Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Eric B, Gonzales"'
Autor:
Zhicheng Zuo, Rachel N. Smith, Zhenglan Chen, Amruta S. Agharkar, Heather D. Snell, Renqi Huang, Jin Liu, Eric B. Gonzales
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Acid-sensing ion channels (ASICs) sense changes in extracellular acidity with Ca2+ as an allosteric modulator and channel blocker. Here authors use electrophysiology and molecular dynamics simulation to identify the residue in ASIC3 which modulates p
Externí odkaz:
https://doaj.org/article/13f55aaea8244e21bacd420c63712ecc
Autor:
Amruta S. Agharkar, Eric B. Gonzales
Publikováno v:
Journal of Pharmacological Sciences, Vol 133, Iss 3, Pp 184-186 (2017)
Acid-sensing ion channels (ASICs) are proton-sensitive sodium channels that open in response to lowered extracellular pH and are expressed in the central and peripheral nervous systems. The ASIC3 subtype is found primarily in the periphery where the
Externí odkaz:
https://doaj.org/article/d938522cdafa427baa2ee6990c7ef6d0
Publikováno v:
F1000Research, Vol 3 (2014)
Creatine is an endogenous compound synthesized from arginine, glycine and methionine. This dietary supplement can be acquired from food sources such as meat and fish, along with athlete supplement powders. Since the majority of creatine is stored in
Externí odkaz:
https://doaj.org/article/44680a7696444a80a362e5941a55f129
Autor:
Eric B. Gonzales, Abdeslam Chagraoui, Jean-Claude do Rego, Zhenglan Chen, Hugo R. Arias, Jean Luc Do Rego, Petra Scholze, Youssef Anouar, Ren-Qi Huang
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2020, 101, pp.109930-. ⟨10.1016/j.pnpbp.2020.109930⟩
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020, 101, pp.109930-. ⟨10.1016/j.pnpbp.2020.109930⟩
Progress in Neuro-Psychopharmacology and Biological Psychiatry, Elsevier, 2020, 101, pp.109930-. ⟨10.1016/j.pnpbp.2020.109930⟩
Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2020, 101, pp.109930-. ⟨10.1016/j.pnpbp.2020.109930⟩
To determine whether (+)-catharanthine induces sedative- or anxiolytic/anxiogenic-like activity in male mice, proper animal paradigms were used. The results showed that (+)-catharanthine induces sedative-like activity in the 63–72 mg/Kg dose range
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f072900d98100766457d7ace03d54c4
https://hal.archives-ouvertes.fr/hal-03489760
https://hal.archives-ouvertes.fr/hal-03489760
Publikováno v:
Medical educationREFERENCES. 54(5)
Autor:
Hugo R, Arias, Jean Luc, Do Rego, Jean Claude, Do Rego, Zhenglan, Chen, Youssef, Anouar, Petra, Scholze, Eric B, Gonzales, Renqi, Huang, Abdeslam, Chagraoui
Publikováno v:
Progress in neuro-psychopharmacologybiological psychiatry. 101
To determine whether (+)-catharanthine induces sedative- or anxiolytic/anxiogenic-like activity in male mice, proper animal paradigms were used. The results showed that (+)-catharanthine induces sedative-like activity in the 63-72 mg/Kg dose range in
Autor:
Heather D. Snell, Amruta S. Agharkar, Jin Liu, Rachel N. Smith, Eric B. Gonzales, Ren-Qi Huang, Zhicheng Zuo, Zhenglan Chen
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Acid-sensing ion channels (ASICs) evolved to sense changes in extracellular acidity with the divalent cation calcium (Ca2+) as an allosteric modulator and channel blocker. The channel-blocking activity is most apparent in ASIC3, as removing Ca2+ resu
Publikováno v:
Pharmacological Reports. 70:316-321
Background The objective of this study was to evaluate creatine as an anti-nociceptive compound in an animal model of thermal and inflammatory pain. Creatine has the structural potential to interact with acid-sensing ion channels (ASIC), which have b
Publikováno v:
Neurotherapeutics
Acid-sensing ion channels (ASICs) are a family of ion channels, consisting of four members; ASIC1 to 4. These channels are sensitive to changes in pH and are expressed throughout the central and peripheral nervous systems—including brain, spinal co
Autor:
Nathalie Sumien, Eric B. Gonzales
Publikováno v:
Journal of Alzheimer's Disease. 57:1137-1144
Alzheimer's disease prevalence has reached epidemic proportion with very few treatment options, which are associated with a multitude of side effects. A potential avenue of research for new therapies are protons, and their associated receptor: acid-s