Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Eric A. Mercer"'
Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia
Autor:
Dan Lindholm, Rodrigo Martinez, Michael Besselmann, Thorsten Trapp, Laura Korhonen, Eric A. Mercer
Publikováno v:
Molecular and Cellular Neuroscience. 23:302-313
X-chromosome linked inhibitor of apoptosis protein (XIAP) is a member of the inhibitor of apoptosis protein (IAP) family and known to inhibit death of various cells under different experimental conditions. Although present in brain tissue, little is
Autor:
Eric A. Mercer, Ylva Skoglösa, Laura Korhonen, Dan Lindholm, Per-Anders Olsson, Jyrki P. Kukkonen
Publikováno v:
The EMBO Journal. 19:3597-3607
Inhibitor-of-apoptosis proteins (IAPs), including neuronal apoptosis inhibitory protein (NAIP), inhibit cell death. Other IAPs inhibit key caspase proteases which effect cell death, but the mechanism by which NAIP acts is unknown. Here we report that
Publikováno v:
The Journal of Neuroscience. 14:2455-2463
The promoter region of the human dopamine beta-hydroxylase (DBH) gene was analyzed in transgenic mice to identify DNA sequences responsible for the tissue- and cell-specific expression of the gene. Transgenic mice were generated that carried the Esch
Publikováno v:
Neuron. 7:703-716
Dopamine β-hydroxylase (DBH) catalyzes the final step in the biosynthesis of norepinephrine, the principal classic neurotransmitter of peripheral sympathetic neurons. We have shown that 5.8 kb of 5′ upstream region from a cloned human DBH gene pro
Publikováno v:
Neuron. 7:717-727
The 5′ flanking region from the human dopamine β-hydroxylase gene directs expression of bacterial β-galactosidase reporter genes to a subset of adult neurons and adrenal chromaffin cells of transgenic mice. In this paper, we examine the spatial a
Autor:
Iqtidar A. Khalil, Eric I. Mercer
Publikováno v:
Journal of Agricultural and Food Chemistry. 39:404-407
The effect of a systemic fungicide, fenpropimorph (Corbel/Mistal BASF), on the growth and sterol biosynthesis of wheat (Triticum aestivum L.) and maize (Zea mays L.) seedlings was studied to assess its phytotoxicity. Application of 250 μM fungicide
Publikováno v:
Plant Science. 66:21-28
Triadimefon, diclobutrazol (1R2R + 1S2S-isomer mixture) and R,R-diclobutrazol (1R2R-isomer) applied as soil drenchess retarded the growth of maize (cv. ‘Brutus’) seedlings. Although the treated seedlings appeared intensely green, the chlorophyll
Publikováno v:
Formal Methods in Computer Aided Design (FMCAD'07).
Autor:
Urmas Arumäe, Li Ying Yu, Laura Korhonen, Yuming Chen, Jyrki P. Kukkonen, Dan Lindholm, Eric A. Mercer
Publikováno v:
Biochimica et biophysica acta. 1600(1-2)
Neuronal apoptosis inhibitory protein (NAIP) has been linked to the inherited disease, spinal muscular atrophy (SMA), which occurs in children with degeneration of the motorneurons. In the nervous system, NAIP is expressed by specific classes of neur
Publikováno v:
The Journal of biological chemistry. 274(51)
The ERM protein family members ezrin, radixin, and moesin are cytoskeletal effector proteins linking actin to membrane-bound proteins at the cell surface. Here we report on the cloning of myosin regulatory light chain interacting protein (MIR), a pro