Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Eric Assier"'
Autor:
Nadia Belmellat, Luca Semerano, Noria Segueni, Diane Damotte, Patrice Decker, Bernhard Ryffel, Valérie Quesniaux, Marie-Christophe Boissier, Eric Assier
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
Tumor necrosis factor-alpha (TNF-α) blockade is an effective treatment for rheumatoid arthritis (RA) and other inflammatory diseases, but in patients, it is associated with reduced resistance to the infectious agents Mycobacterium tuberculosis and L
Externí odkaz:
https://doaj.org/article/1ad22f7fb2d14c0ea175a6f9aaf9d1b0
Publikováno v:
Seminars in Immunopathology. 39:469-486
Animal models of arthritis are used to better understand pathophysiology of a disease or to seek potential therapeutic targets or strategies. Focusing on models currently used for studying rheumatoid arthritis, we show here in which extent models wer
Autor:
Valérie F. J. Quesniaux, Luca Semerano, Patrice Decker, Marie-Christophe Boissier, Eric Assier, Nadia Belmellat, Bernhard Ryffel
Publikováno v:
Novel technologies.
Background TNF-α-blocking therapy is a successful treatment strategy for rheumatoid arthritis (RA), but is associated with reduced resistance to tuberculosis. We have developed a vaccine against mouse TNF-α (TNF-KLH) which protects mice from collag
Publikováno v:
Frontiers in Pharmacology
Autor:
Emilie Duvallet, Luca Semerano, Jean-François Zagury, Marie-Christophe Boissier, Laure Delavallée, Rojo Ratsimandresy, Natacha Bessis, Eric Assier
Publikováno v:
Vaccine. 29:9329-9336
Introduction IL-23 is a pro-inflammatory cytokine essential for the differentiation of Th17 lymphocytes, a subtype of T lymphocyte implied in auto-immunity. IL-23 shares a subunit with IL-12, IL-12/23p40, and comprises a specific subunit, IL-23p19. W
Publikováno v:
Joint Bone Spine. 77:532-536
Interleukin-6 (IL-6) was identified based on extensive research conducted simultaneously on a variety of topics ranging from hepatocyte production of acute-phase proteins to plasmacytoma growth. IL-6 is a cytokine produced by a broad array of cell ty
Publikováno v:
Revue du Rhumatisme. 77:S16-S22
Resume L’interleukine-6 (IL-6) a ete caracterisee apres un long travail de recherche mene simultanement par des equipes travaillant sur des sujets aussi differents que la production des proteines de la phase aigue par les hepatocytes ou la croissan
Autor:
Anne Denys, Marie-Christophe Boissier, Géraldine Falgarone, Jérôme Biton, Eric Assier, Natacha Bessis
Publikováno v:
Joint Bone Spine. 76:10-14
Modulation of the T-cell response depends chiefly on regulatory T cells (Treg), which express CD4 and CD25. Some Treg cells are present naturally, whereas others are induced in response to antigens. The immunomodulating effects of Treg cells are medi
Autor:
Anne Denys, Marie-Christophe Boissier, Eric Assier, Natacha Bessis, Jérôme Biton, Géraldine Falgarone
Publikováno v:
Revue du Rhumatisme. 76:10-15
Resume La modulation de la reponse lymphocytaire T repose en grande partie sur une population de lymphocytes T appelee T regulateurs (Treg), dont le phenotype est CD4+CD25++. Il existe des lymphocytes Treg naturels et des lymphocytes T induits en rep
Autor:
Nuala Mooney, Anne Galy, Laurence Jeanson Leh, Dominique Charron, Catherine Gelin, Eric Assier, Alix Delaguillaumie, Viviana Marin-Esteban, Niclas Setterblad
Publikováno v:
European Journal of Immunology. 38:1096-1105
MHC class II-mediated antigen presentation by B lymphocytes or dendritic cells (DC) initiates CD4+ T lymphocyte activation. In B lymphocytes, MHC class II peptide presentation has been characterised by recruitment of MHC class II, F-actin and lipid r