Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Eric A. Joseph"'
Autor:
Chao Wang, Sung-Wook Nam, John M. Cotte, Christopher V. Jahnes, Evan G. Colgan, Robert L. Bruce, Markus Brink, Michael F. Lofaro, Jyotica V. Patel, Lynne M. Gignac, Eric A. Joseph, Satyavolu Papa Rao, Gustavo Stolovitzky, Stanislav Polonsky, Qinghuang Lin
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
The wide use of microfluidics for biological analysis demands scalable preparation methods, yet in practice it is very challenging. Here, Wanget al. show a wafer-scale fabrication of nanofluidic chips with single-digit nanometre dimension, which is c
Externí odkaz:
https://doaj.org/article/8dfe6382a6f3435d9401956b405c4b22
Publikováno v:
International Journal of Consumer Studies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::acfbbf3c9c4ca476ecd178dd0cd93825
https://doi.org/10.1111/ijcs.12947
https://doi.org/10.1111/ijcs.12947
Autor:
Toshiyuki Sakai, Yuko Aoki, Neal Rosen, Poulikos I. Poulikakos, Yoshihiro Sowa, Mikio Arisawa, Nobuo Shimma, Toshihiro Aoki, Hitoshi Iikura, Yukako Tachibana-Kondo, Yasushi Tomii, Yutaka Matsuda, Hiroshi Sakamoto, Takaaki Miura, Kazuhiro Ohara, Eric W. Joseph, Naoki Harada, Nobuya Ishii
Tumors with mutant RAS are often dependent on extracellular signal–regulated kinase (ERK) signaling for growth; however, MEK inhibitors have only marginal antitumor activity in these tumors. MEK inhibitors relieve ERK-dependent feedback inhibition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d6d6624da24b766920d5ee7c74276a2
https://doi.org/10.1158/0008-5472.c.6504354.v1
https://doi.org/10.1158/0008-5472.c.6504354.v1
Autor:
Toshiyuki Sakai, Yuko Aoki, Neal Rosen, Poulikos I. Poulikakos, Yoshihiro Sowa, Mikio Arisawa, Nobuo Shimma, Toshihiro Aoki, Hitoshi Iikura, Yukako Tachibana-Kondo, Yasushi Tomii, Yutaka Matsuda, Hiroshi Sakamoto, Takaaki Miura, Kazuhiro Ohara, Eric W. Joseph, Naoki Harada, Nobuya Ishii
Supplementary Figure S1 - PDF file 70K, Induction of p27Kip1 protein and cell cycle arrest by CH5126766
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b272c3326137d6cf173146780cfce50
https://doi.org/10.1158/0008-5472.22395636.v1
https://doi.org/10.1158/0008-5472.22395636.v1
Autor:
Toshiyuki Sakai, Yuko Aoki, Neal Rosen, Poulikos I. Poulikakos, Yoshihiro Sowa, Mikio Arisawa, Nobuo Shimma, Toshihiro Aoki, Hitoshi Iikura, Yukako Tachibana-Kondo, Yasushi Tomii, Yutaka Matsuda, Hiroshi Sakamoto, Takaaki Miura, Kazuhiro Ohara, Eric W. Joseph, Naoki Harada, Nobuya Ishii
Supplementary Materials and Methods - PDF file 65K, Antibodies and kinase panel assays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01d3675432925f1de4e4eff25dee105c
https://doi.org/10.1158/0008-5472.22395624
https://doi.org/10.1158/0008-5472.22395624
Autor:
Toshiyuki Sakai, Yuko Aoki, Neal Rosen, Poulikos I. Poulikakos, Yoshihiro Sowa, Mikio Arisawa, Nobuo Shimma, Toshihiro Aoki, Hitoshi Iikura, Yukako Tachibana-Kondo, Yasushi Tomii, Yutaka Matsuda, Hiroshi Sakamoto, Takaaki Miura, Kazuhiro Ohara, Eric W. Joseph, Naoki Harada, Nobuya Ishii
Supplementary Table S4 - PDF file 56K, Binding constant between MEK1 and BRAF or CRAF, related to Figure 3. His6-MEK1 binding to immobilized GST-BRAF or GST-CRAF in the presence of 500 �M ATP, 500 �M ATP plus 3 �M CH5126766 or 500 �M ATP plus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cb4d2e4156d82909bbdadae41ecaab4
https://doi.org/10.1158/0008-5472.22395612
https://doi.org/10.1158/0008-5472.22395612
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-9 (2024)
Abstract As CRISPR effectors like Cas9 increasingly enter clinical trials for therapeutic gene editing, a future for personalized medicine will require efficient methods to protect individuals from the potential of off-target mutations that may also
Externí odkaz:
https://doaj.org/article/5cd19ad84b7d4e66a9d5f83c42255c0f
Autor:
Afsaneh Sadremomtaz, Robert F. Glass, Jorge Eduardo Guerrero, Dennis R. LaJeunesse, Eric A. Josephs, Reza Zadegan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract While the archival digital memory industry approaches its physical limits, the demand is significantly increasing, therefore alternatives emerge. Recent efforts have demonstrated DNA’s enormous potential as a digital storage medium with su
Externí odkaz:
https://doaj.org/article/3ad2e592e01546e2a9a008be9a19e0b3
Autor:
Ashish V. Jagtiani, Hiroyuki Miyazoe, Tz. B. Petrova, George Petrov, Eric A. Joseph, David R. Boris, Sandra C. Hernández, Evgeniya H. Lock, Scott G. Walton, Sebastian Engelmann
Publikováno v:
Microelectronic Engineering. 168:89-96
The Naval Research Laboratory (NRL) has developed a processing system based on an electron beam-generated plasma, where unlike conventional discharges produced by electric fields (DC, RF, microwave, etc.), ionization is driven by a high-energy (~ keV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c9088b3972a37ec9468c5025a23a47c
https://doi.org/10.1016/j.mee.2016.11.003
https://doi.org/10.1016/j.mee.2016.11.003
Autor:
Scott G. Walton, Hiroyuki Miyazoe, David R. Boris, Sebastian Engelmann, Samantha G. Rosenberg, Eric A. Joseph
Publikováno v:
Journal of Vacuum Science & Technology A. 39:033002
In the ideal case, plasma-enhanced atomic layer etching enables the ability to not only remove one monolayer of material but also leave adjacent layers undamaged. This dual mandate requires fine control over the flux of species to ensure efficacy, wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dbedcab433fbe89ca5e5d0083bbb00b
https://doi.org/10.1116/6.0000868
https://doi.org/10.1116/6.0000868