Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Eric A. Drier"'
Autor:
Aaron A. Hoskins, Matt Kirk, Eric A. Drier, William O'Brien, Joshua Donald Larson, James F. Mackay, Larry J. Friedman
Publikováno v:
Nature Protocols. 9:2317-2328
Colocalization Single Molecule Spectroscopy (CoSMoS) has proven to be a useful method for studying the composition, kinetics, and mechanisms of complex cellular machines. Key to the technique is the ability to simultaneously monitor multiple proteins
Autor:
Scott A. Barbee, Eric A. Drier, Marvin Wickens, Jerry C. P. Yin, Mani Ramaswami, Jae Eun Kwak
Publikováno v:
Proceedings of the National Academy of Sciences. 105:14644-14649
The formation of long-term memory is believed to require translational control of localized mRNAs. In mammals, dendritic mRNAs are maintained in a repressed state and are activated upon repetitive stimulation. Several regulatory proteins required for
New Synaptic Bouton Formation Is Disrupted by Misregulation of Microtubule Stability in aPKC Mutants
Autor:
Catalina Ruiz-Canada, Stephanie Moeckel-Cole, Eric A. Drier, Vivian Budnik, Jerry C. P. Yin, James A. Ashley
Publikováno v:
Neuron. 42:567-580
The Baz/Par-3-Par-6-aPKC complex is an evolutionarily conserved cassette critical for the development of polarity in epithelial cells, neuroblasts, and oocytes. aPKC is also implicated in long-term synaptic plasticity in mammals and the persistence o
Autor:
Nancy Blace, Priscilla Wu, Eric A. Drier, Todd Charlton Sacktor, Maureen Cowan, Marcela K. Tello, Jerry C. P. Yin
Publikováno v:
Nature Neuroscience. 5:316-324
Synaptic stimulation activates signal transduction pathways, producing persistently active protein kinases. PKMzeta is a truncated, persistently active isoform of atypical protein kinase C-zeta (aPKCzeta), which lacks the N-terminal pseudosubstrate r
Autor:
Eric A. Drier, Ruth Steward
Publikováno v:
Seminars in Cancer Biology. 8:83-92
Embryonic dorsoventral polarity in Drosophila melanogaster is determined by a maternally-encoded signal transduction pathway whose effector molecule is the Rel transcription factor, Dorsal. The activity of this signal transduction pathway gives rise
Autor:
John E. McCartney, Lynne Lederman, Gay-May Wu, James S. Huston, Roberta S. Batorsky, Hermann Oppermann, Eric A. Drier, Nancy A. Cabral-Denison
Publikováno v:
Journal of Protein Chemistry. 10:669-683
The functional antigen binding region of antidinitrophenol mouse IgA myeloma MOPC 315 has been produced as a single-chain Fv (sFv) protein in E. coli. Recombinant 315 proteins included sFv alone, a bifunctional fusion protein with amino-terminal frag
Publikováno v:
Current biology : CB. 10(1)
Rel-family transcription factors function in a variety of biological processes, including development and immunity [1]. During early Drosophila development, the Toll-Cactus-Dorsal pathway regulates the establishment of the embryonic dorsoventral axis
Publikováno v:
Genesdevelopment. 13(5)
In Drosophila, dorsal-ventral polarity is determined by a maternally encoded signal transduction pathway that culminates in the graded nuclear localization of the Rel protein, Dorsal. Dorsal is retained in the cytoplasm by the IkappaB protein, Cactus
Publikováno v:
Molecular and cellular biology. 16(3)
The formation of a gradient of nuclear Dorsal protein in the early Drosophila embryo is the last step in a maternally encoded dorsal-ventral signal transduction pathway. This gradient is formed in response to a ventral signal, which leads to the diss
Publikováno v:
Neurobiology of Aging. 25:S434