Zobrazeno 1 - 10
of 187
pro vyhledávání: '"Eric A Weaver"'
Autor:
The N. Nguyen, Danh C. Lai, Sarah Sillman, Erika Petro-Turnquist, Eric A. Weaver, Hiep L. X. Vu
Publikováno v:
mSphere, Vol 9, Iss 8 (2024)
ABSTRACT In 2009, a novel swine-origin H1N1 virus emerged, causing a pandemic. The virus, known as H1N1pdm09, quickly displaced the circulating H1 lineage and became the dominant seasonal influenza A virus subtype infecting humans. Human-to-swine spi
Externí odkaz:
https://doaj.org/article/dc26f0c53d6a45e5a688ca4d983cc249
Autor:
Richard J Webby, Eric A Weaver
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140702 (2015)
With the exception of the live attenuated influenza vaccine there have been no substantial changes in influenza vaccine strategies since the 1940's. Here we report an alternative vaccine approach that uses Adenovirus-vectored centralized hemagglutini
Externí odkaz:
https://doaj.org/article/cb60c9905eb248abbd66e53b4a0f2f81
Autor:
Eric A Weaver, Pramod N Nehete, Bharti P Nehete, Guojun Yang, Stephanie J Buchl, Patrick W Hanley, Donna Palmer, David C Montefiori, Guido Ferrari, Philip Ng, K Jagannadha Sastry, Michael A Barry
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67574 (2013)
Most HIV-1 infections are thought to occur at mucosal surfaces during sexual contact. It has been hypothesized that vaccines delivered at mucosal surfaces may mediate better protection against HIV-1 than vaccines that are delivered systemically. To t
Externí odkaz:
https://doaj.org/article/5ffa11f663e248b9a83ae41302d80f5d
Autor:
Eric A Weaver, Michael A Barry
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73313 (2013)
Seasonal and pandemic influenza remains a constant threat. While standard influenza vaccines have great utility, the need for improved vaccine technologies have been brought to light by the 2009 swine flu pandemic, highly pathogenic avian influenza i
Externí odkaz:
https://doaj.org/article/84efd630423c4fc7b4c0a1df276b6f92
Autor:
Matthew J. Pekarek, Eric A. Weaver
Publikováno v:
Pathogens, Vol 13, Iss 9, p 755 (2024)
As respiratory pathogens, influenza B viruses (IBVs) cause a significant socioeconomic burden each year. Vaccine and antiviral development for influenza viruses has historically viewed IBVs as a secondary concern to influenza A viruses (IAVs) due to
Externí odkaz:
https://doaj.org/article/00970cff88134e37b870302f80101844
Publikováno v:
Vaccines, Vol 12, Iss 8, p 943 (2024)
Swine influenza A virus (IAV-S) is a highly prevalent and transmissible pathogen infecting worldwide swine populations. Our previous work has shown that the computationally derived vaccine platform, Epigraph, can induce broadly cross-reactive and dur
Externí odkaz:
https://doaj.org/article/7cbe7f9bff4d4dfc8cb86aa348005ec2
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e18314 (2011)
Influenza poses a persistent worldwide threat to the human population. As evidenced by the 2009 H1N1 pandemic, current vaccine technologies are unable to respond rapidly to this constantly diverging pathogen. We tested the utility of adenovirus (Ad)
Externí odkaz:
https://doaj.org/article/5f4c5547b0034f4bb7b52c107e1383bd
Autor:
Sean E Hofherr, Kristen E Adams, Christopher Y Chen, Shannon May, Eric A Weaver, Michael A Barry
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17076 (2011)
The distribution of viruses and gene therapy vectors is difficult to assess in a living organism. For instance, trafficking in murine models can usually only be assessed after sacrificing the animal for tissue sectioning or extraction. These assays a
Externí odkaz:
https://doaj.org/article/0da95cd4a0fd4a75844982b7fac02ee7
Autor:
Eric A Weaver
Publikováno v:
PLoS ONE, Vol 5, Iss 8, p e12004 (2010)
BACKGROUND: Feline immunodeficiency virus (FIV) is a lentivirus associated with AIDS-like illnesses in cats and has been used as a model for the study of human immunodeficiency virus (HIV). A feature of HIV and FIV infection is the continually increa
Externí odkaz:
https://doaj.org/article/fd55dac131ba49218177615257c06f93
Autor:
Eric A Weaver, Pramod N Nehete, Stephanie S Buchl, Julien S Senac, Donna Palmer, Philip Ng, K Jagannadha Sastry, Michael A Barry
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e5059 (2009)
All studies using human serotype 5 Adenovirus (Ad) vectors must address two major obstacles: safety and the presence of pre-existing neutralizing antibodies. Helper-Dependent (HD) Ads have been proposed as alternative vectors for gene therapy and vac
Externí odkaz:
https://doaj.org/article/d7e3765c66b54c6b903b5f2f8e26af77