Zobrazeno 1 - 10
of 102
pro vyhledávání: '"Eric A. Parkinson"'
Autor:
Barbara Schwertner, George Dahdal, Wolfgang Jagla, Luis Grossmann, Konstantin Drexler, Michael P. Krahn, Katja Evert, Mark Berneburg, Sebastian Haferkamp, Christine Ziegler, Eric K. Parkinson, Grit Zahn, Maria E. Mycielska, Andreas Gaumann
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
We have recently shown that cancer cells of various origins take up extracellular citrate through the plasma membrane citrate carrier (pmCiC), a specific plasma membrane citrate transporter. Extracellular citrate is required to support cancer cell me
Externí odkaz:
https://doaj.org/article/0e8a6ba44376475d8a649d023b9f0b09
Publikováno v:
Molecular Oncology, Vol 16, Iss 8, Pp 1625-1649 (2022)
Alterations of the Hippo–YAP pathway are potential targets for oral squamous cell carcinoma (OSCC) therapy, but heterogeneity in this pathway could be responsible for therapeutic resistance. We analysed the Hippo–YAP signatures in a cohort of cha
Externí odkaz:
https://doaj.org/article/f6b3c64eea6f4670b6cbc92bfc7981c6
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/710e31d77845457ab88afa0fb069c0fc
Publikováno v:
Frontiers in Dental Medicine, Vol 3 (2022)
Cellular senescence is an irreversible cell cycle arrest occurring following multiple rounds of cell division (replicative senescence) or in response to cellular stresses such as ionizing radiation, signaling imbalances and oxidative damage (stress-i
Externí odkaz:
https://doaj.org/article/2b449faeabb34790b15c3b32e92a4921
Autor:
Yunying Huang, Hana Jedličková, Yang Cai, Ambreen Rehman, Luke Gammon, Usama Sharif Ahmad, Jutamas Uttagomol, Eric Kenneth Parkinson, Farida Fortune, Hong Wan
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Pemphigus Vulgaris (PV) is a life-threatening autoimmune disease manifested with blisters in the skin and mucosa and caused by autoantibodies against adhesion protein desmoglein-3 (Dsg3) expressed in epithelial membrane linings of these tissues. Desp
Externí odkaz:
https://doaj.org/article/d552e93411844ce6a68f4dd42c302970
Autor:
Emma Naomi James, Virag Sagi-Kiss, Mark Bennett, Maria Elzbieta Mycielska, Lee Peng Karen-Ng, Terry Roberts, Sheila Matta, Inderjeet Dokal, Jacob Guy Bundy, Eric Kenneth Parkinson
Publikováno v:
The Journals of Gerontology: Series A. 78:780-789
The underlying mechanisms of plasma metabolite signatures of human aging and age-related diseases are not clear but telomere attrition and dysfunction are central to both. Dyskeratosis congenita (DC) is associated with mutations in the telomerase enz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e9a68704640708b745a8ae48ec92a73
https://doi.org/10.1093/gerona/glad018
https://doi.org/10.1093/gerona/glad018
Autor:
Muy-Teck Teh, Hong Wan, Ahmad Waseem, Eric K. Parkinson, Daniela Elena-Costea, Emilios Gemenetzidis
Supplementary Methods, Table 1, Figures 1-4 from Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239cfe59d7aca6890734b5a2589b3b04
https://doi.org/10.1158/0008-5472.22384952.v1
https://doi.org/10.1158/0008-5472.22384952.v1
Publikováno v:
Cancer Letters. 518:102-114
This study reviews the molecular landscape of oral potentially malignant disorders (OPMD). We examine the impact of tumour heterogeneity, the spectrum of driver mutations (TP53, CDKN2A, TERT, NOTCH1, AJUBA, PIK3CA, CASP8) and gene transcription on tu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98044664d20b685652838b7959b19c5d
https://doi.org/10.1016/j.canlet.2021.05.025
https://doi.org/10.1016/j.canlet.2021.05.025
Autor:
Lee Peng Karen-Ng, Usama Sharif Ahmad, Luis Gomes, Keith David Hunter, Hong Wan, Eleni Hagi-Pavli, Eric Kenneth Parkinson
Publikováno v:
Cancers; Volume 14; Issue 11; Pages: 2636
Potentially pre-malignant lesions (PPOLs) are composed of keratinocytes that are either mortal (MPPOL) or immortal (IPPOL) in vitro. We report here that MPPOL, but not generally IPPOL keratinocytes upregulate various extracellular tumor promoting cyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ba3473082ab818901e361c871525e4
https://doi.org/10.1101/2022.03.10.483769
https://doi.org/10.1101/2022.03.10.483769
Telomerase deficiency in humans is associated with systemic age-related changes in energy metabolism
Autor:
Emma Naomi James, Virag Sagi-Kiss, Mark Bennett, Maria Mycielska, Karen-Ng Lee Peng, Terry Roberts, Sheila Matta, Inderjeet Dokal, Jacob Guy Bundy, Eric Kenneth Parkinson
SUMMARYUnderlying mechanisms of plasma metabolite signatures of human ageing and age-related diseases are not clear but telomere attrition and dysfunction are central to both. Dyskeratosis Congenita (DC) is associated with mutations in the telomerase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb985c37c1cebb51f33556c8770e6788
https://doi.org/10.1101/2022.02.28.481982
https://doi.org/10.1101/2022.02.28.481982