Výsledky vyhledávání - "Eric A.F. van Tol"

Human Milk Short-Chain Fatty Acid Composition is Associated with Adiposity Outcomes in Infants

Autor: Philippa Prentice, Tim T. Lambers, Eric A.F. van Tol, Jacques Vervoort, Albert Koulman, Marieke H. Schoemaker, Carlo L. Acerini, David B. Dunger, Clive J. Petry, Ieuan A. Hughes, Ken K. Ong, Kasper Hettinga, Laurentya Olga

Publikováno v: The Journal of Nutrition, 149(5), 716-722
The Journal of Nutrition 149 (2019) 5

BACKGROUND: Presumed benefits of human milk (HM) in avoiding rapid infancy weight gain and later obesity could relate to its nutrient composition. However, data on breast milk composition and its relation with growth are sparse. OBJECTIVE: We investi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f42b22250973c0c4e9000dfcb7443
https://doi.org/10.1093/jn/nxy320

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Soluble Mediators From Lactobacillus rhamnosus Gorbach-Goldin Support Intestinal Barrier Function in Rats After Massive Small-Bowel Resection

Autor: Jiang Wu, Qingya Tang, Yan Zhong, Gabriele Gross, Eric A.F. van Tol, Kefeng Yang, Wenjie Wu, Wei Cai, Tim T. Lambers

Publikováno v: Journal of Parenteral and Enteral Nutrition. 42:1026-1034

Background Intestinal barrier plays an essential role in maintaining gastrointestinal health. This study aimed to explore the effects of a soluble mediator preparation derived from Lactobacillus rhamnosus Gorbach-Goldin (LGG) on intestinal barrier fu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::263dc86569fca1a97acfc0c0eb88a024
https://doi.org/10.1002/jpen.1044

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Long-chain polyunsaturated fatty acids and extensively hydrolyzed casein-induced browning in a Ucp-1 reporter mouse model of obesity

Autor: Liufeng Mao, Tim T. Lambers, Bingxiu Ma, Jiwen Lei, Eric A.F. van Tol, Tao Nie, Marieke H. Schoemaker, Yan Zhong, Donghai Wu, Yulai Zhou

Publikováno v: Food & Function. 9:2362-2373

Browning in adipose tissues, which can be affected by diet, may mitigate the detrimental effects of adiposity and improve longer-term metabolic health. Here, browning-inducing effects of long-chain polyunsaturated fatty acids, e.g., arachidonic acid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba6dfb0f433317ac47ad040c46b5c36
https://doi.org/10.1039/c7fo01835e

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Lactoferrin protects against intestinal inflammation and bacteria-induced barrier dysfunctionin vitro

Autor: Eric A.F. van Tol, Nina A. Hering, Gabriele Gross, Susanne M. Krug, Jörg D. Schulzke, Stephanie Wiegand, Julia Luettig, Rita Rosenthal

Publikováno v: Annals of the New York Academy of Sciences. 1405:177-188

The iron-binding glycoprotein lactoferrin (LF) is naturally present in human breast milk. Several studies suggest that LF contributes to infant health and development owing to a variety of protective effects, including antimicrobial and anti-inflamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::585711f1519bea1890035c6cb0522098
https://doi.org/10.1111/nyas.13405

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Nutritional Ingredients Modulate Adipokine Secretion and Inflammation in Human Primary Adipocytes

Autor: Eric A.F. van Tol, Tania Romacho, Jürgen Eckel, Philipp Glosse, Manuela Elsen, Isabel Richter, Marieke H. Schoemaker

Publikováno v: Nutrients
Volume 7
Issue 2
Pages 865-886
Nutrients, 7(2):865-886
Nutrients, Vol 7, Iss 2, Pp 865-886 (2015)

Nutritional factors such as casein hydrolysates and long chain polyunsaturated fatty acids have been proposed to exert beneficial metabolic effects. We aimed to investigate how a casein hydrolysate (eCH) and long chain polyunsaturated fatty acids cou

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d30dad1c3e49f798bdc417e3534e8ee9
https://doi.org/10.3390/nu7020865

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A casein hydrolysate based formulation attenuates obesity and associated non-alcoholic fatty liver disease and atherosclerosis in LDLr-/-.Leiden mice

Autor: Eric A.F. van Tol, Marieke H. Schoemaker, Robert Kleemann, Martine C. Morrison, Kanita Salic, Teake Kooistra, Peter Y. Wielinga, Joanne Verheij

Publikováno v: PLoS ONE, Vol 12, Iss 7, p e0180648 (2017)
PLoS ONE, 12(7). Public Library of Science
PLoS ONE

Background: Obesity frequently associates with the development of non-alcoholic fatty liver disease (NAFLD) and atherosclerosis. Chronic inflammation in white adipose tissue (WAT) seems to be an important driver of these manifestations. Objective: Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b459a57fa5553ad7c999a5aec53c0c
http://europepmc.org/articles/PMC5498059?pdf=render

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Arachidonic acid/docosahexaenoic acid-supplemented diet in early life reduces body weight gain, plasma lipids, and adiposity in later life in ApoE*3Leiden mice

Autor: Lars Verschuren, Zeina Jouni, Eric A.F. van Tol, Teake Kooistra, Peter Y. Wielinga, Marieke H. Schoemaker, Robert Kleemann, Lucien F. Harthoorn

Publikováno v: Molecular Nutrition & Food Research. 56:1081-1089

Scope: This study addresses whether early life arachidonic acid (ARA)/docosahexaenoic acid (DHA) supplementation or eicosapentaenoic acid (EPA)/DHA (Omacor) supplementation affects body weight gain, lipid metabolism, and adipose tissue quantity and q

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd73897228396021fcc0b446ed123797
https://doi.org/10.1002/mnfr.201100762

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The SCFA butyrate stimulates the epithelial production of retinoic acid via inhibition of epithelial HDAC

Autor: Wouter J. de Jonge, Tim T. Lambers, Eric A.F. van Tol, Caroline Verseijden, Vanesa Muncan, Ronald Schilderink, Gijs R. van den Brink, Jurgen Seppen

Publikováno v: American journal of physiology. Gastrointestinal and liver physiology, 310(11), G1138-G1146. American Physiological Society

In the intestinal mucosa, retinoic acid (RA) is a critical signaling molecule. RA is derived from dietary vitamin A (retinol) through conversion by aldehyde dehydrogenases (aldh). Reduced levels of short-chain fatty acids (SCFAs) are associated with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aea8627a1bbd9bae9b57628c37867c0
https://pubmed.ncbi.nlm.nih.gov/27151945

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Butyrate stimulates the epithelial potential to produce retinoic acid demonstrated in primary epithelial enteroid systems

Autor: Tim T. Lambers, Eric A.F. van Tol, Caroline Verseijden, Ronald Schilderink, Wouter J. de Jonge

Publikováno v: The FASEB Journal. 29

Reduced levels of the short chain fatty acid (SCFA) butyrate are associated with microbial dysbiosis and disease development. Butyrate serves as main energy source in colonocytes and is purported t...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3af6bcc82c5ef23b0e9a74d8feb1cf27
https://doi.org/10.1096/fasebj.29.1_supplement.847.1

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