Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Eric A. Butz"'
Autor:
Laura Crespo, Raquel Ríos León, Garbiñe Roy Ariño, Natalia Vicente López, Ana De Andrés, María Garriga, Carlota García-Hoz, Eric A. Butz, Francisco Leon, Almudena Santón
Publikováno v:
Digestive diseases (Basel, Switzerland). 38(6)
Background: Refractory celiac disease type II (RCD-II) is a very rare yet severe complication of celiac disease (CD) with a 50% rate of progression to Enteropathy-associated T-cell lymphoma (EATL). Timely diagnosis and treatment of RCD-II is of the e
Autor:
Karin Schreiber, Andrea Schietinger, David C. Binder, Bana Jabri, Donald A. Rowley, Thomas Krausz, Boris Engels, Hans Schreiber, Ainhoa Arina, Rebecca B. Liu, Eric A. Butz, Elizabeth Hyjek
Publikováno v:
Cancer Research. 72:1964-1974
Natural killer (NK) cells inhibit early stages of tumor formation, recurrence, and metastasis. Here, we show that NK cells can also eradicate large solid tumors. Eradication depended on the massive infiltration of proliferating NK cells due to interl
Autor:
Sabina Buntich, Robert Ortiz, Babette M. Boren, Michelle Horner, Tsui C. Cheah, Suzanne T. Wolford, Wayne Tsuji, Eric A. Butz, Larry C. Wienkers, Jim J. Xiao, Herve Lebrec, Kathleen Köck, Wei. J. Pan, Hong Li, Samantha P. Prokop, Arunan Kaliyaperumal
Publikováno v:
Pharmacology Research & Perspectives
Hu714MuXHu is a recombinant chimeric murine-human monoclonal antibody directed against interleukin-15 (IL-15), a proinflammatory cytokine associated with memory CD8+ and natural killer (NK) T-cell activation and implicated in the pathogenesis of infl
Autor:
Alina C. Boesteanu, Constantinos Petrovas, Dong Xia, Eric A. Butz, Douglas V. Dolfi, Peter D. Katsikis
Publikováno v:
The Journal of Immunology. 180:2912-2921
The role of costimulation has previously been confined to the very early stages of the CD8+ T cell response. In this study, we demonstrate the requirement for CD27 costimulation during the later phase, but not programming of the primary CD8+ T cell r
Autor:
Hilary J. McKenna, Charles R. Maliszewski, Eric A. Butz, Jeffrey S. Smith, Mark Teepe, Elizabeth Daro
Publikováno v:
Cytokine. 17:119-130
Flt3 ligand (FL) and granulocyte-macrophage colony-stimulating factor (GM-CSF) are important growth factors for dendritic cells (DC). Substantial numbers of DC can be generated in vivo following the administration of either factor. We sought to exten
Autor:
Thibaut De Smedt, Eric A. Butz, Peter Robert Baum, William C. Fanslow, Charles R. Maliszewski, Jeffrey S. Smith
Publikováno v:
The Journal of Immunology. 168:661-670
Dendritic cells (DCs) are bone marrow-derived APCs that display unique properties aimed at stimulating naive T cells. Several members of the TNF/TNFR families have been implicated in T cell functions. In this study, we examined the role that Ox40 cos
Cytokine Requirements for Acute and Basal Homeostatic Proliferation of Naive and Memory CD8+ T Cells
Autor:
Christophe Benoist, Mary K. Kennedy, Ananda W. Goldrath, Michael J. Bevan, Diane Mathis, Moira Glaccum, Pallavur V. Sivakumar, Eric A. Butz
Publikováno v:
The Journal of Experimental Medicine
Both naive and memory T cells undergo antigen-independent proliferation after transfer into a T cell–depleted environment (acute homeostatic proliferation), whereas only memory T cells slowly divide in a full T cell compartment (basal proliferation
Autor:
Jeffrey S. Smith, Muriel Moser, Bernard Pajak, Thibaut De Smedt, Roberto Maldonado-López, Charles R. Maliszewski, Eric A. Butz
Publikováno v:
Journal of Leukocyte Biology. 69:951-958
Dendritic cells (DCs) are essential for the priming of immune responses. This antigen-presenting function of DCs develops in sequence in a process called maturation, during which they become potent sensitizers of naïve T cells but reduce their abili
Autor:
Mandy L. Shawver, Donald Drake, Annette Hadley, Eric A. Butz, Aron E. Lukacher, Charles R. Maliszewski
Publikováno v:
Journal of Virology. 75:544-547
Dendritic cells are pivotal antigen-presenting cells for generating adaptive T-cell responses. Here, we show that dendritic cells belonging to either the myeloid-related or lymphoid-related subset are permissive for infection by mouse polyomavirus an
Autor:
John D. Altman, Janice M. Moser, Aron E. Lukacher, Donald Drake, Charles R. Maliszewski, Eric A. Butz, Annette Hadley
Publikováno v:
Journal of Virology. 74:4093-4101
CD8+T cells are critical for the clearance of acute polyomavirus infection and the prevention of polyomavirus-induced tumors, but the antigen-presenting cell(s) involved in generating polyomavirus-specific CD8+T cells have not been defined. We invest