Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Eric B, Dammer"'
Autor:
Kaylin M. Carey, Corey D. Young, Alexis J. Clark, Eric B. Dammer, Rajesh Singh, James W. Lillard
Publikováno v:
Journal of Ovarian Research, Vol 17, Iss 1, Pp 1-18 (2024)
Abstract High-grade serous ovarian cancer (HGSOC) is marked by significant molecular diversity, presenting a major clinical challenge due to its aggressive nature and poor prognosis. This study aims to deepen the understanding of HGSOC by characteriz
Externí odkaz:
https://doaj.org/article/481b6655b9ed4a5fb5eafbc237cd95de
Autor:
Qi Guo, Lingyan Ping, Eric B. Dammer, Duc M. Duong, Luming Yin, Kaiming Xu, Anantharaman Shantaraman, Edward J. Fox, Todd E Golde, Erik C.B. Johnson, Blaine R. Roberts, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-30 (2024)
Abstract Introduction Heparin binding proteins (HBPs) with roles in extracellular matrix assembly are strongly correlated to β-amyloid (Aβ) and tau pathology in Alzheimer’s disease (AD) brain and cerebrospinal fluid (CSF). However, it remains cha
Externí odkaz:
https://doaj.org/article/45c6f5f8193444e2b5dcf0ca69a39efd
Autor:
Ashlyn G. Johnson, Eric B. Dammer, James A. Webster, Duc M. Duong, Nicholas T. Seyfried, Chadwick M. Hales
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 8, Pp 2138-2152 (2024)
Abstract Objective To define tauopathy‐associated changes in the human gray and white matter proteome. Method We applied tandem mass tagged labeling and mass spectrometry, consensus, and ratio weighted gene correlation network analysis (WGCNA) to g
Externí odkaz:
https://doaj.org/article/32123b1f3a544e85ae4e477d7259f48a
Autor:
Anantharaman Shantaraman, Eric B. Dammer, Obiadada Ugochukwu, Duc M. Duong, Luming Yin, E. Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B. Lee, John Q. Trojanowski, David A. Bennett, James J. Lah, Allan I. Levey, Nicholas T. Seyfried, Lenora Higginbotham
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-24 (2024)
Abstract Lewy body dementia (LBD), a class of disorders comprising Parkinson’s disease dementia (PDD) and dementia with Lewy bodies (DLB), features substantial clinical and pathological overlap with Alzheimer’s disease (AD). The identification of
Externí odkaz:
https://doaj.org/article/7ae7acdfdb7b4c38ba5851ba50f50b73
Autor:
Alyssa F. Pybus, Sara Bitarafan, Rowan O. Brothers, Alivia Rohrer, Arushi Khaitan, Felix Rivera Moctezuma, Kareena Udeshi, Brae Davies, Sydney Triplett, Martin N. Griffin, Eric B. Dammer, Srikant Rangaraju, Erin M. Buckley, Levi B. Wood
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-21 (2024)
Abstract Repetitive mild traumatic brain injuries (rmTBI) sustained within a window of vulnerability can result in long term cognitive deficits, depression, and eventual neurodegeneration associated with tau pathology, amyloid beta (Aβ) plaques, gli
Externí odkaz:
https://doaj.org/article/33fb43db821e412cb4a51344d8ea1517
Autor:
Prateek Kumar, Annie M. Goettemoeller, Claudia Espinosa-Garcia, Brendan R. Tobin, Ali Tfaily, Ruth S. Nelson, Aditya Natu, Eric B. Dammer, Juliet V. Santiago, Sneha Malepati, Lihong Cheng, Hailian Xiao, Duc D. Duong, Nicholas T. Seyfried, Levi B. Wood, Matthew J. M. Rowan, Srikant Rangaraju
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-26 (2024)
Abstract Dysfunction in fast-spiking parvalbumin interneurons (PV-INs) may represent an early pathophysiological perturbation in Alzheimer’s Disease (AD). Defining early proteomic alterations in PV-INs can provide key biological and translationally
Externí odkaz:
https://doaj.org/article/4a3d7575d66340e7b52ba0e5a848ab2b
Autor:
Kenneth A. Wilson, Sudipta Bar, Eric B. Dammer, Enrique M. Carrera, Brian A. Hodge, Tyler A. U. Hilsabeck, Joanna Bons, George W. Brownridge, Jennifer N. Beck, Jacob Rose, Melia Granath-Panelo, Christopher S. Nelson, Grace Qi, Akos A. Gerencser, Jianfeng Lan, Alexandra Afenjar, Geetanjali Chawla, Rachel B. Brem, Philippe M. Campeau, Hugo J. Bellen, Birgit Schilling, Nicholas T. Seyfried, Lisa M. Ellerby, Pankaj Kapahi
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Dietary restriction (DR) delays aging, but the mechanism remains unclear. We identified polymorphisms in mtd, the fly homolog of OXR1, which influenced lifespan and mtd expression in response to DR. Knockdown in adulthood inhibited DR-mediat
Externí odkaz:
https://doaj.org/article/3db7a1cee89643b094c27462834817ac
Autor:
Anantharaman Shantaraman, Eric B. Dammer, Obiadada Ugochukwu, Duc M. Duong, Luming Yin, E. Kathleen Carter, Marla Gearing, Alice Chen-Plotkin, Edward B. Lee, John Q. Trojanowski, David A. Bennett, James J. Lah, Allan I. Levey, Nicholas T. Seyfried, Lenora Higginbotham
Publikováno v:
Molecular Neurodegeneration, Vol 19, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/801efc043f6b4cd1b3e3be375e9c13aa
Autor:
Kamil Borkowski, Nicholas T. Seyfried, Matthias Arnold, James J. Lah, Allan I. Levey, Chadwick M. Hales, Eric B. Dammer, Colette Blach, Gregory Louie, Rima Kaddurah-Daouk, John W. Newman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Integration of the omics data, including metabolomics and proteomics, provides a unique opportunity to search for new associations within metabolic disorders, including Alzheimer’s disease. Using metabolomics, we have previously profiled o
Externí odkaz:
https://doaj.org/article/8bf68a11806b4e5a948a71379d7cd203
Autor:
Erica S. Modeste, Lingyan Ping, Caroline M. Watson, Duc M. Duong, Eric B. Dammer, Erik C. B. Johnson, Blaine R. Roberts, James J. Lah, Allan I. Levey, Nicholas T. Seyfried
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-19 (2023)
Abstract Background Despite being twice as likely to get Alzheimer’s disease (AD), African Americans have been grossly underrepresented in AD research. While emerging evidence indicates that African Americans with AD have lower cerebrospinal fluid
Externí odkaz:
https://doaj.org/article/7b366553a40942d589b546c51e93941a