Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eric A. Mosser"'
Publikováno v:
The Journal of Neuroscience. 36:1823-1840
The hypothalamus plays an important role in regulating sleep, but few hypothalamic sleep-promoting signaling pathways have been identified. Here we demonstrate a role for the neuropeptide QRFP (also known as P518 and 26RFa) and its receptors in regul
Autor:
Tsuyoshi Hirota, May Hui, David A. Prober, Suna Li, Eric A. Mosser, Steve A. Kay, Chanpreet Singh, Amy Wang, Andrew Giovanni, Cindy N. Chiu, T. Katherine Tamai
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
The circadian clock ensures that behavioral and physiological processes occur at appropriate times during the 24-hour day/night cycle, and is regulated at both the cellular and organismal levels. To identify pathways acting on intact animals, we perf
Autor:
Eric A. Mosser, Brett J. Niles, Marc Vidal, Daniel A. Lee, Sridhara Chakravarthy, Jae Engle, Christin J. Montz, Cindy N. Chiu, Alexander F. Schier, Jason Rihel, Steven Zimmerman, David A. Prober, Viveca Sapin, Uyen Pham, Chanpreet Singh, Shijia Chen, Kourosh Salehi-Ashtiani
Neuromodulation of arousal states ensures that an animal appropriately responds to its environment and engages in behaviors necessary for survival. However, the molecular and circuit properties underlying neuromodulation of arousal states such as sle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92fbf8298a34de578eb55be4549d54d
https://europepmc.org/articles/PMC4851465/
https://europepmc.org/articles/PMC4851465/
Publikováno v:
Biochemistry. 37:13686-13695
Tandem binding sites for the hematopoietic transcription factor NF-E2 in the beta-globin locus control region activate high-level beta-globin gene expression in transgenic mice. NF-E2 is a heterodimer consisting of a hematopoietic subunit p45 and a u
Autor:
Eric A. Mosser, Elizabeth Kutter, Katherine Gailbreath, Holly K. Dressman, Burton Guttman, Julia Tracy, Patrick Paddison, James Neitzel, Stephen T. Abedon
Publikováno v:
Genetics. 148:1539-1550
Seldom has the study of a set of genes contributed more to our understanding of molecular genetics than has the characterization of the rapid-lysis genes of bacteriophage T4. For example, T4 rII mutants were used to define gene structure and mutagen
Cadherins play a key role in the dynamics of cell–cell contact formation and remodeling of junctions and tissues. Cadherin–cadherin interactions are gated by extracellular Ca 2+ , which serves to rigidify the cadherin extracellular domains and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95e782a9a7b1b5a8998abd842568e598
https://europepmc.org/articles/PMC3116393/
https://europepmc.org/articles/PMC3116393/
Publikováno v:
Neuron
Activity-induced changes in adhesion molecules may coordinate presynaptic and postsynaptic plasticity. Here, we demonstrate that beta-catenin, which mediates interactions between cadherins and the actin cytoskeleton, moves from dendritic shafts into
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0571cd012912440eb43ba35c7537ddbb
https://hdl.handle.net/21.11116/0000-0007-EF7C-2
https://hdl.handle.net/21.11116/0000-0007-EF7C-2
Autor:
Neal G. Copeland, Judith Kimble, Eric A. Mosser, Kirby D. Johnson, Kai Huang, Thomas L. Vandergon, Andrei Petcherski, Emery H. Bresnick, Nancy A. Jenkins
Publikováno v:
Gene. 252(1-2)
The highly conserved ubiquitin/proteasome pathway controls the degradation of many critical regulatory proteins. Proteins are posttranslationally conjugated to ubiquitin through a concerted set of reactions involving activating (E1), conjugating (E2)
Autor:
Tatiana N. Zaboikina, E. Camilla Forsberg, Emery H. Bresnick, Eric A. Mosser, Kirby D. Johnson
Publikováno v:
The Journal of biological chemistry. 274(38)
Four erythroid-specific DNase I-hypersensitive sites at the 5'-end of the beta-globin locus confer high-level transcription to the beta-globin genes. To identify coactivators that mediate long-range transactivation by this locus control region (LCR),
Publikováno v:
Neuron. (6):1193-1199
SummarySleep is an evolutionarily conserved behavioral state whose regulation is poorly understood. A classical model posits that sleep is regulated by homeostatic and circadian mechanisms. Several factors have been implicated in mediating the homeos