Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Eric A. Galburt"'
Autor:
Drake Jensen, Ana Ruiz Manzano, Maxwell Rector, Eric J. Tomko, M. Thomas Record, Eric A. Galburt
Publikováno v:
bioRxiv
The first step in gene expression is the transcription of DNA sequences into RNA. Regulation at the level of transcription leads to changes in steady-state concentrations of RNA transcripts, affecting the flux of downstream functions and ultimately c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd30cc58fb16fe5ea00fa27145e8d38
https://doi.org/10.1101/2023.03.13.532464
https://doi.org/10.1101/2023.03.13.532464
Autor:
Ankita Chadda, Drake Jensen, Eric J. Tomko, Ana Ruiz Manzano, Binh Nguyen, Timothy M. Lohman, Eric A. Galburt
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Significance Mycobacterium tuberculosis ( Mtb ) is an intracellular pathogen that causes tuberculosis and is exposed to oxidative insults from immune system macrophages. Mtb UvrD1 plays a role in DNA repair during infection and has been suggested to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8829f899785e925ee60f1e9377ec05b7
https://doi.org/10.1073/pnas.2114501119
https://doi.org/10.1073/pnas.2114501119
Autor:
Ankita Chadda, Eric A. Galburt
Publikováno v:
Biophysical Journal. 122:355a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebdbf8b00d0c68de2efe328497d0934e
https://doi.org/10.1016/j.bpj.2022.11.1965
https://doi.org/10.1016/j.bpj.2022.11.1965
Autor:
Jerome Prusa, Dennis X. Zhu, Aidan J. Flynn, Drake Jensen, Ana Ruiz Manzano, Eric A. Galburt, Christina L. Stallings
Publikováno v:
The Journal of biological chemistry. 298(4)
RNA polymerase (RNAP) binding protein A (RbpA) is essential for mycobacterial viability and regulates transcription initiation by increasing the stability of the RNAP-promoter open complex (RP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af91898cf70a2df5789e1ef4c382cf7
https://pubmed.ncbi.nlm.nih.gov/35189142
https://pubmed.ncbi.nlm.nih.gov/35189142
Autor:
Ankita Chadda, Drake Jensen, Eric J. Tomko, Ana Ruiz Manzano, Binh Nguyen, Timothy M. Lohman, Eric A. Galburt
Publikováno v:
Biophysical Journal. 121:446a-447a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07ec1e6e3cf160758c8f30569d2921ea
https://doi.org/10.1016/j.bpj.2021.11.542
https://doi.org/10.1016/j.bpj.2021.11.542
Publikováno v:
Proceedings of the National Academy of Sciences. 116:13573-13581
The ability to regulate gene expression through transcription initiation underlies the adaptability and survival of all bacteria. Recent work has revealed that the transcription machinery in many bacteria diverges from the paradigm that has been esta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a7a819d251b7ff270479f26a44f95c8
https://doi.org/10.1073/pnas.1900176116
https://doi.org/10.1073/pnas.1900176116
Publikováno v:
Nucleic Acids Research
The pathogen Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, enacts unique transcriptional regulatory mechanisms when subjected to host-derived stresses. Initiation of transcription by the Mycobacterial RNA polymerase (RNAP) ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49d56065bd0e3cf432c3fd9538a75923
https://doi.org/10.1093/nar/gkz449
https://doi.org/10.1093/nar/gkz449
Autor:
Eric J. Tomko, Eric A. Galburt
Publikováno v:
Methods. :35-44
The initiation of transcription underlies the ability of cells to modulate genome expression as a function of both internal and external signals and the core process of initiation has features that are shared across all domains of life. Specifically,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51dc560df72fc16309f0f09ffc283c2f
https://doi.org/10.1016/j.ymeth.2019.03.010
https://doi.org/10.1016/j.ymeth.2019.03.010
Autor:
De Bona P, Alex S. Holehouse, Roberto Galletto, Andrea Soranno, J. Jeremías Incicco, Eric J. Tomko, Eric A. Galburt
Publikováno v:
Journal of Molecular Biology. 434:167685
Telomeres are nucleoprotein complexes that protect the ends of chromosomes and are essential for chromosome stability in Eukaryotes. In cells, individual telomeres form distinct globules of finite size that appear to be smaller than expected for bare
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bcb10f7290e18f76cb6900d76bac541
https://doi.org/10.1016/j.jmb.2022.167685
https://doi.org/10.1016/j.jmb.2022.167685
Autor:
Drake Jensen, Eric A. Galburt
Publikováno v:
J Bacteriol
The fitness of an individual bacterial cell is highly dependent upon the temporal tuning of gene expression levels when subjected to different environmental cues. Kinetic regulation of transcription initiation is a key step in modulating the levels o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb590b586d0068915c7fc33a12bcd4b2
https://europepmc.org/articles/PMC8088511/
https://europepmc.org/articles/PMC8088511/