Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eric Aragon"'
Autor:
Joan Pous, Blazej Baginski, Pau Martin-Malpartida, Lorena González, Margherita Scarpa, Eric Aragon, Lidia Ruiz, Rebeca A. Mees, Javier Iglesias-Fernández, Modesto Orozco, Angel R. Nebreda, Maria J. Macias
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract Many functional aspects of the protein kinase p38α have been illustrated by more than three hundred structures determined in the presence of reducing agents. These structures correspond to free forms and complexes with activators, substrate
Externí odkaz:
https://doaj.org/article/5db9dbcc41a443aea05c543a36e1e73e
Autor:
Lidia Ruiz, Zuzanna Kaczmarska, Tiago Gomes, Eric Aragon, Carles Torner, Regina Freier, Blazej Baginski, Pau Martin-Malpartida, Natàlia de Martin Garrido, José. A. Marquez, Tiago N. Cordeiro, Radoslaw Pluta, Maria J. Macias
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 632-646 (2021)
Smad transcription factors are the main downstream effectors of the Transforming growth factor β superfamily (TGFβ) signalling network. The DNA complexes determined here by X-ray crystallography for the Bone Morphogenetic Proteins (BMP) activated S
Externí odkaz:
https://doaj.org/article/10ae5e5507dd41e3bcbef079abb5af1f
Autor:
Radoslaw Pluta, Eric Aragon, Nicholas Prescott, Blazej Baginski, Lidia Ruiz, Julia Flood, Pau Martin-Malpartida, Joan Massague, Yael David, María Macías
Nucleosomes are barriers for the binding of most transcription factors, but pioneer factors (PFs) do bind and facilitate subsequent interactions of other proteins during transcription activation. FoxH1 is a maternal PF essential during embryonic deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21cc179dbaaec380ef1b0e24c8dc3ac6
https://doi.org/10.21203/rs.3.rs-1522438/v1
https://doi.org/10.21203/rs.3.rs-1522438/v1
Autor:
Y W Lau, Hui-Kim Yap, Yiong-Huak Chan, Eric Aragon, Kar Hui Ng, H L Loh, Puay Hoon Tan, Lourdes Paula R Resontoc
Publikováno v:
Lupus. 25(4)
We have previously reported the one-year outcomes of 16 children with severe proliferative lupus nephritis (LN) who were treated using a multi-targeted induction protocol based on intravenous (IV) pulse methylprednisolone (MP), mycophenolate mofetil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497389b1aa1c3f66b4fec1c34953b0d1
https://pubmed.ncbi.nlm.nih.gov/26537422
https://pubmed.ncbi.nlm.nih.gov/26537422
Publikováno v:
Lupus. 19(8)
The outcomes of children with severe proliferative lupus nephritis (LN) were examined using a new mycophenolate and cyclosporine-based (MMF—CSA) induction protocol. Sixteen children with LN (WHO class III and IV), 31.3% of whom required dialysis at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e0706860cc1e4feb47b0efb91bc6ca0
https://pubmed.ncbi.nlm.nih.gov/20581019
https://pubmed.ncbi.nlm.nih.gov/20581019
Autor:
W. D. Vindya N. Gunasekara, Lee-Kean Lim, Yiong-Huak Chan, Hui-Kim Yap, Wee-Song Yeo, Eric Aragon, Kar-Hui Ng, Pei-Pei Foong, Chien-Wyei Liew, Yew-Weng Lau
Publikováno v:
Pediatric nephrology (Berlin, Germany). 25(10)
Chronic peritoneal dialysis (PD) for children in Singapore was instituted in 1988 at the National University Hospital with adult nurses providing dialysis services during the first 10 years. In 1998, a specialist pediatric dialysis nursing team was r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c66b9e473b9c5712d805a5163810fb84
https://pubmed.ncbi.nlm.nih.gov/20559665
https://pubmed.ncbi.nlm.nih.gov/20559665
Autor:
Álvaro Rol, Toni Todorovski, Pau Martin-Malpartida, Anna Escolà, Elena Gonzalez-Rey, Eric Aragón, Xavier Verdaguer, Mariona Vallès-Miret, Josep Farrera-Sinfreu, Eduard Puig, Jimena Fernández-Carneado, Berta Ponsati, Mario Delgado, Antoni Riera, Maria J. Macias
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Inflammatory bowel disease is caused by chronic inflammation of the gastrointestinal tract and disturbed immune responses. Here the authors present examination of Cortistatin analogues that display enhanced half-life stability whilst maintaining immu
Externí odkaz:
https://doaj.org/article/538094955b874388ace1e053acd30f22
Autor:
Regina Freier, Eric Aragón, Błażej Bagiński, Radoslaw Pluta, Pau Martin-Malpartida, Lidia Ruiz, Miriam Condeminas, Cayetano Gonzalez, Maria J. Macias
Publikováno v:
IUCrJ, Vol 8, Iss 2, Pp 281-294 (2021)
Thioredoxins (Trxs) are ubiquitous enzymes that regulate the redox state in cells. In Drosophila, there are two germline-specific Trxs, Deadhead (Dhd) and thioredoxin T (TrxT), that belong to the lethal(3)malignant brain tumor signature genes and to
Externí odkaz:
https://doaj.org/article/af238065ce634e0696fc25d54648569c
Autor:
Tze-Liang Oi, Yew-Weng Lau, Kee Seng Chia, Chien-Wyei Liew, Hui-Kim Yap, Christopher Yap, Eric Aragon, Pei-Pei Foong, Alison Joanne Lee, Kevin Kho, Lee-Kean Lim
Publikováno v:
Pediatric nephrology (Berlin, Germany). 24(12)
Computerized kinetic modeling is a valuable automated peritoneal dialysis (APD) prescription tool for optimizing dialysis adequacy. However, non-compliance results in failure to achieve adequacy targets. The aim of this study was to determine if a no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df56febe7f892f18b5118ef6b38f73ec
https://pubmed.ncbi.nlm.nih.gov/19644710
https://pubmed.ncbi.nlm.nih.gov/19644710
Autor:
Tiago Gomes, Pau Martin-Malpartida, Lidia Ruiz, Eric Aragón, Tiago N. Cordeiro, Maria J. Macias
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 5210-5224 (2021)
SMAD transcription factors, the main effectors of the TGFβ (transforming growth factor β) network, have a mixed architecture of globular domains and flexible linkers. Such a complicated architecture precluded the description of their full-length (F
Externí odkaz:
https://doaj.org/article/6ffb0740739c4e5897f2e9b46bc8698c