Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eric A. Forssen"'
Autor:
Eric A. Forssen, Michael Willis
Publikováno v:
Advanced Drug Delivery Reviews. 29:249-271
Liposomes have gained increased attention as systemic drug delivery vehicles following recent regulatory approvals of several vesicle-formulated drugs. These products have demonstrated improved therapeutic indices over their corresponding conventiona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27c9c5973b5444cf09469505357d451f
https://doi.org/10.1016/s0169-409x(97)00083-5
https://doi.org/10.1016/s0169-409x(97)00083-5
Autor:
Eric A. Forssen
Publikováno v:
Advanced Drug Delivery Reviews. 24:133-150
This article reviews the formulation development and characterization of the tumor-targeting daunorubicin liposome preparation, DaunoXome®. The identification of liposome formulations capable of delivering their contents to solid tumors in vivo was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5533b8a83f136dde7d44f8eeb2fa83da
https://doi.org/10.1016/s0169-409x(96)00453-x
https://doi.org/10.1016/s0169-409x(96)00453-x
Autor:
Douglas D. Richman, Suezanne Parker, Channa Basava, Linda Selk, Rathna Basava, Michael Gardner, Karl Y. Hostetler, Eric A. Forssen
Publikováno v:
Biochemical Pharmacology. 48:1399-1404
The aspartyl protease of the human immunodeficiency virus (HIV) is an important target for chemotherapeutic intervention because of its key role in cleaving the HIV gag-pol polyprotein during viral assembly and budding. Short peptides and peptidomime
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be60baab94f39fc9a004eb4147590e27
https://doi.org/10.1016/0006-2952(94)90563-0
https://doi.org/10.1016/0006-2952(94)90563-0
Autor:
Michael E. Ross, Eric A. Forssen
Publikováno v:
Journal of Liposome Research. 4:481-512
Daunorubicin has been entrapped into small unilamellar vesicles (50-80 nm dia) composed of a 2:1 mole ratio of highly purified DSPC:cholesterol. In earlier studies, liposomes of this size and composition had been demonstrated to deliver their entrapp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a65695ee9b52f8472fdc688e726cf4e
https://doi.org/10.3109/08982109409037058
https://doi.org/10.3109/08982109409037058
Publikováno v:
Long Circulating Liposomes: Old Drugs, New Therapeutics ISBN: 9783662221174
Kaposi’s sarcoma, the most common tumor occurring in human immunodeficiency virus (HIV)-infected individuals and persons with the acquired immunodeficiency syndrome (AIDS), has become a more aggressive, increasingly difficult-totreat tumor partly b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a1c7fcf9f0340f465022e02a7d1dbea
https://doi.org/10.1007/978-3-662-22115-0_10
https://doi.org/10.1007/978-3-662-22115-0_10
Publikováno v:
Medical Applications of Liposomes
This chapter explores unilamellar liposomes for anticancer, DaunoXome and antifungal, AmBisome, therapy. Visceral leishmaniasis (VL) is endemic in many areas of the world, more prevalent in areas nearer to the equator and, including the Mediterranean
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8dc46630ab25b94578942cdc26907fc6
https://doi.org/10.1016/b978-044482917-7/50037-5
https://doi.org/10.1016/b978-044482917-7/50037-5
Publikováno v:
Long Circulating Liposomes: Old Drugs, New Therapeutics ISBN: 9783662221174
This chapter reviews the formulation research, development, and characterization of a tumor-targeting daunorubicin liposome preparation with a long circulating half-life (DaunoXome®). The identification of liposome formulations capable of delivering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::467ebf980da34b6c776041802a805b1a
https://doi.org/10.1007/978-3-662-22115-0_6
https://doi.org/10.1007/978-3-662-22115-0_6
Autor:
Eric A. Forssen, Michael E. Ross, Franco M. Muggia, Alexandra M. Levine, Howard A. Liebman, Suzanne Cabriales, Joan A. Esplin, Parkash S. Gill, Byron M. Espina, Anil Tulpule
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 13(4)
PURPOSE Since liposomal encapsulation of anticancer drugs may enhance antitumor activity while reducing toxicity in vitro, we evaluated liposomally encapsulated daunorubucin (DaunoXome; Vestar, Inc, San Dimas, CA) for safety, pharmacokinetics, and po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8fe22e147101ba66346702920e3157b
https://pubmed.ncbi.nlm.nih.gov/7707129
https://pubmed.ncbi.nlm.nih.gov/7707129
Autor:
Eric A. Forssen, Zoltán A. Tökés
Publikováno v:
Proceedings of the National Academy of Sciences. 78:1873-1877
Anionic liposomes containing doxorubicin were evaluated in mice for therapeutic potential in reducing the risks of chronic cardiotoxicity characteristic of long-term high-dose anthracycline therapy. Doxorubicin first was complexed to phosphatidylchol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::606b93c9bf74c4c9cda8729419864a6e
https://doi.org/10.1073/pnas.78.3.1873
https://doi.org/10.1073/pnas.78.3.1873
Autor:
Zoltán A. Tőkés, Eric A. Forssen
Publikováno v:
Biochemical and biophysical research communications. 91(4)
Liposome entrapped adriamycin retains its full cytotoxic potential when tested under in vitro conditions against murine leukemia L-1210 cells. In vivo drug distribution studies indicate that, relative to the free drug, a lower proportion of adriamyci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87287603b4569e9ec5c13f45b6e4e05b
https://pubmed.ncbi.nlm.nih.gov/526304
https://pubmed.ncbi.nlm.nih.gov/526304