Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Eric A. Wilson"'
Autor:
David Chmielewski, Eric A. Wilson, Grigore Pintilie, Peng Zhao, Muyuan Chen, Michael F. Schmid, Graham Simmons, Lance Wells, Jing Jin, Abhishek Singharoy, Wah Chiu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Coronavirus spike glycoproteins presented on the virion surface mediate receptor binding, and membrane fusion during virus entry and constitute the primary target for vaccine and drug development. How the structure dynamics of the full-lengt
Externí odkaz:
https://doaj.org/article/59f6e796a34541e8ac45dd396b94428c
Autor:
Min Chen, Eric A. Wilson, Zhenzhong Cui, Hui Sun, Yogendra B. Shrestha, Brandon Podyma, Christina H. Le, Benedetta Naglieri, Karel Pacak, Oksana Gavrilova, Lee S. Weinstein
Publikováno v:
Molecular Metabolism, Vol 25, Iss , Pp 142-153 (2019)
Objective: Gsα couples multiple receptors, including the melanocortin 4 receptor (MC4R), to intracellular cAMP generation. Germline inactivating Gsα mutations lead to obesity in humans and mice. Mice with brain-specific Gsα deficiency also develop
Externí odkaz:
https://doaj.org/article/89acb52d5bae4dd38d177087aca8704b
Autor:
Shamayeeta Ray, Samuel P Berry, Eric A Wilson, Casey H Zhang, Mrinal Shekhar, Abhishek Singharoy, Rachelle Gaudet
Publikováno v:
eLife, Vol 12 (2023)
Transporters of the Nramp (Natural resistance-associated macrophage protein) family import divalent transition metal ions into cells of most organisms. By supporting metal homeostasis, Nramps prevent diseases and disorders related to metal insufficie
Externí odkaz:
https://doaj.org/article/31a6a8e80ee44293aea58786ccac961d
Autor:
Benjamin A Y Cher, Eric A Wilson, Alexa M Pinsky, Ryan F Townshend, Ann V Wolski, Michael Broderick, Allison M Milen, Audrey Lau, Amrit Singh, Sandro K Cinti, Carl G Engelke, Anjan K Saha
Publikováno v:
Journal of Medical Internet Research, Vol 23, Iss 11, p e28105 (2021)
BackgroundDuring the initial months of the COVID-19 pandemic, rapidly rising disease prevalence in the United States created a demand for patient-facing information exchanges that addressed questions and concerns about the disease. One approach to ma
Externí odkaz:
https://doaj.org/article/5558bfd039a14e0a9241bf1c7b4a3671
Publikováno v:
Nature Climate Change
Residential GHG emissions in the United States are driven in part by a housing stock where on-site fossil combustion is common, home sizes are large by international standards, energy efficiency potential is large, and electricity generation in many
Publikováno v:
The Journal of Arthroplasty.
Publikováno v:
The Journal of Arthroplasty.
Autor:
Shamayeeta Ray, Samuel P. Berry, Eric A. Wilson, Casey H. Zhang, Mrinal Shekhar, Abhishek Singharoy, Rachelle Gaudet
Transporters of the Nramp (Natural resistance-associated macrophage protein) family import divalent transition metal ions into cells of most organisms. By supporting metal homeostasis, Nramps prevent disorders related to metal insufficiency or overlo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33217888a801279e2a18f2045f8fd2c4
https://doi.org/10.1101/2022.09.08.507188
https://doi.org/10.1101/2022.09.08.507188
Publikováno v:
Cancer Research. 83:5376-5376
The ability to accurately identify peptide ligands for a given major histocompatibility complex class I (MHC-I) molecule has immense value for targeted anticancer therapeutics. However, the highly polymorphic nature of the MHC-I protein makes univers