and multiple groups, including ours, have reported that the virus can drive antitumor immunity in cert
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f64e5cbe82662237bc291b18c7e7972
https://pubmed.ncbi.nlm.nih.gov/32284333
https://pubmed.ncbi.nlm.nih.gov/32284333
Autor:
Timothy K. Cooper, Daisuke Kitamura, Melinda J. Elias, Chetna Soni, Zia Ur Rahman, Sathi Babu Chodisetti, Stephanie L. Schell, Eric B. Wong, Phillip P. Domeier
Publikováno v:
The Journal of Experimental Medicine
B cell–intrinsic IFN-γ receptor signaling through STAT1 is required for the generation of spontaneous germinal centers, which can lead to pathogenic autoantibody production.
Spontaneously developed germinal centers (GCs [Spt-GCs]) harbor auto
Spontaneously developed germinal centers (GCs [Spt-GCs]) harbor auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::407af161a2eb6588c645942489bef712
http://europepmc.org/articles/PMC4854731
http://europepmc.org/articles/PMC4854731
Autor:
Eric B. Wong, Cyrus Modavi, Shakked O. Halperin, David V. Schaffer, Connor J. Tou, John E. Dueber
Publikováno v:
Nature. 560(7717)
The capacity to diversify genetic codes advances our ability to understand and engineer biological systems1,2. A method for continuously diversifying user-defined regions of a genome would enable forward genetic approaches in systems that are not ame
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd1d7af1b1616a3937c13479ae013949
https://pubmed.ncbi.nlm.nih.gov/30388408
https://pubmed.ncbi.nlm.nih.gov/30388408
Autor:
Eric B. Wong, Shwetank, Phillip P. Domeier, Stephanie L. Schell, Zia Ur Rahman, Melinda J. Elias, Chetna Soni, Aron E. Lukacher, Timothy K. Cooper, Tahsin N. Khan
Publikováno v:
Journal of Autoimmunity. 63:31-46
The inhibitory IgG Fc receptor (FcγRIIB) deficiency and 129 strain-derived signaling lymphocyte activation molecules (129-SLAMs) are proposed to contribute to the lupus phenotype in FcγRIIB-deficient mice generated using 129 ES cells and backcrosse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032e1d906c67a7b20ff929f5b779e903
https://doi.org/10.1016/j.jaut.2015.06.011
https://doi.org/10.1016/j.jaut.2015.06.011